Results 161 to 170 of about 67,870 (201)

Correction: A new role for circulating T follicular helper cells in humoral response to anti-PD-1 therapy. [PDF]

J Immunother Cancer
europepmc   +1 more source

Regulation of the Function of T Follicular Helper Cells and B Cells in Type 1 Diabetes Mellitus by the OX40/OX40L Axis.

J Clin Endocrinol Metab
Du X, Zhu Y, Lu W, Fu N, Wang Q, Shi B.
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Differentiation of human T follicular helper cells in vitro requires co-operation between STAT3 and SMAD signaling cytokines that is restrained by IL-2

Foster WS, Labeur-Iurman L, Williams GS, Robinson MJ, Carlesso G, Lloyd CM, Harker JA.   +6 more
europepmc   +1 more source

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Revealing T follicular helper cells with BCL6

Nature Reviews Immunology, 2021
Shane Crotty discusses three independent studies published in 2009 that characterized T follicular helper cells as a distinct subset of CD4+ T cells on the basis of selective expression of BCL6.
Shane Crotty
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T follicular helper cells and T follicular regulatory cells in rheumatic diseases

Nature Reviews Rheumatology, 2019
As a hallmark of autoimmune rheumatic diseases, autoantibodies have been used in diagnosis for decades. However, the immunological mechanism underlying their generation has only become clear following the identification of T follicular helper (TFH) cells and T follicular regulatory (TFR) cells. TFH cells are instrumental in supporting antibody affinity
Jun Deng, Yunbo Wei, Válter R. Fonseca, Luis Graca, Di Yu   +4 more
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T follicular helper cells in space-time

Nature Reviews Immunology, 2016
T follicular helper (TFH) cells play a crucial part in the development of humoral immunity by controlling the formation of, and the cellular reactions that occur in, germinal centres. Within these organized lymphoid tissue microstructures, B cells proliferate and somatically mutate to produce long-lived, high-affinity plasma cells and memory B cells ...
Hai Qi
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Follicular T helper cells and cutaneous T-cell lymphomas

British Journal of Dermatology, 2022
Abstract Linked Article:  Wang et al. Br J Dermatol 2022; 187:970–980.
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SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation

Science, 2020
SOSTDC1 for germinal center regulation T follicular helper (T FH ) cells are CD4 + T cells that facilitate B cell antibody production and B cell memory responses in the germinal centers (GCs) of lymphoid organs. These activities are in turn restrained by T follicular regulatory (T
Xin Wu, Yun Wang, Rui Huang, Qujing Gai, Haofei Liu, Meimei Shi, Xiang Zhang, Yonglin Zuo, Longjuan Chen, Qiwen Zhao, Yu Shi, Fengchao Wang, Xiaowei Yan, Huiping Lu, Senlin Xu, Xiaohong Yao, Lin Chen, Xia Zhang, Qiang Tian, Ziyan Yang, Bo Zhong, Chen Dong, Yan Wang, Xiu-Wu Bian, Xindong Liu   +24 more
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T follicular helper cells in autoimmune diseases

Journal of Autoimmunity, 2023
T follicular helper (Tfh) cells with the phenotype of mainly expressing surface molecules C-X-C motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting cytokine interleukin-21 (IL-21) and requiring the transcription factor B cell lymphoma 6 (BCL-6) have been recently defined as a new subset of CD4+ T cells.
Xindi Wei, Xiaoyin Niu
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T Follicular Helper Cell Differentiation

Science, 2009
When B cells respond to an infection, they often require help from CD4+ T cells to mount a proper response. It is thought that a subset of CD4+ effector T cells, called T follicular helper cells (TFH), performs this function. Several subsets of effector CD4+ T cells arise, depending on the type of infection, which have distinct transcriptional programs
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