Results 41 to 50 of about 29,027,932 (385)

Combination therapy with PD-1 blockade and radiofrequency ablation for recurrent hepatocellular carcinoma: a propensity score matching analysis

International Journal of Hyperthermia, 2021
Background This study aimed to evaluate whether combined therapy with PD-1 blockade (anti-PD-1) and radiofrequency ablation (RFA) is superior to RFA monotherapy for recurrent hepatocellular carcinoma (HCC).
Xiaofei Wang, Guo Liu, Shu Chen, Huaqiang Bi, Feng Xia, Kai Feng, Kuansheng Ma, Bing Ni   +7 more
doaj   +1 more source

EMMPRIN AND HUMAN β-DEFENSIN-3 – BIOMARKER MOLECULES IN PREMALIGNANT ORAL LESIONS: CORRELATIVE IMMUNOHISTOCHEMICAL STUDY

Romanian Journal of Oral Rehabilitation, 2021
Aim of the study The current pandemic context, with a significant negative impact on the oral mucosa pathology, requires intensified research on the risk of malignant transformation of the most common premalignant oral lesions, precursors of oral ...
Doinița Temelie-Olinici, Ana-Emanuela Botez, Oana-Mihaela Hrițcu-Condurache, Carmen Solcan, Vasile Bogdan Grecu, Laura Stoica, Pavel Onofrei, Carmen Elena Cotrutz   +7 more
doaj  

T cell responses in patients with COVID-19

Nature reviews. Immunology, 2020
The role of T cells in the resolution or exacerbation of COVID-19, as well as their potential to provide long-term protection from reinfection with SARS-CoV-2, remains debated.
Zeyu Chen, E. John Wherry
semanticscholar   +1 more source

Cell–cell and cell–matrix interactions

Molecular Biology of the Cell, 2012
Cell–cell and cell–extracellular matrix (ECM) interactions are fundamental to the complexity of multicellularity achieved in the metazoa. These interactions share many conceptual similarities, the most prominent being a dependence on transmembrane adhesion receptors, binding of adhesion receptors to specific extracellular ligand partners, and the ...
Josephine C. Adams, Kris A. DeMali
openaire   +2 more sources

Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse

Nature Communications, 2019
The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear.
Andres Ernesto Zucchetti, Laurence Bataille, Jean-Marie Carpier, Stéphanie Dogniaux, Mabel San Roman-Jouve, Mathieu Maurin, Michael W. Stuck, Rosa M. Rios, Cosima T. Baldari, Gregory J. Pazour, Claire Hivroz   +10 more
doaj   +1 more source

MHCII restriction demonstrates B cells have very limited capacity to activate tumour-specific CD4+ T cells in vivo

OncoImmunology
There has been growing interest in the role of B cells in antitumour immunity and potential use in adoptive cellular therapies. To date, the success of such therapies is limited.
Thomas V. Guy, Alexandra M. Terry, Helen M. McGuire, Elena Shklovskaya, Barbara Fazekas de St Groth   +4 more
doaj   +1 more source

Cell calcium, cell injury and cell death. [PDF]

Environmental Health Perspectives, 1984
The role of calcium in cell injury has been the subject of much recent investigation. The movement and redistribution of this cation from extra to intracellular compartments and the calcium shifts between intracellular compartments may well play a determinate role in the cell's reaction to injury.
Kauno U. Laiho, Nicholas DeClaris, Toshihide Sato, Irene K. Berezesky, Benjamin F. Trump, Patricia C. Phelps   +5 more
openaire   +3 more sources

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer [PDF]

, 2012
A summit on cellular therapy for cancer discussed and presented advances related to the use of adoptive cellular therapy for melanoma and other cancers. The summit revealed that this field is advancing rapidly.
A Lundqvist, A Somers, C Berger, CA Tran, Carolina Berger, Cornelis JM Melief, Daniel J Powell, David F Stroncek, DG Song, DJ Powell Jr, DL Porter, Francesco M Marincola, G Mostoslavsky, GG Kenter, Gustavo Mostoslavsky, J Jin, J Staerk, James R Heath, Jeffrey S Miller, JN Kochenderfer, JN Kochenderfer, John O'Shea, JS Miller, K Takahashi, L Gattinoni, L Gattinoni, L Gattinoni, L Gattinoni, LA Johnson, Luca Gattinoni, M Kalos, M Kalos, M Kalos, Mahendra Rao, Mark E Dudley, Martin A Cheever, ME Dudley, ME Dudley, Michael Kalos, Nicholas P Restifo, P Muranski, Peter Flynn, PF Robbins, RA Morgan, Richard W Childs, SA Rosenberg, Steven A Rosenberg, TS Park, X Wang   +48 more
core   +4 more sources

Differentiation of effector CD4 T cell populations (*).

Annual Review of Immunology, 2010
CD4 T cells play critical roles in mediating adaptive immunity to a variety of pathogens. They are also involved in autoimmunity, asthma, and allergic responses as well as in tumor immunity.
Jinfang Zhu, H. Yamane, W. Paul
semanticscholar   +1 more source

Cell–cell and cell–matrix interactions

Molecular Biology of the Cell, 2014
mbc.E13-11-0671 Molecular Biology of the Cell Volume 25 Page 731 MBoC is pleased to publish this summary of the Minisymposium “Cell−Cell/Cell−Matrix Interactions and Intracellular Signaling” held at the American Society for Cell Biology 2013 Annual Meeting, New Orleans, LA, December 15, 2013.
openaire   +3 more sources