Results 41 to 50 of about 4,388 (281)
Twin Screw Granulation: An Investigation of the Effect of Barrel Fill Level
Pharmaceutics, 2018 This paper focuses on investigating the influence of varying barrel fill levels on the mean residence time, granule properties (median size, size distribution, and shape), and tensile strength of tablets.
Sushma V. Lute +2 more
doaj +1 more source
Pharmaceutics, 2023 Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated.
Daniel Zakowiecki +6 more
doaj +1 more source
Design of Agglomerated Crystals of Ibuprofen During Crystallization: Influence of Surfactant [PDF]
Iranian Journal of Basic Medical Sciences, 2011 Objective(s)Ibuprofen is a problematic drug in tableting, and dissolution due to its poor solubility, hydrophobicity, and tendency to stick to surface.
Maryam Maghsoodi, Leila Barghi
doaj
Twin Screw Granulation: Effects of Properties of Primary Powders
Pharmaceutics, 2018 Lactose and mannitol are some of the most commonly used powders in the pharmaceutical industry. The limited research published so far highlights the effects of process and formulation parameters on the properties of the granules and the tablets produced ...
Sushma V. Lute +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz +6 more
wiley +1 more source
Multivariate statistical modelling of the pharmaceutical process of wet granulation and tableting [PDF]
, 1997 Wet granulation in high-shear mixers is a process of particle size enlargement much used in the pharmaceutical industry to improve the tableting properties of powder mixtures, such as flowability and compactibility, necessary for the large scale ...
Westerhuis, Johannes Arnold
core +3 more sources
Pharmaceutics, 2019 In-die compression analysis is an effective method for the characterization of powder compressibility. However, physically unreasonable apparent solid fractions above one or apparent in-die porosities below zero are often calculated for higher ...
Isabell Wünsch +4 more
doaj +1 more source
Pharmaceutics, 2023 Designing a robust direct compression (DC) formulation for an active pharmaceutical ingredient (API) with poor flow and compaction properties at a high API load is challenging.
Majed Alrobaian +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Multi objective optimization approach for enhancing flexibility of a pharmaceutical tableting process [Abstract]
Brahim Benyahia (1258056) +1 more
core +3 more sources