Results 191 to 200 of about 8,441,406 (356)

T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histocompatibility complex-linked immune response genes. [PDF]

, 1979
A M Solinger, Michiel E. Ultee, E. Margoliash, R H Schwartz   +3 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Indolent peripheral T-cell lymphoma resembling Kimura's disease: a new variant of T-cell Lymphoma? [PDF]

Leuk Res Rep
Sun H, Feng J, Zhang Y, Zhang J, Lu S, Liu Y.   +5 more
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness. [PDF]

, 1978
Rolf M. Zinkernagel, Alana Althage, S Cooper, G. Kreeb, Paul Klein, Bartholomew M. Sefton, Lisa Flaherty, J. H. Stimpfling, Donald C. Shreffler, J Klein   +9 more
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Early CD4+ T cell proliferation and chronic T cell engagement impact myeloma outcomes following T cell engager therapy. [PDF]

J Clin Invest
Duffy AM, Goenka A, Azeem MI, Taz A, Potdar SV, Scott SA, Marin E, Kaufman JL, Hofmeister CC, Joseph NS, Gupta VA, Lonial S, Nooka AK, Dhodapkar MV, Dhodapkar KM.   +14 more
europepmc   +1 more source

Cutaneous T-cell lymphoma: neoplasm of T cells with helper activity [PDF]

, 1979
Berger Cl, D Warburton, Jahangir Raafat, P LoGerfo, Edelson Rl   +4 more
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Regulatory T cell therapy for xenotransplantation, what perspectives? [PDF]

Front Immunol
Porret R, Lana E, Mancarella A, Guillaume P, Pascual M, Meier RPH, Bromberg JS, Mohiuddin MM, Buhler LH, Tang Q, Muller YD.   +10 more
europepmc   +1 more source