Degradation of β-Carbolines Harman and Norharman in Edible Oils During Heating
Molecules, 2021 The β-carbolines, mainly including harman and norharman, are a group of naturally occurring, plant-derived alkaloids, and are also considered as nonpolar heterocyclic aromatic amines.
Wei Liu, Lili Shi
exaly +4 more sources
Tryptophan metabolite norharman secreted by cultivated Lactobacillus attenuates acute pancreatitis as an antagonist of histone deacetylases [PDF]
BMC Medicine, 2023 Background Patients with acute pancreatitis (AP) exhibit specific phenotypes of gut microbiota associated with severity. Gut microbiota and host interact primarily through metabolites; regrettably, little is known about their roles in AP biological ...
Qi Zhou +8 more
doaj +2 more sources
Effect of Chemical Refining on the Reduction of β-Carboline Content in Sesame Seed Oil [PDF]
Molecules, 2023 β-carbolines (harman and norharman) are potentially mutagenic and have been reported in some vegetable oils. Sesame seed oil is obtained from roasted sesame seeds. During sesame oil processing, roasting is the key procedure to aroma enhancement, in which
Lili Shi, Ziyu Cui, Wei Liu
doaj +2 more sources
Comprehensive Analyses of Advanced Glycation end Products and Heterocyclic Amines in Peanuts during the Roasting Process [PDF]
Molecules, 2023 Advanced glycation end products (AGEs) and heterocyclic amines (HAs) are two kinds of important harmful products formed simultaneously during the thermal processing of proteinaceous food.
Jingjing Yu +3 more
doaj +2 more sources
β-Carboline Alkaloids in Soy Sauce and Inhibition of Monoamine Oxidase (MAO) [PDF]
Molecules, 2023 Monoamine oxidase (MAO) oxidizes neurotransmitters and xenobiotic amines, including vasopressor and neurotoxic amines such as the MPTP neurotoxin. Its inhibitors are useful as antidepressants and neuroprotectants.
Tomás Herraiz
doaj +2 more sources
Effect of quercetin and oil water separation system on formation of β-carboline heterocyclic amines during frying process of braised chicken drumsticks [PDF]
Current Research in Food Science, 2023 The effect of quercetin and oil water separation system on the formation of heterocyclic amines (HAs) was investigated during the frying process of braised chicken drumsticks.
Xuefei Li +5 more
doaj +2 more sources
Evaluation of the Formation of Six Beta-Carboline Alkaloids, a Class of Natural Toxins, in Meat Products Using Liquid Chromatography Tandem Mass Spectrometry [PDF]
ToxinsBeta-carboline alkaloids (βC-alkaloids) are natural toxins found in various foods, and can also form during the thermal processing of protein-rich ingredients.
Kyung-Jik Lim +2 more
doaj +2 more sources
Variation in microbiome and metabolites is associated with advantageous effects of cholestyramine on primary biliary cholangitis with pruritus [PDF]
Microbiology SpectrumEmerging evidence implicates bile acid-intestinal microbiota interactions in the pathogenesis of pruritus associated with primary biliary cholangitis (PBC). Cholestyramine, a bile acid sequestrant, is clinically recommended for pruritus alleviation. This
Yijun Zhou +7 more
doaj +2 more sources
Polymerization-Dependent Thermal Stability of Chinese Quince Proanthocyanidins and Their Inhibition of Heterocyclic Amines in a Simulated Frying System [PDF]
FoodsHeterocyclic amines (HCAs), a class of potent mutagenic and carcinogenic compounds generated during the high-temperature processing of protein-rich foods, pose significant health risks to humans.
Can Fang +9 more
doaj +2 more sources
Investigating of harmane, harmine, and norharman as inhibitors of MDR1 and MRP1 to overcome chemotherapy resistance in cancer cells [PDF]
Scientific ReportsMultidrug resistance efflux pumps are among the primary contributors to chemotherapy failure. Therefore, the identification of novel inhibitors with greater specificity and efficacy remains a critical objective.
Neda Abdi +5 more
doaj +2 more sources