Results 71 to 80 of about 334,748 (232)

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

open access: yesCancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han   +5 more
wiley   +1 more source

Presidents\u27 Day in a Land at War [PDF]

open access: yes, 2013
Monday is Presidents\u27 Day, our modern conglomeration of the celebrations of Washington\u27s and Lincoln\u27s Birthdays. Of course, no one but Mary Todd, Tad and some friends were celebrating Lincoln\u27s birthday in 1863.
Rudy, John M.
core   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo   +7 more
wiley   +1 more source

The Sympathetic Ampulla

open access: yesThe Turkish Journal of Gastroenterology, 2023
James Gauci   +5 more
doaj   +1 more source

Vida y carrera política de Cornelio Tácito: una propuesta de interpretación

open access: yesPanta rei
Este artículo presenta un análisis de alguno de los más recientes descubrimientos y teorías relacionadas con la vida y la carrera del político e historiador romano, Cornelio Tácito.
Juan Luis Posadas
doaj   +1 more source

An evaluation of traits other than production and its association with the survival of dairy cows milked once a day in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of AgriScience at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2017
New Zealand dairy cows have traditionally been milked twice a day (TAD). However, an increasing number of dairy farms have shifted to once a day (OAD) milking in the last few years for several reasons. A particular emphasis has been placed on the cow’s
Martinez Rocha, Juan Felipe
core  

Emerging Perovskite Solar Cells for Building‐Integrated Photovoltaic Applications

open access: yesInformation &Functional Materials, EarlyView.
In this review, we discuss technological approaches of perovskite solar cells that are highly compatible with the requirements of building‐integrated photovoltaic applications, including semi‐transparent, colorful, and flexible perovskite solar cells.
Yongke Liang   +4 more
wiley   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho   +7 more
wiley   +1 more source

Diverse reactivity of maleimides in polymer science and beyond

open access: yesPolymer International, Volume 74, Issue 4, Page 296-306, April 2025.
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick   +2 more
wiley   +1 more source

#dametuits: Programa de formación y comunicación corporativa gamificada

open access: yesObra Digital, 2014
#dametuits fue un programa puesto en marcha en el Centro Universitario de Tecnología y Arte Digital (U-tad) que tenía como objetivo el cambio de modelo comunicacional de la institución por medio del fomento de la participación formada y optimizada de los
Carlos González Tardón   +1 more
doaj   +1 more source

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