Results 31 to 40 of about 7,267 (291)
Impact of Powder Properties on the Rheological Behavior of Excipients
Pharmaceutics, 2021 With the emergence of quality by design in the pharmaceutical industry, it becomes imperative to gain a deeper mechanistic understanding of factors impacting the flow of a formulation into tableting dies. Many flow characterization techniques are present,
Pauline H. M. Janssen +4 more
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Influence of extended dwell time during pre- and main compression on the properties of ibuprofen tablets [PDF]
, 2018 The low melting point, poor flow, physico-mechanical properties (particle size distribution, shape, particle surface roughness) and deformation mechanism of ibuprofen in combination with its high dose in tablets all contribute to the problems observed ...
De Beer, Thomas +5 more
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A classification system for tableting behaviors of binary powder mixtures
Asian Journal of Pharmaceutical Sciences, 2016 The ability to predict tableting properties of a powder mixture from individual components is of both fundamental and practical importance to the efficient formulation development of tablet products.
Changquan Calvin Sun
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Pharmaceutics, 2020 Paddle feeders are devices commonly used in rotary tablet presses to facilitate constant and efficient die filling. Adversely, the shear stress applied by the rotating paddles is known to affect the bulk properties of the processed powder dependent on ...
Daniel Puckhaber +3 more
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Experimental Elucidation of Templated Crystallization and Secondary Processing of Peptides
Pharmaceutics, 2023 The crystallization of peptides offers a sustainable and inexpensive alternative to the purification process. In this study, diglycine was crystallised in porous silica, showing the porous templates’ positive yet discriminating effect.
Vivek Verma +3 more
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Correlation of Solid Dosage Porosity and Tensile Strength with Acoustically Extracted Mechanical Properties [PDF]
, 2018 Currently, the compressed tablet and its oral administration is the most popular drug delivery modality in medicine. The accurate porosity and tensile strength characterization of a tablet design is vital for predicting its performance such as ...
Cetinkaya, Centin +5 more
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Studies on tableting properties of lactose. Part III. The consolidation behaviour of sieve fractions of crystalline a-lactose\ud monohydrate [PDF]
, 1986 The consolidation and compaction behaviour of sieve fractions of crystalline α-lactose monohydrate were studied. From mercury porosimetry measurements tablet pore surface areas were derived.
Boer, A.H. de +5 more
core +3 more sources
eXPRESS Polymer Letters, 2018 Polymer-based electrospun amorphous solid dispersions (ASDs) were prepared and investigated from pharmaceutical application point of view. Spironolactone (SPIR) was used as model drug mixed in various concentrations with polymers suitable for fibre ...
E. Szabo +10 more
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Compaction Properties of Particulate Proteins in Binary Powder Mixtures with Common Excipients
Pharmaceutics, 2023 The increasing interest in protein- and peptide-based oral pharmaceuticals has culminated in the first protein-based products for oral delivery becoming commercially available.
Else Holmfred +2 more
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Pharmaceutics, 2020 For the efficient and safe production of pharmaceutical tablets, a deep process understanding is of high importance. An essential process step during tableting is the die filling, as it is responsible for a consistent tablet weight and drug content ...
Ann Kathrin Schomberg +2 more
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