Results 211 to 220 of about 28,819,884 (406)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Human Immunodeficiency Virus Integrates Directly into Naive Resting CD4⁺T Cells but Enters Naive Cells Less Efficiently than Memory Cells [PDF]

, 2009
Jihong Dai, Luis M. Agosto, Clifford Baytop, Jianqing Yu, Matthew Pace, Megan K. Liszewski, Una O’Doherty   +6 more
openalex   +1 more source

Single-cell immune profiling reveals functional diversity of T cells in tuberculous pleural effusion [PDF]

, 2022
Yi Cai, Yejun Wang, Chenyan Shi, Youchao Dai, Fuxiang Li, Yuzhong Xu, Peize Zhang, Fanhui Kong, Guofang Deng, Zhihua Wen, Qi Zhou, Boxi Kang, Amit Singhal, Qianting Yang, Carl G. Feng, Xinchun Chen   +15 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

T cell development in the chicken [PDF]

, 1994
Bernot, Bucy, Bucy, C.H. CHEN, Chan, Char, Chen, Chen, Chen, Chen, Chen, Cihak, Cihak, Cihak, Coltey, Coltey, Cooper, Davidson, Dunon, George, Göbel, Haas, Kasahara, Lahti, M.D. COOPER, McCormack, Quere, Schiffer, Sowder, T. KUBOTA, T.W.F. GÖBEL, Tjoelker, Veillette, Wyss-Coray   +33 more
core   +1 more source

Characteristics and anatomic location of PD-1 ⁺ TCF1 ⁺ stem-like CD8 T cells in chronic viral infection and cancer [PDF]

, 2023
Se Jin Im, Rebecca C. Obeng, Tahseen H. Nasti, Daniel T. McManus, Alice O. Kamphorst, Sivaram Gunisetty, Nataliya Prokhnevska, Jennifer W. Carlisle, Ke Yu, Gabriel Sica, Lucas Esteves Cardozo, André N. A. Gonçalves, Haydn Kissick, Helder I. Nakaya, Suresh S. Ramalingam, Rafi Ahmed   +15 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Low CD8+ T Cell Infiltration and High PD-L1 Expression Are Associated with Level of CD44+/CD133+ Cancer Stem Cells and Predict an Unfavorable Prognosis in Pancreatic Cancer [PDF]

, 2019
Ya-Chin Hou, Ying‐Jui Chao, Min-Hua Hsieh, Hui-Ling Tung, Hao‐Chen Wang, Yan‐Shen Shan   +5 more
openalex   +1 more source

Chimeric antigen receptor T-cell therapy — assessment and management of toxicities

Nature Reviews Clinical Oncology, 2018
S. Neelapu, S. Tummala, P. Kebriaei, W. Wierda, C. Gutierrez, F. Locke, K. Komanduri, Yi Lin, N. Jain, N. Daver, J. Westin, A. Gulbis, M. Loghin, J. Groot, S. Adkins, Suzanne E. Davis, K. Rezvani, P. Hwu, E. Shpall   +18 more
semanticscholar   +1 more source

Cell cycle, cell division, cell death

Molecular Biology of the Cell, 2019
Maddox, Amy Shaub, Skotheim, Jan M.
openaire   +2 more sources