Results 81 to 90 of about 11,697,514 (297)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

N-Acetylcysteine as Adjuvant Therapy for COVID-19 – A Perspective on the Current State of the Evidence

open access: yesJournal of Inflammation Research, 2021
Kon Ken Wong,1,2 Shaun Wen Huey Lee,3– 6 Kok Pim Kua7 1Department of Microbiology and Immunology, Hospital Canselor Tuanku Muhriz UKM, Cheras, Kuala Lumpur, Malaysia; 2Faculty of Medicine, The National University of Malaysia, Cheras, Kuala Lumpur ...
Wong KK, Lee SWH, Kua KP
doaj  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

La synapse immunologique : Une plate-forme de signalisation dynamique pour l’activation des lymphocytes T

open access: yes, 2014
International audienceAdaptive immune responses are initiated by the recognition of antigens by T lymphocytes. Antigen recognition triggers the generation of immunological synapses. These are dynamic and finely organized cell-cell contacts formed between
Jérôme Bouchet   +3 more
core   +1 more source

МЕСТО РРСС В НОЗОПРОФИЛЕ ИНФЕКЦИОННОЙ ПАТОЛОГИИ СВИНЕЙ В РОСТОВСКОЙ ОБЛАСТИ

open access: yesВетеринарная патология, 2010
Infectious pathology of pigs in the Rostov region is represented mainly bacterial diseases (52,8% of the total infectious diseases). However, the bacteria, as is usually secondary pathogens to cause clinical picture against viral disease.

doaj  

Decreased T Cell Levels in Critically Ill Coronavirus Patients: Single-Center, Prospective and Observational Study

open access: yesJournal of Inflammation Research, 2021
Jingjing Xu,1 Zhiyu Liu,2 Haitao Liu,1 Yunpeng Luo,3 Kai Kang,3 Xueting Li,1 Wei Yang,3 Dongsheng Fei,3 Changsong Wang,1,3 Kaijiang Yu3 1Department of Critical Care Medicine, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province ...
Xu J   +9 more
doaj  

FUNCTIONAL AORTIC STIFFNESS:ROLE OF CD4+ T LYMPHOCYTES

open access: yesFrontiers in Physiology, 2015
The immune system is suggested to be essential in vascular remodeling and stiffening. To study the dependence upon lymphocytes in vascular stiffening, we compared an angiotensin II-model of vascular stiffening in normal C57BL/6J mice with lymphocyte ...
Beenish A. Majeed   +5 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Allorecognition by T lymphocytes and allograft rejection

open access: yesFrontiers in Immunology, 2016
Recognition of donor antigens by recipient T cells in secondary lymphoid organs initiates the adaptive inflammatory immune response leading to the rejection of allogeneic transplants.
Gilles Benichou   +2 more
doaj   +1 more source

Superoxide dismutase activity of T lymphocytes and non‐T lymphocytes [PDF]

open access: yesFEBS Letters, 1979
Kobayashi, Yohnosuke   +4 more
openaire   +2 more sources

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