Results 181 to 190 of about 25,344,545 (360)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Dynamics of T Cell Receptor Distributions Following Acute Thymic Atrophy and Resumption [PDF]

open access: yesarXiv, 2019
Naive human T cells are produced in the thymus, which atrophies abruptly and severely in response to physical or psychological stress. To understand how an instance of stress affects the size and "diversity" of the peripheral naive T cell pool, we derive a mean-field autonomous ODE model of T cell replenishment that allows us to track the clone ...
arxiv  

A Human Leukemia Cell with Both B and T Cell Surface Receptors [PDF]

open access: green, 1974
Ethan M. Shevach   +4 more
openalex   +1 more source

CD8+ T cell differentiation and dysfunction in cancer

open access: yesNature reviews. Immunology, 2021
M. Philip, A. Schietinger
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Participation of Cyclophosphamide-Sensitive T Cells in Graft-vs-Host Reactions [PDF]

open access: bronze, 1976
Anthony L. Schwartz   +2 more
openalex   +1 more source

Axicabtagene Ciloleucel CAR T‐Cell Therapy in Refractory Large B‐Cell Lymphoma

open access: yesNew England Journal of Medicine, 2017
S. Neelapu   +39 more
semanticscholar   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Indoleamine-2,3-dioxygenase (IDO) Mediates the Suppression of T Cells by IFN-γ Primed Mesenchymal Stromal Cells in the Treatment of Psoriasis-Like Inflammation

open access: yesFrontiers in Bioscience-Landmark
Background: Psoriasis is a chronic and incurable skin inflammation driven by an abnormal immune response. Our study aims to investigate the potential of interferon-γ (IFN-γ) primed mesenchymal stem cells (IMSCs) in targeting T cells to
Weidong Zhu   +5 more
doaj   +1 more source

Cell-to-cell fusion

open access: yesCurrent Opinion in Cell Biology, 1989
Carl P. Blobel, Judith M. White
openaire   +3 more sources

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