Results 21 to 30 of about 4,664,465 (319)

T-cell memory: the importance of chemokine-mediated cell attraction [PDF]

, 2006
A recent study demonstrates the involvement of certain chemokines in immune response initiation and CD8+ T-cell memory formation.
Moser, Bernhard, Bernhard Moser
core   +1 more source

T–cell anergy and peripheral T–cell tolerance [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001
The discovery that T–cell recognition of antigen can have distinct outcomes has advanced understanding of peripheral T–cell tolerance, and opened up new possibilities in immunotherapy. Anergy is one such outcome, and results from partial T–cell activation.
R, Lechler, J G, Chai, F, Marelli-Berg, G, Lombardi   +3 more
openaire   +2 more sources

Immunological aspects of adult T-cell leukemia/lymphoma (ATLL), a possible neoplasm of regulatory T-cells [PDF]

, 2008
Adult T-cell leukemia/lymphoma (ATLL) is a distinct disease caused by the first discovered human oncogenic retrovirus, human T-cell leukemia virus type-1 (HTLV-1).
Yamada, Yasuaki, Kamihira, Shimeru, Yasuaki Yamada, Shimeru Kamihira   +3 more
core   +1 more source

Chronic Inflammation Links Cancer and Parkinson’s disease

Frontiers in Aging Neuroscience, 2016
An increasing number of genetic studies suggest that the pathogenesis of Parkinson’s disease (PD) and cancer share common genes, pathways, and mechanisms.
Zhiming eLi, Zhiming eLi, Zaozao eZheng, Zaozao eZheng, Jun eRuan, Jun eRuan, Zhi eLi, Zhi eLi, Chi-Meng eTzeng, Chi-Meng eTzeng, Chi-Meng eTzeng   +10 more
doaj   +1 more source

Downregulation of HMGB1 in thymoma cells affects T cell differentiation

Central European Journal of Immunology, 2023
Introduction: Thymoma is the most common anterior mediastinal tumor and is closely associated with myasthenia gravis (MG). Our previous study showed that the expression of Th17 cells increased and the expression of Treg decreased in MG-associated thymoma
Jian Li, Zeyang Zhang, Yuan Chen, Yuanguo Wang, Yuxin Liu, Peng Zhang   +5 more
doaj   +1 more source

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling [PDF]

, 2009
CD95 is a multifunctional receptor that induces cell death or proliferation depending on the signal, cell type, and cellular context. Here, we describe a thus far unknown function of CD95 as a silencer of T cell activation.
Lindquist, Jonathan, Strauss, Gudrun, Lindquist, Jonathan A., Arhel, Nathalie, Nathalie Arhel, Tobias L. Haas, Edward Felder, Fulda, Simone, Haas, Tobias L., Henning Walczak, Felder, Edward, Kirchhoff, Frank, Gudrun Strauss, Sabine Karl, Simone Fulda, Walczak, Henning, Karl, Sabine, Frank Kirchhoff, Klaus-Michael Debatin, Debatin, Klaus-Michael, Jonathan A. Lindquist, Haas, Tobias   +21 more
core   +1 more source

Metabolic regulation of regulatory T cell development and function [PDF]

, 2014
It is now well established that the effector T cell (Teff) response is regulated by a series of metabolic switches. Quiescent T cells predominantly require ATP-generating processes, whereas proliferating Teff require high metabolic flux through growth ...
Marelli-Berg, F, Madhav eKishore, Kishore, M, Federica eMarelli-Berg, Federica Marelli-Berg, Coe, DJ, David John Coe, Madhav Kishore   +7 more
core   +1 more source

T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development

Cell Reports, 2020
Summary: T cell factor 1 (Tcf1) promotes the central memory CD8+ T (TCM) cell differentiation and stemness in lymphoid tissues after systemic infections.
Jingxia Wu, Alaa Madi, Alessa Mieg, Agnes Hotz-Wagenblatt, Nina Weisshaar, Sicong Ma, Kerstin Mohr, Tilo Schlimbach, Marvin Hering, Helena Borgers, Guoliang Cui   +10 more
doaj   +1 more source

Ex-vivo CS1-OKT3 dual specific bivalent antibody-armed effector T cells mediate cellular immunity against multiple myeloma

Scientific Reports, 2023
Bispecific T cell engaging antibodies (bsAbs) have emerged as novel and powerful therapeutic agents for redirecting T cells towards antigen-specific tumor killing.
Dennis Awuah, Lin Li, Lindsay Williams, Ryan Urak, Maciej Kujawski, Stephen J. Forman, John E. Shively, Xiuli Wang   +7 more
doaj   +1 more source

Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome [PDF]

, 2021
The chronic neuro-inflammatory character of multiple sclerosis (MS) suggests that the natural process to resolve inflammation is impaired. This protective process is orchestrated by specialized pro-resolving lipid mediators (SPMs), but to date, the role ...
Silvia Martina Tietz, Alessandro Leuti, Valerio Chiurchiu, Serhan, Charles N, Tietz, Silvia Martina, Haghayegh Jahromi, Neda, Norris, Paul C, Schouten, Marijn, de Vries, Helga E., Neda Haghayegh Jahromi, Helga de Vries, Enzmann, Gaby, Charles N Serhan, Jahromi, Neda Haghayegh, Chiurchiù, Valerio, Gaby Enzmann, Kooij, Gijs, van der Pol, Susanne M. A., Engelhardt, Britta, van der Pol, Susanne M A, Britta Engelhardt, Norris, Paul C., Serhan, Charles N., Claudio Derata Troletti, Kamermans, Alwin, Leuti, Alessandro, Paul C Norris, de Vries, Helga E, Alwin Kamermans, Derada Troletti, Claudio, Gijs Kooij, Susanne M.A. van der Pol, Marijn Schouten,   +32 more
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