Results 241 to 250 of about 8,676,743 (305)

Unlocking T cell exhaustion: Insights and implications for CAR-T cell therapy

Dian Xiong, Haijun Yu, Zhi‐Jun Sun
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

T cell-microbiome associations captured through T cell receptor convergence analysis

Vandoren R, Ha M, Van Deuren V, De Roeck N, Pu T, Brand EC, Kuznetsova M, Besbassi H, Bartholomeus E, Affaticati F, De Boeck I, Gehrmann T, Lebeer S, Oldenburg B, van Wijk F, Delputte P, Verbandt S, Tejpar S, Laukens K, Ogunjimi B, Meysman P.   +20 more
europepmc   +1 more source

Editorial: Enhancing CAR T-cell therapy with imaging. [PDF]

Front Immunol
Lopci E, de Jong D, Dercle L.
europepmc   +1 more source

Human cytomegalovirus UL23 exploits PD-L1 inhibitory signaling pathway to evade T cell-mediated cytotoxicity

琴二 栗原, Zhaosong Fan, Wenqiang Huang, Xiaoping Huo, Xiaoping Yang, Yanhong Ran, Jun Chen, Hongjian Li   +7 more
openalex   +1 more source

Contribution of regulatory T�cells to immune tolerance and association of microRNA‑210 and Foxp3 in preeclampsia

, 2018
Jiying Chen, Lijian Zhao, Dengchuan Wang, Yanbin Xu, Haijie Gao, Wenqing Tan, Chenhong Wang   +6 more
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Regulatory T cell approaches for graft-versus-host disease prevention. [PDF]

Curr Opin Immunol
Bader CS, Meyer EH, Negrin RS.
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Acquisition of an immunosuppressive microenvironment after anti-CD19 CAR T-cell therapy is associated with T-cell dysfunction and resistance. [PDF]

J Immunother Cancer
Ponzo M, Drufuca L, Buracchi C, Sindoni MM, Nucera S, Bugarin C, Bason R, Rossetti G, Bonnal R, Meli C, Rambaldi B, Lussana F, Ferrari S, Moretti A, Dastoli G, Risca G, Pellegrino C, Manz MG, Galimberti S, Rambaldi A, Gaipa G, Biondi A, Pagani M, Magnani CF.   +23 more
europepmc   +1 more source