Results 181 to 190 of about 15,025,843 (286)

Harmonizing flow‐based quantification of CD19‐directed CAR‐T cells: Results from a multi‐center interlaboratory comparison

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract CD19‐directed CAR‐T cell therapy has become the standard of care for the treatment of relapsed/refractory LBCL, MCL, FL and BCP‐ALL. Expansion of CAR‐T cells in the peripheral blood (PB) of patients in the first weeks after infusion is an important biomarker for the prediction of therapy response and occurrence of toxicities.
Gerulf Hänel, Veit Bücklein, Carolina Berger, Anita Badbaran, Boris Fehse, Guranda Chitadze, Deniz Nogueira Gezer, Michael Hundemer, Wolfgang Kern, Sarah Klapproth, Ines Peschel‐Schaar, Christiane Siewert, Simon Völkl, Maria Xydia, Thomas Nebe, Michael Spannagl, Marion Subklewe   +16 more
wiley   +1 more source

AhR agonist Ficz modulates T follicular helper cells and ameliorates skin fibrosis in a bleomycin-induced SSc mouse model. [PDF]

J Scleroderma Relat Disord
Zhu X, Chen Y, Qiu C, Wei M, Chen J, Luo B, Qi Q.   +6 more
europepmc   +1 more source

Oogenesis and germinal bed morphology of the brown anole (A. sagrei)

Developmental Dynamics, EarlyView.
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher, Antonia Weberling, Erin J. Vance, Natalia A. Shylo, Katherine Starr, Zoe B. Griffin, Hannah Wilson, Melainia McClain, Florian Hollfelder, Suzannah A. Williams, Thomas J. Sanger, Richard R. Behringer, Paul A. Trainor   +12 more
wiley   +1 more source

Correction: Cholesterol promotes autoimmune pathology through T follicular helper cells. [PDF]

Cell Mol Immunol
Li W, Tsokos GC.
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

The interaction between dendritic cells and T follicular helper cells drives inflammatory bowel disease: a review. [PDF]

Front Immunol
Lv Y, Jin YL, Zhou Z, Liao JB, Zhang ZQ, Tang LY, Xie XH, Wang S, Jin MX, Liu HY.   +9 more
europepmc   +1 more source

Jaw‐specific stem cell dynamics are associated with distinct enamel architecture in mouse incisors

Developmental Dynamics, EarlyView.
Abstract Background The continuously growing mouse incisor serves as a model for stem cell‐driven tooth renewal. Although mice possess maxillary and mandibular incisors, most studies have focused on the mandible. Potential differences in structure and renewal between these serially homologous organs remain insufficiently characterized.
Elias Shahin, Jihan Asmar, Sanako Takano, Jimmy K. Hu, Amnon Sharir   +4 more
wiley   +1 more source

Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus. [PDF]

Cell Rep
Choi SC, Ge Y, Elshikha A, Park YP, Fang C, Joshi MV, Montes de Oca Arena M, Padilla L, Zhu Y, Clapp WL, Sobel ES, Mohamadzadeh M, Morel L.   +12 more
europepmc   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

T cells in ITP: Focus on T follicular helper cells and cytotoxic T cells. [PDF]

Br J Haematol
Audia S, Cooper N.
europepmc   +1 more source