Results 61 to 70 of about 1,267,388 (382)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Decreased T Cell Levels in Critically Ill Coronavirus Patients: Single-Center, Prospective and Observational Study

Journal of Inflammation Research, 2021
Jingjing Xu,1 Zhiyu Liu,2 Haitao Liu,1 Yunpeng Luo,3 Kai Kang,3 Xueting Li,1 Wei Yang,3 Dongsheng Fei,3 Changsong Wang,1,3 Kaijiang Yu3 1Department of Critical Care Medicine, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province ...
Xu J, Liu Z, Liu H, Luo Y, Kang K, Li X, Yang W, Fei D, Wang C, Yu K   +9 more
doaj  

Generating CAR T cells from tumor-infiltrating lymphocytes

Therapeutic Advances in Vaccines and Immunotherapy, 2021
Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma.
Jane K. Mills, Melissa A. Henderson, Lauren Giuffrida, Pasquale Petrone, Jennifer A. Westwood, Phillip K. Darcy, Paul J. Neeson, Michael H. Kershaw, David E. Gyorki   +8 more
doaj   +1 more source

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer [PDF]

, 2012
A summit on cellular therapy for cancer discussed and presented advances related to the use of adoptive cellular therapy for melanoma and other cancers. The summit revealed that this field is advancing rapidly.
A Lundqvist, A Somers, C Berger, CA Tran, Carolina Berger, Cornelis JM Melief, Daniel J Powell, David F Stroncek, DG Song, DJ Powell Jr, DL Porter, Francesco M Marincola, G Mostoslavsky, GG Kenter, Gustavo Mostoslavsky, J Jin, J Staerk, James R Heath, Jeffrey S Miller, JN Kochenderfer, JN Kochenderfer, John O'Shea, JS Miller, K Takahashi, L Gattinoni, L Gattinoni, L Gattinoni, L Gattinoni, LA Johnson, Luca Gattinoni, M Kalos, M Kalos, M Kalos, Mahendra Rao, Mark E Dudley, Martin A Cheever, ME Dudley, ME Dudley, Michael Kalos, Nicholas P Restifo, P Muranski, Peter Flynn, PF Robbins, RA Morgan, Richard W Childs, SA Rosenberg, Steven A Rosenberg, TS Park, X Wang   +48 more
core   +4 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Discrete and continuum models for the coevolutionary dynamics between CD8+ cytotoxic T lymphocytes and tumour cells [PDF]

arXiv, 2021
We present an individual-based model for the coevolutionary dynamics between CD8+ cytotoxic T lymphocytes (CTLs) and tumour cells. In this model, every cell is viewed as an individual agent whose phenotypic state is modelled by a discrete variable. For tumour cells this variable represents a parameterisation of the antigen expression profiles, while ...
arxiv  

Local CD4+, CD8+ and CD56+ reactions to lung cancer in regard to pathohistological type and clinical stage [PDF]

Medicinski Glasnik, 2011
Aim To determinate the difference of abundance of CD4+, CD8+ and CD56+ bronchoalveolar luid’s lymphocytes and their subpopulations between non- and small cell lung cancer.
Edin Jusufovic, Ermina Iljazovic, Mitja Kosnik, Dragan Keser, Peter Korosec, Edin Zukic, Besim Prnjavorac, Rifat Sejdinović, Ekrem Ajanović   +8 more
doaj  

N-Acetylcysteine as Adjuvant Therapy for COVID-19 – A Perspective on the Current State of the Evidence

Journal of Inflammation Research, 2021
Kon Ken Wong,1,2 Shaun Wen Huey Lee,3– 6 Kok Pim Kua7 1Department of Microbiology and Immunology, Hospital Canselor Tuanku Muhriz UKM, Cheras, Kuala Lumpur, Malaysia; 2Faculty of Medicine, The National University of Malaysia, Cheras, Kuala Lumpur ...
Wong KK, Lee SWH, Kua KP
doaj  

EXPRESSION ASPECTS OF CD16 AND NKG2D RECEPTORS BY NK CELLS, NKT CELLS AND T LYMPHOCYTES OF PERIPHERAL BLOOD ASSOCIATED WITH FEMALE INFERTILITY

Медицинская иммунология, 2019
The increasing incidence of infertility determines relevance of studying the contribution of various cellular factors, including immune cells, to its pathogenesis.
Valentina A Mikhailova, Alina A Davydova, Valeria A Zagaynova, Oksana B. Marko, Edgar R. Mkrtchyan, Aleksandra S. Zhguleva, Olga A. Bakulina, Sergey A. Selkov, Olesya N. Bespalova, Dmitry I. Sokolov   +9 more
doaj   +1 more source

IL-17-Producing Regulatory T lymphocytes – Suppressors or Effectors?

Учёные записки Казанского университета: Серия Естественные науки, 2023
Regulatory T (Treg) lymphocytes are a T helper population that controls the intensity of the immune response and maintains immune tolerance by selectively suppressing the activity of effector T lymphocytes.
E. M. Kuklina, N. S. Glebezdina
doaj   +1 more source