Results 241 to 250 of about 28,819,884 (406)

Drug-loaded bispecific T cell nanoengager overcomes T cell exhaustion for potent cancer immunotherapy. [PDF]

Proc Natl Acad Sci U S A
Wang J, Huang X, Shi Q, Swingle KL, Hamilton AG, Gong N, Mitchell MJ.   +6 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Peripheral T cell lymphoma following CD19-targeted chimeric antigen receptor T cell therapy. [PDF]

Int J Hematol
Tatetsu H, Kato K, Wada A, Hirano T, Ueno S, Miyasato Y, Yamada A, Shichijo T, Higuchi Y, Ueda Y, Nosaka K, Mikami Y, Karube K, Matsuoka M, Yasunaga JI.   +14 more
europepmc   +1 more source

Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis

, 2021
Alyxzandria M. Gaydosik, Tracy Tabib, Robyn T. Domsic, Dinesh Khanna, Robert Lafyatis, Patrizia Fuschiotti   +5 more
openalex   +2 more sources

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

Proceedings of the National Academy of Sciences of the United States of America, 1980
B. Poiesz, F. Ruscetti, A. Gazdar, P. Bunn, J. Minna, R. Gallo   +5 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Indolent peripheral T-cell lymphoma resembling Kimura's disease: a new variant of T-cell Lymphoma? [PDF]

Leuk Res Rep
Sun H, Feng J, Zhang Y, Zhang J, Lu S, Liu Y.   +5 more
europepmc   +1 more source

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function

, 2019
Stalin Chellappa, Kushi Kushekhar, Ludvig A. Munthe, Geir E. Tjønnfjord, Einar Martin Aandahl, Klaus Okkenhaug, Kjetil Taskén   +6 more
openalex   +1 more source

Breast Tumor Microenvironment in Black Women: A Distinct Signature of CD8+ T-Cell Exhaustion

, 2020
Song Yao, Ting‐Yuan David Cheng, Ahmed Elkhanany, Li Yan, Angela R. Omilian, Scott I. Abrams, Sharon S. Evans, Chi-Chen Hong, Qianya Qi, Warren Davis, Song Liu, Elisa V. Bandera, Kunle Odunsi, Kazuaki Takabe, Thaer Khoury, Christine B. Ambrosone   +15 more
openalex   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source