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Heterocyclic Aromatic Amines and Risk of Kidney Stones: A Cross-Sectional Study in US Adults [PDF]

open access: yesFrontiers in Public Health, 2022
BackgroundHeterocyclic aromatic amines (HAAs) are a group of harmful substances produced while cooking meat at high temperatures. This study aimed to investigate the relationship between HAAs and the occurrence of kidney stones.MethodsData on the level ...
Guangyuan Zhang   +3 more
doaj   +2 more sources

Acylated anthocyanin inhibited the formation of heterocyclic amines in hybrid chemical model system and its underlying mechanism [PDF]

open access: yesFood Chemistry: X, 2023
Enzymatic acylation was employed to synthesize acylated anthocyanin, and a hybrid chemical model system was used for the formation of heterocyclic amines.
Hui Teng   +7 more
doaj   +2 more sources

Comparison of microwave and hot-air roasting on microstructure of sesame seed, aroma-active, hazardous components, and sensory perception of sesame oil [PDF]

open access: yesFood Chemistry: X, 2023
The unclear effects of microwaves, as a greener alternative to hot air, on sensory perception, aroma, and hazardous components of sesame oil were investigated.
Wen-ting Yin   +6 more
doaj   +2 more sources

Investigating of harmane, harmine, and norharman as inhibitors of MDR1 and MRP1 to overcome chemotherapy resistance in cancer cells [PDF]

open access: yesScientific Reports
Multidrug resistance efflux pumps are among the primary contributors to chemotherapy failure. Therefore, the identification of novel inhibitors with greater specificity and efficacy remains a critical objective.
Neda Abdi   +5 more
doaj   +2 more sources

Application of fused-grid-based CYP-Template systems for genotoxic substances to understand the metabolisms [PDF]

open access: yesGenes and Environment, 2023
Understanding of metabolic processes is a key factor to evaluate biological effects of carcinogen and mutagens. Applicability of fused-grid Template* systems of CYP enzymes (Drug Metab Pharmacokinet 2019, 2020, 2021, and 2022) was tested for three ...
Yasushi Yamazoe   +3 more
doaj   +2 more sources

Monoamine Oxidase Inhibition by Plant-Derived β-Carbolines; Implications for the Psychopharmacology of Tobacco and Ayahuasca [PDF]

open access: yesFrontiers in Pharmacology, 2022
The monoamine oxidases (MAOs) are flavin-containing amine oxidoreductases responsible for metabolism of many biogenic amine molecules in the brain and peripheral tissues.
Ilana Berlowitz   +3 more
doaj   +5 more sources

Interactions of norharman and harman with DNA

open access: yesNucleic Acids Research, 1977
The interactions of norharman (9H-pyrido [3,4-b] indole) and harman (1-methyl-9H-pyrido [3,4-b] indole) with DNA were studied. DNA caused remarkable fluorescence quenching and change in the absorption spectra of the dyes. Scatchard plots obtained by optical titration gave Kd values of 2.2 X 10(-5)M and 7.7 X 10(-6)M, and apparent numbers of binding ...
K, Hayashi, M, Nagao, T, Sugimura
exaly   +4 more sources

Effects of Oil and Processing Conditions on Formation of Heterocyclic Amines and Polycyclic Aromatic Hydrocarbons in Pork Fiber [PDF]

open access: yesFoods, 2023
Toxic compounds such as heterocyclic amines (HAs) and polycyclic aromatic hydrocarbons (PAHs) can be produced during food processing, especially meat products.
Yu-Wen Lai   +2 more
doaj   +2 more sources

Secondary metabolites of Minutisphaera thailandensis and Hongkongmyces kokensis revealed by LC–QTOF–MS and their antimicrobial and cytotoxic activities [PDF]

open access: yesScientific Reports
The mycelial extracts of two novel fungal species, Minutisphaera thailandensis and Hongkongmyces kokensis, were investigated for their antimicrobial, cytotoxic, and secondary metabolite profiles to assess their potential as sources of bioactive natural ...
Sarunpron Khruengsai   +3 more
doaj   +2 more sources

Analysis of Polycyclic Aromatic Hydrocarbons via GC-MS/MS and Heterocyclic Amines via UPLC-MS/MS in Crispy Pork Spareribs for Studying Their Formation during Frying [PDF]

open access: yesFoods
This study aims to explore the effects of frying conditions on the formation of HAs and PAHs in crispy pork spareribs, a popular meat commodity sold on Taiwan’s market.
Yu-Wen Lai   +2 more
doaj   +2 more sources

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