Results 51 to 60 of about 21,239 (239)

Endothelial Dysfunction in Patients With Erectile Dysfunction: A Double-Blind, Randomized-Control Trial Using Tadalafil

open access: yesSexual Medicine, 2019
Objective: To assess whether tadalafil improves endothelial dysfunction(EnD) in a placebo-controlled randomized-control trial. Methods: Erectile dysfunction and EnD were assessed by the International Index of Erectile Function (IIEF-5) and flow-mediated ...
Smita Pattanaik, DM   +4 more
doaj   +1 more source

Comparison of efficacy for erectile function and lower urinary tract symptoms of tadalafil 20 mg on-demand and 5 mg once daily in patients with erectile dysfunction [PDF]

open access: yes, 2012
Aim: To compare the improvement in erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) as well as safety of tadalafil dosed at 20 mg on-demand and 5 mg once daily among ED patients.
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core   +1 more source

Analysis of integrated clinical safety data of tadalafil in patients receiving concomitant antihypertensive medications

open access: yesThe Journal of Clinical Hypertension, 2022
This pooled safety analysis assessed the incidence of hypotension‐related treatment‐emergent adverse events (TEAEs) and major adverse cardiovascular events (MACEs) in patients with concomitant use of tadalafil and antihypertensive medications.
R. Kloner   +4 more
semanticscholar   +1 more source

Tadalafil as monotherapy and in combination regimens for the treatment of pulmonary arterial hypertension

open access: yesTherapeutic Advances in Respiratory Disease, 2013
The purpose of this review is to evaluate the use of tadalafil as monotherapy and in combination regimens for the treatment of pulmonary arterial hypertension (PAH).
Dioma U. Udeoji, Ernst R. Schwarz
doaj   +1 more source

The role of endothelin-1 in pulmonary arterial hypertension. [PDF]

open access: yes, 2014
Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
Chester, AH, Yacoub, MH
core   +1 more source

Tadalafil Treatment of Mice with Fetal Growth Restriction and Preeclampsia Improves Placental mTOR Signaling

open access: yesInternational Journal of Molecular Sciences, 2022
Fetal growth restriction (FGR) is a major cause of poor perinatal outcomes. Although several studies have been conducted to improve the prognosis of FGR in infants, no effective intrauterine treatment method has been established.
Kayo Tanaka   +7 more
semanticscholar   +1 more source

Protective effects of tadalafil against cisplatin-induced spermatogenic dysfunction.

open access: yesBiochemical and Biophysical Research Communications - BBRC, 2022
BACKGROUND Cisplatin (CDDP) is an effective anticancer drug for the treatment of malignant tumors, such as lung cancer, bladder cancer, and testicular cancer.
Y. Kaku   +6 more
semanticscholar   +1 more source

Effects of three-times-per-week versus on-demand tadalafil treatment on erectile function and continence recovery following bilateral nerve sparing radical prostatectomy: Results of a prospective, randomized, and single-center study [PDF]

open access: yes, 2015
Erectile dysfunction (ED) and urinary incontinence after bilateral nerve-sparing radical prostatectomy (BNSRP) still remain major causes of morbidity. Phosphodiesterase type 5 inhibitors (PDE5-Is) have a role in the treatment of ED after BNSRP.
Heidenreich   +31 more
core   +2 more sources

Bioequivalence and food effect of a fixed‐dose combination of macitentan and tadalafil: Adaptive design in the COVID‐19 pandemic

open access: yesPharmacology Research & Perspectives, 2021
The COVID‐19 pandemic has forced clinical studies to accommodate imposed limitations. In this study, the bioequivalence part could not be conducted as planned.
Dénes Csonka   +6 more
doaj   +1 more source

A new original nutraceutical formulation ameliorates the effect of Tadalafil on clinical score and cGMP accumulation.

open access: yesArchivio Italiano di Urologia e Andrologia, 2021
OBJECTIVE To assess the efficacy of the combination of Tadalafil 5 mg and nutritional supplements composed by Panax ginseng, Moringa Oleifera and Rutin on erectile function in men with mild and moderate vasculogenic ED.
V. Mirone   +11 more
semanticscholar   +1 more source

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