Results 101 to 110 of about 334,748 (232)

El Diluvio Digital. Las preguntas esenciales de las humanidades en la sociedad Red.

Arte y Sociedad, 2019
Nuestra relación con el medio social está condicionada por flujos de información en los que las tecnologías digitales transforman cualquier aproximación y comprensión de los fenómenos culturales.
Jaime Repollés Llauradó
doaj  

Influence of mobility and work–family conflict on U.S. military spouse employment

Family Relations, EarlyView.
ABSTRACT Objective This study longitudinally assessed how mobility across geographic regions and work–family conflict influenced spouse employment trajectories and perceptions of career hindrance. Background The unemployment rate for U.S. military spouses has remained 21% since 2015 with specific aspects of military life, such as moving, reported as ...
Kelly A. Woodall, Claire A. Kolaja, Hope M. McMaster, Rudolph P. Rull, Andrew Furne, Nicholas J. Armstrong, Valerie A. Stander, the Millennium Cohort Family Study Team, Rani Duff, Anna Garner, Danielle Hunt, Dana Maglic, Sharmini Radakrishnan, Isabel Altarejos, Lauren Bauer, Sarah Carinio, Alex Esquivel, Travis Ray, Sabrina Richardson, Karen Tannenbaum   +19 more
wiley   +1 more source

Current perspectives on KMT2A fusion proteins and menin inhibition in paediatric acute myeloid leukaemia

The FEBS Journal, EarlyView.
Genetic rearrangements resulting in the expression of KMT2A fusion alleles can lead to dramatic transcriptional disturbances that contribute to the onset of acute leukaemias. Fortunately, menin inhibition has emerged as a promising new class of targeted therapy.
Lydia Elaine Roets, Graeme Greenfield, Katrina Mairead Lappin   +2 more
wiley   +1 more source

The Reduction of COMP Serves as a Predictor for Warning of Aortic Dissection Progression

JACC: Basic to Translational Science
Thoracic aortic dissection (TAD) is a life-threatening cardiovascular disease that is associated with high morbidity and mortality. The prevailing challenge in TAD monitoring and diagnosis is the lack of novel biomarkers.
Zhuofan Li, BS, Ze Gong, PhD, Weihao Li, MD, Yanghui Chen, PhD, Rongbo Dai, PhD, Shiyu Yang, BS, Yufei Chen, PhD, Fang Yu, MS, Yi Fu, MBBS, PhD, Wei Li, MD, Dao Wen Wang, MD, PhD, Yiting Jia, PhD, Wei Kong, MD, PhD   +12 more
doaj   +1 more source

Definition of Throw-Away Detectors (TADs) and VLF antenna for the AMPS laboratory [PDF]

A Throw Away Detector (TAD)/subsatellite to be used as an experiment platform for the test flights to map the EMI from the shuttle and during the AMPS science flights is defined.
Fennell, J. F., Koons, H. C.
core   +1 more source

Pervasive RNA-binding protein enrichment on TAD boundaries regulates TAD organization

Nucleic Acids Research
Abstract Mammalian genome is hierarchically organized by CTCF and cohesin through loop extrusion mechanism to facilitate the organization of topologically associating domains (TADs). Mounting evidence suggests additional factors/mechanisms exist to orchestrate TAD formation and maintenance.
Qiang Sun, Qin Zhou, Yulong Qiao, Xiaona Chen, Hao Sun, Huating Wang   +5 more
openaire   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Skew Premiums Around Earnings Announcements

Financial Review, EarlyView.
ABSTRACT We examine skew premiums in equity options around earnings announcements. We use the realized returns to delta‐neutral risk reversal option spreads as a proxy for the skew premiums. We find skew premiums are economically significant around earnings announcements and are not explained by changes in variance risk premiums.
Thaddeus Neururer, George Papadakis
wiley   +1 more source

Palamism Does Not Disfigure the Gospel: A Reply to Thomas Weinandy

International Journal of Systematic Theology, EarlyView.
Abstract In a 2024 article in the IJST, Fr. Thomas Weinandy argues that the theological system of Gregory Palamas is in grave error, especially with respect to its commitment to an objective ontological distinction between God's essence and His energies. In his concluding paragraph Fr.
Travis Dumsday
wiley   +1 more source