Results 111 to 120 of about 1,684 (129)
Antimicrobial Activities of Indole Alkaloids from Tabernaemontana catharinensis
Natural Product Communications, 2011 Tabernaemontana catharinensis root bark ethanol extract, EB2 fraction and the MMV alkaloid (12-methoxy-4-methylvoachalotine) were evaluated for their antimicrobial activities. T.
Ana Lúcia Fachin +2 more
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Planta Medica, 2020
AbstractPlants produce a high diversity of metabolites that can act as regulators of cholinergic dysfunction. Among plants, the potential of species of the genus Tabernaemontana to treat neurological disorders has been linked to iboga-type alkaloids that are biosynthesized by those species.
Bruno Musquiari +8 more
openaire +2 more sources
AbstractPlants produce a high diversity of metabolites that can act as regulators of cholinergic dysfunction. Among plants, the potential of species of the genus Tabernaemontana to treat neurological disorders has been linked to iboga-type alkaloids that are biosynthesized by those species.
Bruno Musquiari +8 more
openaire +2 more sources
Phytochemical constituents and in vitro antioxidant capacity of Tabernaemontana catharinensis A. DC
Free Radicals and Antioxidants, 2013Abstract Introduction Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation, and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. In this present study we determined the in vitro antioxidant capacity and quantified of total phenolics, flavonoids, tannins
Aline Augusti Boligon +6 more
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Natural Product Research, 2012
The essential oils obtained by hydrodistillation from the leaves of Tabernaemontana catharinensis had their composition analysed by GC-MS. A total of 18 substances were identified, consisting of a complex mixture of sesquiterpenes (83.52%), monoterpenes (5.46%) and triterpenes (4.56%).
Aline Augusti, Boligon +7 more
openaire +2 more sources
The essential oils obtained by hydrodistillation from the leaves of Tabernaemontana catharinensis had their composition analysed by GC-MS. A total of 18 substances were identified, consisting of a complex mixture of sesquiterpenes (83.52%), monoterpenes (5.46%) and triterpenes (4.56%).
Aline Augusti, Boligon +7 more
openaire +2 more sources
Bioorganic Chemistry, 2019
Plant compounds have been identified as new drug prototypes. In this line, this work aimed to isolate the indole alkaloid affinisine from Tabernaemontana catharinensis and test its antitumor activity. The alkaloid was isolated by silica gel open column chromatography from the ethanolic extract of the stem of T. catharinensis.
Pauline, Fagundes Rosales +8 more
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Plant compounds have been identified as new drug prototypes. In this line, this work aimed to isolate the indole alkaloid affinisine from Tabernaemontana catharinensis and test its antitumor activity. The alkaloid was isolated by silica gel open column chromatography from the ethanolic extract of the stem of T. catharinensis.
Pauline, Fagundes Rosales +8 more
openaire +2 more sources
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2004
The high mortality caused by Crotalus durissus terrificus snake venom is mainly due to crotoxin, which acts on the neuromuscular junction inhibiting the mechanism mediating acetylcholine release, thus leading to motor and respiratory paralysis and subsequently to animal death.
Lucilene, de Almeida +7 more
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The high mortality caused by Crotalus durissus terrificus snake venom is mainly due to crotoxin, which acts on the neuromuscular junction inhibiting the mechanism mediating acetylcholine release, thus leading to motor and respiratory paralysis and subsequently to animal death.
Lucilene, de Almeida +7 more
openaire +2 more sources
Phytochemistry Letters, 2021
Abstract Latex from Tabernaemontana catharinensis contains synthesized bioactive compounds known as monoterpenoid indole alkaloids (MIAs). Such compounds have several biological activities, including as cholinesterase inhibitors, and have analgesic, anti-inflammatory, bactericidal, antileishmanial, antitumoral andestrogenic properties, as well as ...
Bruna Higashi +5 more
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Abstract Latex from Tabernaemontana catharinensis contains synthesized bioactive compounds known as monoterpenoid indole alkaloids (MIAs). Such compounds have several biological activities, including as cholinesterase inhibitors, and have analgesic, anti-inflammatory, bactericidal, antileishmanial, antitumoral andestrogenic properties, as well as ...
Bruna Higashi +5 more
openaire +1 more source
Journal of Ethnopharmacology, 2016
Tabernaemontana catharinensis (Apocynaceae) is a medicinal plant used for the treatment of painful and inflammatory disorders. Here, we investigated the antinociceptive potential of the ethyl acetate fraction (Eta) from T. catharinensis leaves and assessed its toxic effects in mice to validate its popular use.Adult male Swiss mice (30-35g) were used ...
Evelyne, da Silva Brum +7 more
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Tabernaemontana catharinensis (Apocynaceae) is a medicinal plant used for the treatment of painful and inflammatory disorders. Here, we investigated the antinociceptive potential of the ethyl acetate fraction (Eta) from T. catharinensis leaves and assessed its toxic effects in mice to validate its popular use.Adult male Swiss mice (30-35g) were used ...
Evelyne, da Silva Brum +7 more
openaire +2 more sources