Osteogenic Small Molecule FK506 for Enhanced Bone Formation in a Rabbit Ankle Fusion Model
Journal of Orthopaedic Research, EarlyView.ABSTRACT Non‐union remains a significant complication following ankle fusion procedures, underscoring the need for effective osteogenic adjuvants to improve boney healing and fusion outcomes. This study investigates the osteogenic potential of FK506 (Tacrolimus), both in vitro and in vivo, for enhanced ankle fusion.
Nicholas Huffman +6 more
wiley +1 more source
Update on the clinical utility of once-daily tacrolimus in the management of transplantation
Drug Design, Development and Therapy, 2014 Maria Aurora Posadas Salas, Titte R Srinivas Division of Nephrology and Hypertension, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA Abstract: Adherence to immunosuppression and minimizing variability in drug exposure ...
Posadas Salas MA, Srinivas TR
doaj
Tacrolimus and minidose methotrexate for prevention of acute graft- versus-host disease after matched unrelated donor marrow transplantation [PDF]
, 1996 Donna Przepiorka +16 more
openalex +1 more source
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Inflammatory bowel diseases (IBD) require effective therapies to prevent morbidity and maintain quality of life. The introduction of biologic agents, beginning with monoclonal antibodies targeting tumor necrosis factor (TNF) alpha, has launched a new era of advancements that have markedly improved short‐ and long‐term outcomes of Crohn's ...
Lina M. Felipez +7 more
wiley +1 more source
Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)
ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang +3 more
wiley +1 more source
Spontaneous Resolution of Delusional Infestation Upon Eliminating Social Isolation: A Case Report
JEADV Clinical Practice, EarlyView.ABSTRACT Delusional infestation (DI) is a psychiatric condition involving a false belief of parasitic infection. A 79‐year‐old woman with persistent pruritus and scabies delusion refused antipsychotics but improved after relocating to assisted living.
Veranca Shah, Jesse J. Keller
wiley +1 more source
Pantoprazole and cyclosporine or tacrolimus [PDF]
Alimentary Pharmacology & Therapeutics, 2001 Schwrer, H. +3 more
openaire +4 more sources
Combination Therapy with Oral Tacrolimus (FK506) and Azathioprine or 6-Mercaptopurine for Treatment-Refractory Crohnʼs Disease Perianal Fistulae [PDF]
, 1999 Philip W. Lowry +3 more
openalex +1 more source
Efficacy of Apremilast in Refractory Genital Psoriasis: A Retrospective Case Series
JEADV Clinical Practice, EarlyView.ABSTRACT Background Genital pustular psoriasis is a rare and often underdiagnosed condition that can severely affect physical comfort, quality of life and psychological well‐being. It can be particularly challenging to manage, often requiring systemic therapies due to its potential unresponsiveness to conventional topical treatment.
Jonathan Krygier +2 more
wiley +1 more source
Revisiting the nature and pharmacodynamics of tacrolimus metabolites
Pharmacological ResearchThe toxicity of tacrolimus metabolites and their potential pharmacodynamic (PD) interactions with tacrolimus might respectively explain the surprising combination of higher toxicity and lower efficacy of tacrolimus despite normal blood concentrations ...
Rudy Mevizou +12 more
doaj +1 more source