Application of fused-grid-based CYP-Template systems for genotoxic substances to understand the metabolisms [PDF]
Genes and Environment, 2023 Understanding of metabolic processes is a key factor to evaluate biological effects of carcinogen and mutagens. Applicability of fused-grid Template* systems of CYP enzymes (Drug Metab Pharmacokinet 2019, 2020, 2021, and 2022) was tested for three ...
Yasushi Yamazoe +3 more
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Effects of Oil and Processing Conditions on Formation of Heterocyclic Amines and Polycyclic Aromatic Hydrocarbons in Pork Fiber [PDF]
Foods, 2023 Toxic compounds such as heterocyclic amines (HAs) and polycyclic aromatic hydrocarbons (PAHs) can be produced during food processing, especially meat products.
Yu-Wen Lai +2 more
doaj +2 more sources
Secondary metabolites of Minutisphaera thailandensis and Hongkongmyces kokensis revealed by LC–QTOF–MS and their antimicrobial and cytotoxic activities [PDF]
Scientific ReportsThe mycelial extracts of two novel fungal species, Minutisphaera thailandensis and Hongkongmyces kokensis, were investigated for their antimicrobial, cytotoxic, and secondary metabolite profiles to assess their potential as sources of bioactive natural ...
Sarunpron Khruengsai +3 more
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Analysis of Polycyclic Aromatic Hydrocarbons via GC-MS/MS and Heterocyclic Amines via UPLC-MS/MS in Crispy Pork Spareribs for Studying Their Formation during Frying [PDF]
FoodsThis study aims to explore the effects of frying conditions on the formation of HAs and PAHs in crispy pork spareribs, a popular meat commodity sold on Taiwan’s market.
Yu-Wen Lai +2 more
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The role of beta-carbolines (harman/norharman) in heroin addicts
European Psychiatry, 1995 SummaryEndogenous substances resulting from interactions between alcohol and possibly opioid metabolites and neurotransmitters (dopamine, indolamines) could be mediators of the pathochemical process towards dependence. Beta-carbolines (harman/norharman) are increased in alcoholics and — according to the presented results — in heroin addicts ...
Stohler R, Rommelspacher H, Ladewig D
openaire +4 more sources
Development of a Novel, Simultaneous Determination Method for Heterocyclic Amines and Mycotoxins in Fried Food by UPLC-MS/MS Combined With QuEChERS. [PDF]
Food Sci Nutr• A novel QuEChERS‐UPLC‐MS/MS method was successfully developed for the simultaneous determination of two β‐carboline heterocyclic amines and seven mycotoxins in fried foods. ABSTRACT Dietary exposure to both processing contaminants and natural toxins in fried foods poses a potential health risk, but analytical methods for their simultaneous monitoring
Yang D +6 more
europepmc +2 more sources
Effects of turmeric on reducing heterocyclic aromatic amines in Chinese tradition braised meat products and the underlying mechanism. [PDF]
Food Sci Nutr, 2021 Abstract Braised meat products are kinds of popular traditional meat food in China. However, current data on the formation of Amino‐carboline congeners Heterocyclic aromatic amines (HAAs) and the inhibitory methods in braised meat products are limited. In the present study, the inhibition effect of turmeric and curcumin on the formation of β‐carboline ...
Wang Q, Li J, Li K, Li C.
europepmc +2 more sources
Research Progress on the Inhibitory Mechanism of Plant Polyphenols on the Formation of Heterocyclic Amines in Thermally Processed Meat Products [PDF]
Shipin Kexue, 2023 Heterocyclic amines (HAs) are a class of toxic compounds with strong teratogenic and carcinogenic activities which are produced during thermal processing of meat products. Three types of HAs, including 2-amino-3-methyl-imidazo[4,5-f]-quinoline (IQ) and 2-
ZHANG Shiyu, GAO Meng, WANG Wei, REN Xiaopu, XU Qian, PENG Zengqi
doaj +1 more source
Molecules, 2021 The aim of this research was to investigate the effect of the number of freeze–thaw cycles (0, 1, 3, 5, and 7) on porcine longissimus protein and lipid oxidation, as well as changes in heterocyclic aromatic amines (HAAs) and advanced glycation end ...
Xingge Wu +6 more
doaj +1 more source
Effects of Phenolic Acid Impregnation on the Formation of Advanced Glycation End Products and Heterocyclic Aromatic Amines in Roasted Peanuts [PDF]
Shipin Kexue, 2023 In order to inhibit the formation of advanced glycation end products (AGEs) and heterocyclic aromatic amines (HAAs) in roasted peanuts, six phenolic acids (caffeic acid, ferulic acid, 4-coumaric acid, vanillic acid, gallic acid and chlorogenic acid) were
YU Jingjing, YU Xiaohui, SHI Lili, LIU Wei
doaj +1 more source