Heterocyclic Aromatic Amines and Risk of Kidney Stones: A Cross-Sectional Study in US Adults [PDF]
BackgroundHeterocyclic aromatic amines (HAAs) are a group of harmful substances produced while cooking meat at high temperatures. This study aimed to investigate the relationship between HAAs and the occurrence of kidney stones.MethodsData on the level ...
Guangyuan Zhang +3 more
doaj +2 more sources
Acylated anthocyanin inhibited the formation of heterocyclic amines in hybrid chemical model system and its underlying mechanism [PDF]
Enzymatic acylation was employed to synthesize acylated anthocyanin, and a hybrid chemical model system was used for the formation of heterocyclic amines.
Hui Teng +7 more
doaj +2 more sources
Comparison of microwave and hot-air roasting on microstructure of sesame seed, aroma-active, hazardous components, and sensory perception of sesame oil [PDF]
The unclear effects of microwaves, as a greener alternative to hot air, on sensory perception, aroma, and hazardous components of sesame oil were investigated.
Wen-ting Yin +6 more
doaj +2 more sources
Investigating of harmane, harmine, and norharman as inhibitors of MDR1 and MRP1 to overcome chemotherapy resistance in cancer cells [PDF]
Multidrug resistance efflux pumps are among the primary contributors to chemotherapy failure. Therefore, the identification of novel inhibitors with greater specificity and efficacy remains a critical objective.
Neda Abdi +5 more
doaj +2 more sources
Application of fused-grid-based CYP-Template systems for genotoxic substances to understand the metabolisms [PDF]
Understanding of metabolic processes is a key factor to evaluate biological effects of carcinogen and mutagens. Applicability of fused-grid Template* systems of CYP enzymes (Drug Metab Pharmacokinet 2019, 2020, 2021, and 2022) was tested for three ...
Yasushi Yamazoe +3 more
doaj +2 more sources
Monoamine Oxidase Inhibition by Plant-Derived β-Carbolines; Implications for the Psychopharmacology of Tobacco and Ayahuasca [PDF]
The monoamine oxidases (MAOs) are flavin-containing amine oxidoreductases responsible for metabolism of many biogenic amine molecules in the brain and peripheral tissues.
Ilana Berlowitz +3 more
doaj +5 more sources
Interactions of norharman and harman with DNA
The interactions of norharman (9H-pyrido [3,4-b] indole) and harman (1-methyl-9H-pyrido [3,4-b] indole) with DNA were studied. DNA caused remarkable fluorescence quenching and change in the absorption spectra of the dyes. Scatchard plots obtained by optical titration gave Kd values of 2.2 X 10(-5)M and 7.7 X 10(-6)M, and apparent numbers of binding ...
K, Hayashi, M, Nagao, T, Sugimura
exaly +4 more sources
Effects of Oil and Processing Conditions on Formation of Heterocyclic Amines and Polycyclic Aromatic Hydrocarbons in Pork Fiber [PDF]
Toxic compounds such as heterocyclic amines (HAs) and polycyclic aromatic hydrocarbons (PAHs) can be produced during food processing, especially meat products.
Yu-Wen Lai +2 more
doaj +2 more sources
Secondary metabolites of Minutisphaera thailandensis and Hongkongmyces kokensis revealed by LC–QTOF–MS and their antimicrobial and cytotoxic activities [PDF]
The mycelial extracts of two novel fungal species, Minutisphaera thailandensis and Hongkongmyces kokensis, were investigated for their antimicrobial, cytotoxic, and secondary metabolite profiles to assess their potential as sources of bioactive natural ...
Sarunpron Khruengsai +3 more
doaj +2 more sources
Analysis of Polycyclic Aromatic Hydrocarbons via GC-MS/MS and Heterocyclic Amines via UPLC-MS/MS in Crispy Pork Spareribs for Studying Their Formation during Frying [PDF]
This study aims to explore the effects of frying conditions on the formation of HAs and PAHs in crispy pork spareribs, a popular meat commodity sold on Taiwan’s market.
Yu-Wen Lai +2 more
doaj +2 more sources

