Results 171 to 180 of about 8,441,406 (356)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Studies on the cell wall of group A streptococcus, with special reference to the T antigen

, 1960
Makoto NAKAZAWA, Yuya Nakamura, Nobuyuki Sakai   +2 more
openalex   +2 more sources

Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera [PDF]

, 1979
Eiichi Nakayama, Hiroshi Shiku, Elisabeth Stockert, Herbert F. Oettgen, Lloyd J. Old   +4 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells

Communications Biology
Current differentiation protocols for human induced pluripotent stem cells (hiPSCs) produce heterogeneous cardiomyocytes (CMs). Although chamber-specific CM selection using cell surface antigens enhances biomedical applications, a cell surface marker ...
Misato Nakanishi-Koakutsu, Kenji Miki, Yuki Naka, Masako Sasaki, Takayuki Wakimizu, Stephanie C. Napier, Chikako Okubo, Megumi Narita, Misato Nishikawa, Reo Hata, Kazuhisa Chonabayashi, Akitsu Hotta, Kenichi Imahashi, Tomoyuki Nishimoto, Yoshinori Yoshida   +14 more
doaj   +1 more source

INDEPENDENT EXPRESSION OF HUMAN T CELL DIFFERENTIATION ANTIGENS AND E ROSETTE RECEPTOR ON PHYTOHEMAGGLUTININ-STIMULATED T LYMPHOCYTES

, 1978
P. A. Dougherty, Edwin W. Ades, Charles M. Balch   +2 more
openalex   +1 more source

Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression. [PDF]

, 1976
Mathew A. Vadas, J. F. A. P. Miller, Ian F. C. McKenzie, Stanley E. Chism, F W Shen, Edward A. Boyse, Jennifer R. Gamble, Alison Whitelaw   +7 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

T cell development in the chicken [PDF]

, 1994
Bernot, Bucy, Bucy, C.H. CHEN, Chan, Char, Chen, Chen, Chen, Chen, Chen, Cihak, Cihak, Cihak, Coltey, Coltey, Cooper, Davidson, Dunon, George, Göbel, Haas, Kasahara, Lahti, M.D. COOPER, McCormack, Quere, Schiffer, Sowder, T. KUBOTA, T.W.F. GÖBEL, Tjoelker, Veillette, Wyss-Coray   +33 more
core   +1 more source

T Cell Helper Defect in Patients with Chronic Lymphocytic Leukemia [PDF]

, 1979
Nicholas Chiorazzi, Shu Man Fu, Ghodrat Montazeri, Henry G. Kunkel, R. Kanti, Tracy A. Gee   +5 more
openalex   +1 more source