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Human natural killer cell committed thymocytes and their relation to the T cell lineage. [PDF]
Recent studies have demonstrated that mature natural killer (NK) cells can be grown from human triple negative (TN; CD3-, CD4-, CD8-) thymocytes, suggesting that a common NK/T cell precursor exists within the thymus that can give rise to both NK cells ...
Lanier, LL+3 more
core +1 more source
ATOPIC DERMATITIS: FROM MOLECULAR SPECIFICITY OF ORAL MANIFESTATIONS TO CLINICAL IMPLICATIONS
Atopic dermatitis (AD) is considered a systemic disease that also manifests itself in the oral cavity. The presence of oral pathologies in patients with atopic dermatitis can result in the worsening of the atopic disease, and on the other hand, the ...
Petronela Bărgăoanu+4 more
doaj
Background This study aimed to evaluate whether combined therapy with PD-1 blockade (anti-PD-1) and radiofrequency ablation (RFA) is superior to RFA monotherapy for recurrent hepatocellular carcinoma (HCC).
Xiaofei Wang+7 more
doaj +1 more source
Cells within cells (within cells) [PDF]
![][1] Within 6 hours of detachment from their substrate, one cell becomes entirely enclosed by another. BRUGGE/ELSEVIER One tumor cell can burrow its way entirely inside another.
openaire +2 more sources
A cell atlas of human thymic development defines T cell repertoire formation
Thymus development, cell by cell The human thymus is the organ responsible for the maturation of many types of T cells, which are immune cells that protect us from infection.
Jong-Eun Park+41 more
semanticscholar +1 more source
Aim of the study The current pandemic context, with a significant negative impact on the oral mucosa pathology, requires intensified research on the risk of malignant transformation of the most common premalignant oral lesions, precursors of oral ...
Doinița Temelie-Olinici+7 more
doaj
Peptide Super-Agonist Enhances T-Cell Responses to Melanoma
Recent immunotherapeutic approaches using adoptive cell therapy, or checkpoint blockade, have demonstrated the powerful anti-cancer potential of CD8 cytotoxic T-lymphocytes (CTL).
Sarah A. E. Galloway+18 more
doaj +1 more source
Cell–cell and cell–matrix interactions
Cell–cell and cell–extracellular matrix (ECM) interactions are fundamental to the complexity of multicellularity achieved in the metazoa. These interactions share many conceptual similarities, the most prominent being a dependence on transmembrane adhesion receptors, binding of adhesion receptors to specific extracellular ligand partners, and the ...
Josephine C. Adams, Kris A. DeMali
openaire +2 more sources
Controversies concerning thymus-derived regulatory T cells: fundamental issues and a new perspective [PDF]
Thymus-derived regulatory T cells (Tregs) are considered to be a distinct T-cell lineage that is genetically programmed and specialised for immunosuppression.
Ono, M, Tanaka, RJ
core +1 more source
Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear.
Andres Ernesto Zucchetti+10 more
doaj +1 more source