Reviewer #2 (Public Review): WASP facilitates tumor mechanosensitivity in T lymphocytes
Srishti Mandal +9 more
openalex +1 more source
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
Editorial: Mechanisms of early intracellular signaling in T lymphocytes. [PDF]
Aguado E +2 more
europepmc +1 more source
Antigen receptors on major histocompatibility complex-restricted T lymphocytes. I. Preparation and characterization of syngeneic antisera against trinitrophenyl-activated T cell blasts and demonstration of their specificity for idiotypes on cytotoxic T lymphocytes. [PDF]
P H Krammer, R Rehberger, Klaus Eichmann
openalex +1 more source
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu +16 more
wiley +1 more source
CD38 promotes LPS-induced innate-like activation and proliferation of CD8<sup>+</sup> T lymphocytes in aged mice. [PDF]
Santiago-Cruz W +6 more
europepmc +1 more source
Correction: Immunodominance of cytotoxic T lymphocyte epitopes co-injected in vivo and modulation by interleukin-12, Vol 26 (11) 1996, 2709-2716 [PDF]
Gérard Eberl +5 more
openalex +1 more source
Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu +12 more
wiley +1 more source

