Results 71 to 80 of about 16,904 (242)

Is phosphodiesterase type 5 inhibitor use associated with condom breakage? [PDF]

, 2009
This is an open access article - Copyright © 2009 by the BMJ Publishing Group Ltd. All rights reserved.We tested the hypothesis that phosphodiesterase type 5 inhibitor (PDE5i) use would be associated with increased likelihood of condom breakage using an
Crosby, RA, Graham, CA, Sanders, SA, Yarber, WL   +3 more
core   +1 more source

Efficacy and safety of tadalafil in a pediatric population with pulmonary arterial hypertension: phase 3 randomized, double-blind placebo-controlled study

Pulmonary Circulation, 2021
This study evaluated the efficacy and safety of tadalafil in pediatric patients with pulmonary arterial hypertension. This phase-3, international, randomized, multicenter (24 weeks double-blind placebo-controlled period; two-year, open-labeled extension ...
D. Ivy, D. Bonnet, R. Berger, G. Meyer, Simin K. Baygani, Baohui Li   +5 more
semanticscholar   +1 more source

Structure elucidation of sildenafil analogues in herbal products. [PDF]

, 2004
The structure of unknown compounds present in herbal products was elucidated using liquid chromatography-electrospray ionization-mass spectrometry, direct-infusion electrospray ionization-mass spectrometry, and nuclear magnetic resonance.
Bakker, F, Blok-Tip, L, Hamzink, M, Hartog, K D, Hove, J ten, Kaste, D de, Vredenbregt, M, Zomer, B   +7 more
core   +1 more source

Effect of low-dose tadalafil once daily on glycemic control in patients with type 2 diabetes and erectile dysfunction: a randomized, double-blind, placebo-controlled pilot study

Diabetology & Metabolic Syndrome, 2021
Background Phosphodiesterase type 5 inhibitors restore nitric oxide signaling, that plays a significant role in erectile function, and appears to counteract insulin resistance in animal and human models.
Min-Kyung Lee, Jae-Hyuk Lee, S. Sohn, Seo Yeon Lee, T. Jeong, Sae-chul Kim   +5 more
semanticscholar   +1 more source

Erectile and ejaculatory outcomes after holmium laser enucleation of the prostate: A comprehensive narrative review

UroPrecision, EarlyView.
ABSTRACT Holmium laser enucleation of the prostate (HoLEP) has emerged as a widely adopted surgical technique for the management of benign prostatic hyperplasia (BPH), regardless of prostate size; however, its impact on male sexual function—particularly in terms of erectile and ejaculatory outcomes—remains a subject of ongoing debate.
Muhammed Arif İbiş, Fabio Castiglione, Nawal Khan, Ömer Onur Çakır, Zafer Tokatlı, Önder Yaman   +5 more
wiley   +1 more source

Efficacy of tamsulosin versus tadalafil as medical expulsive therapy on stone expulsion in patients with distal ureteral stones: A randomized double-blind clinical trial

International Brazilian Journal of Urology, 2021
Purpose: To compare the effects of tadalafil, tamsulosin, and placebo as a medical expulsive therapy (MET) for distal ureteral calculi. Materials and Methods: This prospective randomized double-blind clinical trial was conducted on 132 renal colic ...
S. Falahatkar, A. Akhavan, S. Esmaeili, Atiyeh Amin, E. Kazemnezhad, A. Jafari   +5 more
semanticscholar   +1 more source

Penile rehabilitation in men after radical robotic prostatectomy: Fact or fiction?

UroPrecision, EarlyView.
Abstract Erectile dysfunction (ED) is one of the most frequent and distressing complications after radical prostatectomy (RP), significantly impairing patients’ quality of life and intimate relationships. Penile rehabilitation (PR) aims to preserve erectile tissue integrity, prevent fibrosis, and facilitate early functional recovery by restoring ...
Karen Zhang, Arnold P. P. Achermann, Hunter Hasley, Richard Bennett, Andrew Guo, Mohammed Mahdi, Lucas G. C. R. de Amorim, Helen L. Bernie, Thairo A. Pereira   +8 more
wiley   +1 more source

Evaluation of testosterone and prolactin hormones levels in erectile dysfunction patients after single oral dose of Tadalafil

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2008
Erectile dysfunction (ED) is defined as a consistent inability to sustain an erection sufficient for sexual intercourse. Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5 ...
Hayder Hamed Abed
doaj   +1 more source

Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes [PDF]

, 2015
Endothelial dysfunction (ED) plays a role in diabetic cardiovascular complications. Hyperglycemia increases cytockines involved in vascular inflammation.
Bertolini, Camilla, Fallarino, Mara, Filardi, Tiziana, Gianfrilli, Daniele, Giannetta, Elisa, Lenti, Luisa, Lenzi, Andrea, Lococo, Manuela, Mandosi, Elisabetta, Morano, Susanna, Venneri, MARY ANNA   +10 more
core   +1 more source

Tadalafil ameliorates bladder overactivity by restoring insulin-activated detrusor relaxation via the bladder mucosal IRS/PI3K/AKT/eNOS pathway in fructose-fed rats

Scientific Reports, 2021
The pathophysiologies of metabolic syndrome (MS) and overactive bladder (OAB) might overlap. Using fructose-fed rats (FFRs) as a rodent model of MS we investigated the effects of tadalafil (a phosphodiesterase type 5 inhibitor) on the dysregulated ...
Wei-Chia Lee, S. Leu, Kay L H Wu, Y. Tain, Y. Chuang, J. Chan   +5 more
semanticscholar   +1 more source