Results 171 to 180 of about 25,344,545 (360)

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

VIRUS-SPECIFIC NUCLEIC ACIDS IN SV40-EXPOSED HAMSTER EMBRYO CELL LINES: CORRELATION WITH S AND T ANTIGENS [PDF]

, 1969
Myron J. Levin, Michael N. Oxman, George Th. Diamandopoulos, Arthur S. Levine, Patrick H. Henry, John F. Enders   +5 more
openalex   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Illuminating T cell-dendritic cell interactions in vivo by FlAsHing antigens

eLife
Delineating the complex network of interactions between antigen-specific T cells and antigen presenting cells (APCs) is crucial for effective precision therapies against cancer, chronic infections, and autoimmunity.
Munir Akkaya, Jafar Al Souz, Daniel Williams, Rahul Kamdar, Olena Kamenyeva, Juraj Kabat, Ethan Shevach, Billur Akkaya   +7 more
doaj   +1 more source

Cells in Multidimensional Recurrent Neural Networks [PDF]

Journal of Machine Learning Research 17 (2016) 1-37, 2014
The transcription of handwritten text on images is one task in machine learning and one solution to solve it is using multi-dimensional recurrent neural networks (MDRNN) with connectionist temporal classification (CTC). The RNNs can contain special units, the long short-term memory (LSTM) cells.
arxiv  

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19

Cell, 2020
T. Sekine, André Perez-Potti, Olga Rivera-Ballesteros, K. Strålin, J. Gorin, Annika Olsson, S. Llewellyn-Lacey, Habiba Kamal, G. Bogdanovic, S. Muschiol, David Wullimann, Tobias Kammann, Johanna E. M. Emgård, Tiphaine Parrot, E. Folkesson, O. Rooyackers, L. Eriksson, A. Sönnerborg, T. Allander, J. Albert, M. Nielsen, J. Klingström, Sara Gredmark-Russ, N. Björkström, J. Sandberg, D. Price, H. Ljunggren, S. Aleman, M. Buggert   +28 more
semanticscholar   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

Nature, 2020
N. Le Bert, A. Tan, Kamini Kunasegaran, C. Tham, Morteza Hafezi, A. Chia, M. Chng, Meiyin Lin, N. Tan, M. Linster, W. Chia, M. Chen, Lin‐Fa Wang, E. Ooi, S. Kalimuddin, P. Tambyah, J. Low, Yee-Joo Tan, A. Bertoletti   +18 more
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

Nature, 2020
U. Şahin, A. Muik, E. Derhovanessian, I. Vogler, L. Kranz, M. Vormehr, A. Baum, Kristen E. Pascal, Jasmin Quandt, D. Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, R. Hilker, D. Becker, A. Eller, J. Grützner, Carsten Boesler, Corinna Rosenbaum, Marie-Cristine Kühnle, U. Luxemburger, Alexandra Kemmer-Brück, D. Langer, M. Bexon, S. Bolte, K. Karikó, T. Palanché, Boris Fischer, A. Schultz, P. Shi, Camila R. Fontes-Garfias, John L. Perez, K. Swanson, Jakob Loschko, Ingrid L Scully, Mark Cutler, W. Kalina, C. Kyratsous, David Cooper, P. Dormitzer, K. Jansen, Ö. Türeci   +41 more
semanticscholar   +1 more source