Results 11 to 20 of about 318 (92)

Natural variability of trace-amine associated receptors in wild meerkats [PDF]

Frontiers in Zoology
Background The study of olfaction as a sensory modality has been relatively neglected in comparison to other sensory cues, particularly in wildlife research.
Johannes Fähnle, Kerstin Wilhelm, Benedikt Wiese, Marta Manser, Tim Clutton-Brock, Simone Sommer, Nadine Müller-Klein   +6 more
doaj   +12 more sources

A region of 35 kb containing the trace amine associate receptor 6 (TAAR6) gene is associated with schizophrenia in the Irish study of high-density schizophrenia families [PDF]

Molecular Psychiatry, 2007
The TAAR6 gene has been previously associated with schizophrenia in 192 pedigrees of European and African ancestry. To replicate these findings we performed an association study of TAAR6 in 265 pedigrees of the Irish Study of High-Density Schizophrenia Families (ISHDSF).
Joseph L. McClay, Francis A O'Neill, Po-Hsiu Kuo   +2 more
exaly   +7 more sources

TAAR8 in the Brain: Implications for Dopaminergic Function, Neurogenesis, and Behavior [PDF]

Biomedicines
Background/Objectives: G protein-coupled trace amine-associated receptors (TAARs) belong to a family of biogenic amine-sensing receptors. TAAR1 is the best-investigated receptor of this family, and TAAR1 agonists are already being tested in clinical ...
Taisiia S. Shemiakova, Alisa A. Markina, Evgeniya V. Efimova, Ramilya Z. Murtazina, Anna B. Volnova, Aleksandr A. Veshchitskii, Elena I. Leonova, Raul R. Gainetdinov   +7 more
doaj   +4 more sources

TAAR9 knockout increases hippocampal serotonin and alters grooming behavior in rats [PDF]

Frontiers in Pharmacology
IntroductionDespite their association with brain disorders, the neurophysiological roles of the trace amine-associated receptors remain poorly understood.
Ilya S. Zhukov, Ilya S. Zhukov, Inessa V. Karpova, Ramilya Z. Murtazina, Yazen Alnefeesi, Olga M. Korenkova, Ilia Yu. Tissen, Svetlana A. Palchikova, Lydia A. Tokareva, Sarng S. Pyurveev, Petr D. Shabanov, Larisa G. Kubarskaya, Larisa G. Kubarskaya, Mikhail A. Rozhko, Ekaterina B. Zernova, Ekaterina A. Zolotoverkhaja, Anna B. Volnova, Allan V. Kalueff, Natalia V. Alenina, Raul R. Gainetdinov, Raul R. Gainetdinov   +20 more
doaj   +5 more sources

The Trace Amine Associated Receptor (TAAR6) gene is not associated with schizophrenia in the Irish Case-Control Study of Schizophrenia (ICCSS) sample [PDF]

Schizophrenia Research, 2008
To replicate previous association between TAAR6 and schizophrenia, including our own finding in the Irish Study of High Density Schizophrenia Families (ISHDSF) sample, we genotyped 12 single nucleotide polymorphisms (SNPs) in the Irish Case-Control Study
V. Vladimirov, B. Maher, B. Wormley, F. O'Neill, D. Walsh, K. Kendler, B. Riley   +6 more
semanticscholar   +5 more sources

Expression Pattern of Trace Amine-Associated Receptors during Differentiation of Human Pluripotent Stem Cells to Dopaminergic Neurons. [PDF]

Int J Mol Sci, 2023
Trace amine-associated receptors (TAARs), which were discovered only in 2001, are known to be involved in the regulation of a spectrum of neuronal processes and may play a role in the pathogenesis of a number of neuropsychiatric diseases, such as ...
Katolikova NV, Vaganova AN, Shafranskaya DD, Efimova EV, Malashicheva AB, Gainetdinov RR.   +5 more
europepmc   +3 more sources

TAAR6 variation effect on clinic presentation and outcome in a sample of schizophrenic in-patients: An open label study

European Psychiatry, 2008
AbstractWe recently reported an association betweenTAAR6(trace amine associated receptor 6 gene) variations and schizophrenia (SZ). We now report an association of a set ofTAAR6variations and clinical presentation and outcome in a sample of 240 SZ Korean patients.
C. Pae, A. Drago, Jung-Jin Kim, A. Patkar, T. Jun, C. Lee, L. Mandelli, D. De Ronchi, I. Paik, A. Serretti   +9 more
semanticscholar   +5 more sources

Molecular Variants in Human Trace Amine-Associated Receptors and Their Implications in Mental and Metabolic Disorders. [PDF]

Cell Mol Neurobiol, 2020
We provide a comprehensive review of the available evidence on the pathophysiological implications of genetic variants in the human trace amine-associated receptor (TAAR) superfamily.
Rutigliano G, Zucchi R.
europepmc   +4 more sources

Multiancestry Genome-Wide Association Study of Early Childhood Caries. [PDF]

J Dent Res
Early childhood caries (ECC) is the most common noncommunicable childhood disease—an important health problem with known environmental and social/behavioral influences lacking consensus genetic risk loci.
Shrestha P, Graff M, Gu Y, Wang Y, Avery CL, Ginnis J, Simancas-Pallares MA, Ferreira Zandoná AG, Alotaibi RN, Orlova E, Ahn HS, Nguyen KN, Highland HM, Lin DY, Preisser JS, Slade GD, Marazita ML, North KE, Divaris K.   +18 more
europepmc   +5 more sources

Genetic Signatures of Positive Selection in Human Populations Adapted to High Altitude in Papua New Guinea. [PDF]

Genome Biol Evol
Papua New Guinea (PNG) hosts distinct environments mainly represented by the ecoregions of the Highlands and Lowlands that display increased altitude and a predominance of pathogens, respectively. Since its initial peopling approximately 50,000 years ago,
González-Buenfil R, Vieyra-Sánchez S, Quinto-Cortés CD, Oppenheimer SJ, Pomat W, Laman M, Cervantes-Hernández MC, Barberena-Jonas C, Auckland K, Allen A, Allen S, Phipps ME, Huerta-Sanchez E, Ioannidis AG, Mentzer AJ, Moreno-Estrada A.   +15 more
europepmc   +4 more sources