Results 1 to 10 of about 504 (130)
Degradation of β-Carbolines Harman and Norharman in Edible Oils during Heating [PDF]
Wei Liu
exaly +2 more sources
The structure of β-carboline, also called norharman (systematic name: 9H-pyrido[3,4-b]indole), C(11)H(8)N(2), has been determined at 110 K. Norharman is prevalent in the environment and the human body and is of wide biological interest. The structure exhibits intermolecular N-H···N hydrogen bonding, which results in a one-dimensional herringbone motif.
Robert J, Thatcher +1 more
openaire +2 more sources
Trait Anxiety, Coping with Stress, and Norharman
Plasma levels of the β-carboline norharman, concentration of platelet 5-HT, trait measures of anxiety, and measures of coping and defense mechanisms were compared for 15 patients with panic disorder and 24 healthy volunteers. Patients indicated that they made less use of the defense mechanism of principalization than control subjects.
Verheij, René +4 more
openaire +4 more sources
Interactions of norharman and harman with DNA
The interactions of norharman (9H-pyrido [3,4-b] indole) and harman (1-methyl-9H-pyrido [3,4-b] indole) with DNA were studied. DNA caused remarkable fluorescence quenching and change in the absorption spectra of the dyes. Scatchard plots obtained by optical titration gave Kd values of 2.2 X 10(-5)M and 7.7 X 10(-6)M, and apparent numbers of binding ...
K, Hayashi, M, Nagao, T, Sugimura
openaire +3 more sources
Norharman and Harman in Human Urine.
It has been shown that norharman and harman, present in our environment, may act as genotoxic compounds in human body. In order to have an insight of the extents of exposure to these β-carbolines, we measured their levels in human urine. Samples of 24-hr urine were collected from ten healthy volunteers eating a normal diet and three patients receiving ...
USHIYAMA, Hirofumi +5 more
openaire +2 more sources
Occurence and partition of the β-carboline norharman in rat organs [PDF]
The beta-carboline norharman was determined in plasma, brain, liver, kidney, spleen, heart and lung of the rat using HPLC with fluorescence detection. In order to improve the speed and sensitivity of this assay an earlier published sample clean-up extraction procedure and HPLC method were adjusted. Norharman was found to be present in plasma as well as
D, Fekkes, W T, Bode
openaire +2 more sources
Antimicrobial and autophototoxic effects of norharmane in termites
The fluorescent alkaloid norharmane has been isolated from Reticulitermes termites and characterized by microcoil 1H NMR, UV/Vis, mass spectrometry and GC/MS. This is the first report of norharmane in insects, which is the major component in termite fluorescence under ultraviolet light.
Siderhurst, Matthew Samuel, author +4 more
openaire +2 more sources
The role of beta-carbolines (harman/norharman) in heroin addicts
SummaryEndogenous substances resulting from interactions between alcohol and possibly opioid metabolites and neurotransmitters (dopamine, indolamines) could be mediators of the pathochemical process towards dependence. Beta-carbolines (harman/norharman) are increased in alcoholics and — according to the presented results — in heroin addicts ...
Stohler R, Rommelspacher H, Ladewig D
openaire +3 more sources
Norharman, a normal body constituent [PDF]
D, Fekkes +5 more
openaire +2 more sources
CLXXXV.—Harmine and harmaline. Part V. The synthesis of norharman
n ...
Kermack, William Ogilvy +2 more
openaire +2 more sources

