Results 171 to 180 of about 1,267,388 (382)
FlowCyt: A Comparative Study of Deep Learning Approaches for Multi-Class Classification in Flow Cytometry Benchmarking [PDF]
This paper presents FlowCyt, the first comprehensive benchmark for multi-class single-cell classification in flow cytometry data. The dataset comprises bone marrow samples from 30 patients, with each cell characterized by twelve markers. Ground truth labels identify five hematological cell types: T lymphocytes, B lymphocytes, Monocytes, Mast cells, and
arxiv
Bacille Calmette-Guérin infection in the mouse. Regulation of macrophage plasminogen activator by T lymphocytes and specific antigen. [PDF]
Siamon Gordon, Zanvil A. Cohn
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The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang+9 more
wiley +1 more source
Cytotoxic Activity of Human Lymphocytes: Quantitative Analysis of T Cell and K Cell Cytotoxicity, Revealing Enzyme-Like Kinetics [PDF]
Wim P. Zeijlemaker+3 more
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This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Sensitization of T Lymphocytes in Vitro by Syngeneic Macrophages Fed with Tumor Antigens [PDF]
Abraham J. Treves+3 more
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Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray+2 more
wiley +1 more source
Functional Heterogeneity Among the T-Derived Lymphocytes of the Mouse [PDF]
Fred Burns+3 more
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Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham+16 more
wiley +1 more source