Results 241 to 250 of about 56,239 (298)

Medical software for precision diagnostics of infection with immunoprofiling and artificial intelligence. [PDF]

J Transl Med
Miho E, Marquez S, Stervbo U, Mertz KD, Kruta J, Schkommodau E, Pieter M.   +6 more
europepmc   +1 more source

Evolution of the tuberculin skin test reveals generalisable Mtb-reactive T cell metaclones. [PDF]

Nat Commun
Turner CT, Tiffeau-Mayer A, Rosenheim J, Chandran A, Saxena R, Zhang P, Jiang J, Berkeley M, Pang F, Uddin I, Nageswaran G, Byrne S, Karthikeyan A, Smidt W, Ogongo P, Byng-Maddick R, Capocci S, Lipman M, Kunst H, Lozewicz S, Ramsuran V, Pollara G, Knight JC, Leslie A, Chain BM, Noursadeghi M.   +25 more
europepmc   +1 more source

Delineation and monitoring of the T cell repertoire of adoptive cell transfer product during the treatment of advanced melanoma. [PDF]

Genome Med
Kerr C, Soleimani S, Mulder DT, Nabbi A, Gray D, Pedersen S, Sotov V, Sudhaman S, Nguyen L, Hirano N, Ohashi PS, Butler MO, Pugh TJ.   +12 more
europepmc   +1 more source

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T-Cell Repertoire Characterization

2022
T-cell repertoire characterization is a methodology that enables the identification of T-cell receptor (TCR) gene sequences in a T-cell population. TCR genes are composed of modular gene segments V (D) J that undergo somatic recombination, resulting in unique and unpredictable sequences that can be utilized to identify each T-cell clone.
Anna, Pasetto, Marcus, Buggert
openaire   +3 more sources

T Cell Receptor Repertoire Sequencing

2020
The status of T cell receptors (TCRs) repertoire is associated with the occurrence and progress of various diseases and can be used in monitoring the immune responses, predicting the prognosis of disease and other medical fields. High-throughput sequencing promotes the studying in TCR repertoire.
Huixin, Lin, Yonggang, Peng, Xiangbin, Chen, Yuebin, Liang, Geng, Tian, Jialiang, Yang   +5 more
openaire   +2 more sources

Quantitative annotations of T-Cell repertoire specificity

Briefings in Bioinformatics, 2023
Abstract The specificity of a T-cell receptor (TCR) repertoire determines personalized immune capacity. Existing methods have modeled the qualitative aspects of TCR specificity, while the quantitative aspects remained unaddressed. We developed a package, TCRanno, to quantify the specificity of TCR repertoires. We created deep-learning-
Jiaqi Luo, Xueying Wang, Yiping Zou, Lingxi Chen, Wei Liu, Wei Zhang, Shuai Cheng Li   +6 more
openaire   +2 more sources

Antigen-Driven T-Cell Repertoire Selection

Critical Reviews in Immunology, 2005
The immune system has evolved to combat infectious organisms through the coordination of both innate and acquired immune responses. Innate immune responses generally pass their roles in eradicating pathogens to acquired immune responses conducted by T and B cells. T and B cells generate diverse antigen-specific receptors through gene recombination, and
Yoichi, Maekawa, Koji, Yasutomo
openaire   +2 more sources