Results 21 to 30 of about 4,388 (281)
Pharmaceutics, 2021 In pharmaceutical manufacturing, the utmost aim is reliably producing high quality products. Simulation approaches allow virtual experiments of processes in the planning phase and the implementation of digital twins in operation.
Niels Lasse Martin +5 more
doaj +1 more source
Applied Sciences, 2022 Following the paradigm shift in the pharmaceutical industry from batch to continuous production, additional instrumentation and revision of control strategies to optimize material flow throughout the downstream processes are required.
Mihaela Ghita +4 more
doaj +1 more source
Ars Pharmaceutica, 2020 Objective: The aim of this study was to evaluate the performance of maize starch as a multifunctional excipient in metronidazole tablet formulation. Methods: Metronidazole tablets were prepared by wet granulation containing maize starch as diluent (40 %)
Yonni Eshovo Apeji +5 more
doaj +1 more source
Instrumentation of tableting machines : high speed compaction investigation through simulation and radial die-wall pressure monitoring [PDF]
, 2011 Background: The complexity of the compaction process specially with using high-speed tablet presses necessitates the use of robust monitoring tools during the process.
Abdel-Hamid Abd-Rabo, Sameh Mohamed
core +1 more source
Pharmaceutics, 2021 The purpose of this work is to simulate the powder compaction of pharmaceutical materials at the microscopic scale in order to better understand the interplay of mechanical forces between particles, and to predict their compression profiles by ...
Kostas Giannis +3 more
doaj +1 more source
Powder Technology and Pharmaceutical Development: Particle Size and Particle Adhesion
KONA Powder and Particle Journal, 2013 Both the FDA (U.S. Food and Drug Administration) and ICH (International Conference on Harmonisation) have urged the incorporation of Quality by Design (QbD)1) into the manufacture of pharmaceutical products2).The performance of many pharmaceutical ...
Frank M. Etzler, Mohammad Nasir Uddin
doaj +1 more source
Opposing Effects of Additives in Dry Milling and Tableting of Organic Particles
Pharmaceutics, 2021 Applying additives and excipients during the dry processing of fine particles is a common measure to control the particle–particle interactions, to specifically influence the powder properties and to enhance the process efficiency or product quality.
Lina Miethke +3 more
doaj +1 more source
Impact of Powder Properties on the Rheological Behavior of Excipients
Pharmaceutics, 2021 With the emergence of quality by design in the pharmaceutical industry, it becomes imperative to gain a deeper mechanistic understanding of factors impacting the flow of a formulation into tableting dies. Many flow characterization techniques are present,
Pauline H. M. Janssen +4 more
doaj +1 more source
Experimental Elucidation of Templated Crystallization and Secondary Processing of Peptides
Pharmaceutics, 2023 The crystallization of peptides offers a sustainable and inexpensive alternative to the purification process. In this study, diglycine was crystallised in porous silica, showing the porous templates’ positive yet discriminating effect.
Vivek Verma +3 more
doaj +1 more source