Results 21 to 30 of about 7,267 (291)

Performance evaluation of maize starch as a multifunctional excipient in metronidazole tablet formulation

open access: yesArs Pharmaceutica, 2020
Objective: The aim of this study was to evaluate the performance of maize starch as a multifunctional excipient in metronidazole tablet formulation. Methods: Metronidazole tablets were prepared by wet granulation containing maize starch as diluent (40 %)
Yonni Eshovo Apeji   +5 more
doaj   +1 more source

Lubricant sensitivity in function of paddle movement in the forced feeder of a high-speed tablet press [PDF]

open access: yes, 2016
Context: The negative impact of magnesium stearate (MgSt) on the hardness of tablets is a well-known phenomenon, but the influence of paddle movement in the forced feeder on the lubricant effect during tablet compression is often neglected.
Peeters, Elisabeth   +3 more
core   +2 more sources

Modeling of High-Density Compaction of Pharmaceutical Tablets Using Multi-Contact Discrete Element Method

open access: yesPharmaceutics, 2021
The purpose of this work is to simulate the powder compaction of pharmaceutical materials at the microscopic scale in order to better understand the interplay of mechanical forces between particles, and to predict their compression profiles by ...
Kostas Giannis   +3 more
doaj   +1 more source

Continuous direct compression as manufacturing platform for sustained release tablets [PDF]

open access: yes, 2017
This study presents a framework for process and product development on a continuous direct compression manufacturing platform. A challenging sustained release formulation with high content of a poorly flowing low density drug was selected.
Cunningham, C.   +7 more
core   +1 more source

Review on Tablet in Tablet techniques [PDF]

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2020
Abstract Background Among all available dosage form, tablet is most widely used because of its stability and patient acceptability. The better aesthetic quality like color, texture, mouth feel, and taste masking depended on film and sugar coatings, so the coating is an important part in the formulation of the tablet.
Sachin S. Gaikwad, Sanjay J. Kshirsagar
openaire   +2 more sources

Reduction of tablet weight variability by optimizing paddle speed in the forced feeder of a high-speed rotary tablet press [PDF]

open access: yes, 2014
Context: Tableting is a complex process due to the large number of process parameters that can be varied. Knowledge and understanding of the influence of these parameters on the final product quality is of great importance for the industry, allowing ...
De Beer, Thomas   +3 more
core   +1 more source

Comparative analysis of co-processed starches prepared by three different methods [PDF]

open access: yes, 2015
Co-processing is currently of interest in the generation of high-functionality excipients for tablet formulation. In the present study, comparative analysis of the powder and tableting properties of three co-processed starches prepared by three different
Adeoye, O., Alebiowu, G.   +50 more
core   +5 more sources

Powder Technology and Pharmaceutical Development: Particle Size and Particle Adhesion

open access: yesKONA Powder and Particle Journal, 2013
Both the FDA (U.S. Food and Drug Administration) and ICH (International Conference on Harmonisation) have urged the incorporation of Quality by Design (QbD)1) into the manufacture of pharmaceutical products2).The performance of many pharmaceutical ...
Frank M. Etzler, Mohammad Nasir Uddin
doaj   +1 more source

Opposing Effects of Additives in Dry Milling and Tableting of Organic Particles

open access: yesPharmaceutics, 2021
Applying additives and excipients during the dry processing of fine particles is a common measure to control the particle–particle interactions, to specifically influence the powder properties and to enhance the process efficiency or product quality.
Lina Miethke   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy