Results 81 to 90 of about 82,830 (185)

A Case of Tumid Lupus Erythematosus Successfully Treated with Topical Tacrolimus and Hydrocortisone 17-Butyrate [PDF]

Tumid lupus erythematosus is an uncommon subtype of chronic cutaneous lupus erythematosus. Hereby, we report a 36-year-old male patient with tumid lupus erythematosus who presented with erythematous papules and plaques on the face and neck who showed ...
Funda Tamer, İrem Özdemir, Özlem Erdem, Betül Öğüt   +3 more
core   +1 more source

Revisiting the nature and pharmacodynamics of tacrolimus metabolites

Pharmacological Research
The toxicity of tacrolimus metabolites and their potential pharmacodynamic (PD) interactions with tacrolimus might respectively explain the surprising combination of higher toxicity and lower efficacy of tacrolimus despite normal blood concentrations ...
Rudy Mevizou, Hassan Aouad, François-Ludovic Sauvage, Hélène Arnion, Emilie Pinault, Jean-Sébastien Bernard, Gildas Bertho, Nicolas Giraud, Rodolphe Alves de Sousa, Adolfo Lopez-Noriega, Florent Di Meo, Mélanie Campana, Pierre Marquet   +12 more
doaj   +1 more source

[Safety of treatment with tacrolimus ointment for anterior segment inflammatory diseases]

, 2009
BACKGROUND: The off-label use of topical tacrolimus (Protopic) for inflammatory external eye diseases is gaining popularity. However, there are no reports on the safety profile of this new treatment option.
Thiel, M A, Wyrsch, S, Becht, C N
core   +1 more source

Drug–drug interaction between tacrolimus and caspofungin in Chinese kidney transplant patients with different genotypes

Therapeutic Advances in Drug Safety
Background: The effect of drug–drug interaction between tacrolimus and caspofungin on the pharmacokinetics of tacrolimus in different CYP3A5 genotypes has not been reported in previous studies.
Yundi Zhang, Bowen Shen, Yue Li, Huiying Zong, Xiaoming Zhang, Xiaohong Cao, Fengxi Liu, Yan Li   +7 more
doaj   +1 more source

Comparing tacrolimus level monitoring in peripheral blood mononuclear cells and whole blood within one year after kidney transplantation: a single-center, prospective, observational study

Frontiers in Pharmacology
BackgroundTacrolimus, a key immunosuppressant for kidney transplant recipients, is traditionally monitored through whole-blood trough concentrations. However, this approach may not accurately reflect lymphocyte tacrolimus levels, limiting its predictive ...
Jia You, Jia You, Jia You, Rui Chen, Rui Chen, Yuhui Chai, Xue Wang, Wenmin Xie, Yunyun Yang, Kaile Zheng, Kaile Zheng, Kaile Zheng, Lizhi Chen, Zhuo Wang, Xuebin Wang, Xuebin Wang, Xuebin Wang   +16 more
doaj   +1 more source

Efficacy and safety of low-dose topical tacrolimus in vernal keratoconjunctivitis

, 2016
Samir S Shoughy,1 Mahmoud O Jaroudi,1 Khalid F Tabbara1–3 1The Eye Center and The Eye Foundation for Research in Ophthalmology, 2Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 3Wilmer Ophthalmological
Jaroudi MO, Tabbara KF, Shoughy SS
core  

Tacrolimus treatment in women with repeated implantation failures

Reproductive Medicine and Biology
Background Tacrolimus is an immunosuppressive drug that works as a calcineurin inhibitor to improve the reproductive outcomes for women who have experienced multiple implantation failures (RIF) and show elevated type 1 helper T (Th1)/Th2 cell ratios ...
Koji Nakagawa, Rikikazu Sugiyama
doaj   +1 more source

New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients

, 2017
Yu Kyong Kim,1 Anhye Kim,1,2 Shin Jung Park,3 Howard Lee1,4 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Clinical Trial Center, Ajou University Medical Center, Suwon ...
Kim A, Kim YK, Lee H, Park SJ
core  

The long-term effect of tacrolimus on alkali burn-induced corneal neovascularization and inflammation surpasses that of anti-vascular endothelial growth factor

, 2018
Ling Chen,* Jing Zhong,* Saiqun Li, Weihua Li, Bowen Wang, Yuqing Deng, Jin Yuan State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China *These authors contributed equally to this work ...
Li W, Li S, Wang B, Chen L, Zhong J, Yuan J, Deng Y   +6 more
core  

Tacrolimus Trough Levels.

, 2016
Tacrolimus trough levels while on antiviral treatment. The chart demonstrates the trough level of tacrolimus on the sixteen patients receiving this agent, individually, at different treatment time points.
Martha Pavlakis (3153936), Nahel Elias (3153927), Meghan E. Sise (731751), Anil Chandraker (3153945), Steve Gabardi (3153954), Eliot C. Heher (3153942), Anna E. Rutherford (3153930), Michael P. Curry (3153957), Leonardo V. Riella (613107), Raymond T. Chung (214536), Ming V. Lin (3153939), Jasmine M. Hanifi (3153951), Donald Chute (3153948), Beth M. Amundsen (3153933)   +13 more
core   +1 more source