Integrated three-dimensional genomic analysis reveals that dynamic changes in chromatin structure are associated with differences in egg production performance between White Leghorn and Wenchang chickens. [PDF]
Wang S, Cao Y, Tian GG.
europepmc +1 more source
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong +8 more
wiley +1 more source
MYC in Oncogenesis and Therapeutic Implications
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang +5 more
wiley +1 more source
Recombinant TadZ from the type IVc pilus system induces protective immunity against virulent <i>Aeromonas hydrophila</i> in channel catfish (<i>Ictalurus punctatus</i>). [PDF]
Park YK +5 more
europepmc +1 more source
ABSTRACT Introduction Acute pulmonary exacerbations (APE) in persons with cystic fibrosis (PwCF) are associated with a reduction in long‐term pulmonary function. Vancomycin is recommended as first‐line treatment of methicillin‐resistant Staphylococcus aureus ‐APE in PwCF.
Jessica Barry +7 more
wiley +1 more source
Clipped Node Pathology as a Guide for Limited Axillary Surgery in Occult Breast Cancer. [PDF]
Lattimore CM +8 more
europepmc +1 more source
Ashwagandha: Is It Safe? Part 1: A Regulatory Review
ABSTRACT Over the last decade, ashwagandha ( Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler +5 more
wiley +1 more source
A comparative analysis of topological domain callers over RNA-associated interactome. [PDF]
Alaygut T, Sefer E.
europepmc +1 more source
Transfer Learning and Benchmarking for Induced Seismic Event Detection: Insights From Oklahoma
Abstract Machine learning models for microseismicity detection are often limited by the scarcity of large and high‐quality labeled data sets in many regions. To address this need, we introduce the Oklahoma Labeled AI Dataset (OKLAD), a manually curated data set compiled by the Oklahoma Geological Survey (OGS).
Hongyu Xiao +7 more
wiley +1 more source

