Results 41 to 50 of about 7,179 (272)
Finite Element Analysis and Modeling in Pharmaceutical Tableting
Pharmaceutics, 2022 Finite element analysis (FEA) is a computational method providing numerical solutions and mathematical modeling of complex physical phenomena that evolve during compression tableting of pharmaceutical powders. Since the early 2000s, FEA has been utilized
Ioannis Partheniadis +2 more
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Partial Least Squares Regression-Based Robust Forward Control of the Tableting Process
Pharmaceutics, 2020 In this study, we established a robust feed-forward control model for the tableting process by partial least squares regression using the near-infrared (NIR) spectra and physical attributes of the granules to be compressed.
Yusuke Hattori +2 more
doaj +1 more source
Pharmaceutics, 2021 Co-processing (CP) provides superior properties to excipients and has become a reliable option to facilitated formulation and manufacturing of variety of solid dosage forms.
Jelena Djuris +5 more
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Twin Screw Granulation: An Investigation of the Effect of Barrel Fill Level
Pharmaceutics, 2018 This paper focuses on investigating the influence of varying barrel fill levels on the mean residence time, granule properties (median size, size distribution, and shape), and tensile strength of tablets.
Sushma V. Lute +2 more
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Pharmaceutics, 2023 Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated.
Daniel Zakowiecki +6 more
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Influence of extended dwell time during pre- and main compression on the properties of ibuprofen tablets [PDF]
, 2018 The low melting point, poor flow, physico-mechanical properties (particle size distribution, shape, particle surface roughness) and deformation mechanism of ibuprofen in combination with its high dose in tablets all contribute to the problems observed ...
De Beer, Thomas +5 more
core +1 more source
Twin Screw Granulation: Effects of Properties of Primary Powders
Pharmaceutics, 2018 Lactose and mannitol are some of the most commonly used powders in the pharmaceutical industry. The limited research published so far highlights the effects of process and formulation parameters on the properties of the granules and the tablets produced ...
Sushma V. Lute +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Pharmaceutics, 2019 In-die compression analysis is an effective method for the characterization of powder compressibility. However, physically unreasonable apparent solid fractions above one or apparent in-die porosities below zero are often calculated for higher ...
Isabell Wünsch +4 more
doaj +1 more source
Downstream processing from hot-melt extrusion towards tablets : a quality by design approach [PDF]
, 2017 Since the concept of continuous processing is gaining momentum in pharmaceutical manufacturing, a thorough understanding on how process and formulation parameters can impact the critical quality attributes (CQA) of the end product is more than ever ...
Bostijn, Nils +9 more
core +2 more sources