Results 1 to 10 of about 6,872 (221)

Effect of Chemical Refining on the Reduction of β-Carboline Content in Sesame Seed Oil [PDF]

open access: yesMolecules, 2023
β-carbolines (harman and norharman) are potentially mutagenic and have been reported in some vegetable oils. Sesame seed oil is obtained from roasted sesame seeds. During sesame oil processing, roasting is the key procedure to aroma enhancement, in which
Lili Shi, Ziyu Cui, Wei Liu
doaj   +2 more sources

Anti-inflammatory effects of Banisteriopsis caapi and beta-carbolines in neuronal cells: potential implications for neuro-COVID [PDF]

open access: yesFrontiers in Pharmacology
BackgroundNeuroinflammation plays a central role in neurodegenerative diseases such as Alzheimer’s and Parkinson’s, along with depression, anxiety, and infectious diseases including COVID-19.
Laura Seixas Bianco   +12 more
doaj   +2 more sources

Photocatalytic Enantioselective Radical Cascade Multicomponent Minisci Reaction of β‐Carbolines Using Diazo Compounds as Radical Precursors [PDF]

open access: yesAdvanced Science
Here, a photocatalytic asymmetric multicomponent cascade Minisci reaction of β‐carbolines with enamides and diazo compounds is reported, enabling an effective enantioselective radical C─H functionalization of β‐carbolines with high yields and ...
Yi‐Jie Gu   +4 more
doaj   +2 more sources

Stereodivergent assembly of tetrahydro-γ-carbolines via synergistic catalytic asymmetric cascade reaction

open access: yesNature Communications, 2019
Tetrahydro-γ-carbolines are the basic structural unit in many natural products and pharmaceuticals. Here, the authors report a synergistic Cu/Ir system to assemble chiral tetrahydro-γ-carbolines via a stereodivergent allylation followed by a ...
Liang Wei, Chong Shen, Chun-Jiang Wang
exaly   +2 more sources

Bioactive β-Carbolines Harman and Norharman in Sesame Seed Oils in China

open access: yesMolecules, 2022
The β-carbolines in our diet, mainly including harman and norharman, are a group of biologically active, naturally occurring plant-derived alkaloids. Fragrant sesame seed oil is one of the most popular flavor edible oils in China. Considering that sesame
Wei Liu, Zhaoyu Yang, Lili Shi, Yun Li
doaj   +1 more source

Application of High-Performance Liquid Chromatography with Fluorescence Detection for Non-Polar Heterocyclic Aromatic Amines and Acridine Derivatives Determination in Pork Loin Roasted in a Roasting Bag

open access: yesFoods, 2022
Heat treatment of meat can lead to the formation of carcinogenic organic compounds. The influence of dried fruits on the formation of non-polar heterocyclic aromatic amines (carbolines) and nitrogen derivatives of polycyclic aromatic hydrocarbons ...
Ewa Śnieżek   +4 more
doaj   +1 more source

Degradation of β-Carbolines Harman and Norharman in Edible Oils during Heating

open access: yesMolecules, 2021
The β-carbolines, mainly including harman and norharman, are a group of naturally occurring, plant-derived alkaloids, and are also considered as nonpolar heterocyclic aromatic amines.
Wei Liu   +4 more
doaj   +1 more source

Synthesis of 1-indolyl-3,5,8-substituted γ-carbolines: one-pot solvent-free protocol and biological evaluation

open access: yesBeilstein Journal of Organic Chemistry, 2021
1,5-Disubstituted indole-2-carboxaldehyde derivatives 1a–h and glycine alkyl esters 2a–c are shown to undergo a novel cascade imination-heterocylization in the presence of the organic base DIPEA to provide 1-indolyl-3,5,8-substituted γ-carbolines 3aa–ea ...
Premansh Dudhe   +6 more
doaj   +1 more source

Development in the Synthesis and Biological Activities of THβ-carboline and Its Analogs: Review

open access: yesEthiopian Journal of Science and Sustainable Development, 2022
1,2,3,4-Tetrahydro-β-carbolines (THβCs) are a large group of natural and synthetic indole alkaloids that possess a common tricyclic pyrido[3,4-b] indole scaffold that are widely distributed in nature.
Ayana Melaku Yadessa, Nigatu Bejigo
doaj   +1 more source

3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents

open access: yesPharmaceuticals, 2022
Herein, the synthesis and anticancer activity evaluation of a series of novel β-carbolines is reported. The reactivity of nitrosoalkenes towards indole was explored for the synthesis of novel tryptophan analogs where the carboxylic acid was replaced by a
João L. P. Ribeiro   +4 more
doaj   +1 more source

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