Results 31 to 40 of about 2,257 (250)

How spherical crystallization improves direct tableting properties: a review [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2012
Direct tableting has been renewed as a preferable process by simply mixing and compressing powder to save time and cost in comparison with granule tableting.
Maryam Maghsoodi
doaj  

The Challenge of Die Filling in Rotary Presses—A Systematic Study of Material Properties and Process Parameters

open access: yesPharmaceutics, 2020
For the efficient and safe production of pharmaceutical tablets, a deep process understanding is of high importance. An essential process step during tableting is the die filling, as it is responsible for a consistent tablet weight and drug content ...
Ann Kathrin Schomberg   +2 more
doaj   +1 more source

Partial Least Squares Regression-Based Robust Forward Control of the Tableting Process

open access: yesPharmaceutics, 2020
In this study, we established a robust feed-forward control model for the tableting process by partial least squares regression using the near-infrared (NIR) spectra and physical attributes of the granules to be compressed.
Yusuke Hattori   +2 more
doaj   +1 more source

Finite Element Analysis and Modeling in Pharmaceutical Tableting

open access: yesPharmaceutics, 2022
Finite element analysis (FEA) is a computational method providing numerical solutions and mathematical modeling of complex physical phenomena that evolve during compression tableting of pharmaceutical powders. Since the early 2000s, FEA has been utilized
Ioannis Partheniadis   +2 more
doaj   +1 more source

Twin Screw Granulation: An Investigation of the Effect of Barrel Fill Level

open access: yesPharmaceutics, 2018
This paper focuses on investigating the influence of varying barrel fill levels on the mean residence time, granule properties (median size, size distribution, and shape), and tensile strength of tablets.
Sushma V. Lute   +2 more
doaj   +1 more source

Application of Machine-Learning Algorithms for Better Understanding of Tableting Properties of Lactose Co-Processed with Lipid Excipients

open access: yesPharmaceutics, 2021
Co-processing (CP) provides superior properties to excipients and has become a reliable option to facilitated formulation and manufacturing of variety of solid dosage forms.
Jelena Djuris   +5 more
doaj   +1 more source

Effect of Compaction Pressure on the Enzymatic Activity of Pancreatin in Directly Compressible Formulations

open access: yesPharmaceutics, 2023
Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated.
Daniel Zakowiecki   +6 more
doaj   +1 more source

Design of Agglomerated Crystals of Ibuprofen During Crystallization: Influence of Surfactant [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2011
Objective(s)Ibuprofen is a problematic drug in tableting, and dissolution due to its poor solubility, hydrophobicity, and tendency to stick to surface.
Maryam Maghsoodi, Leila Barghi
doaj  

Twin Screw Granulation: Effects of Properties of Primary Powders

open access: yesPharmaceutics, 2018
Lactose and mannitol are some of the most commonly used powders in the pharmaceutical industry. The limited research published so far highlights the effects of process and formulation parameters on the properties of the granules and the tablets produced ...
Sushma V. Lute   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

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