Crystal structure of 4-(4b,8a-dihydro-9H-pyrido[3,4-b]indol-1-yl)-7-methyl-2H-chromen-2-one
Acta Crystallographica Section E: Crystallographic Communications, 2017 The title compound, C21H14N2O2, was prepared by Pictet–Spengler cyclization of tryptamine and 4-formyl coumarin. In the molecule, the dihedral angle between the mean planes of the coumarin and β-carboline ring systems is 63.8 (2)°.
S. Samundeeswari +2 more
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Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor [PDF]
, 2008 Essential tremor (ET) is a widespread late-life neurological disease. Genetic and environmental factors likely play an etiological role. Harmane (1-methyl-9H-pyrido[3,4-b]indole) is a potent tremor-producing neurotoxin.
Factor-Litvak, Pam +6 more
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The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes : control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway [PDF]
, 2013 Organometallic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X]+ where M = RuII or OsII and X ═ Cl or I, exhibit potent antiproliferative activity toward a range of cancer cells.
Romero-Canelón, Isolda +2 more
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Fermentation Enhanced Biotransformation of Compounds in the Kernel of Chrysophyllum albidum
Molecules, 2020 Chrysophyllum albidum Linn (African star apple) is a fruit with extensive nutritional and medicinal benefits. The fruit and kernel in the seed are both edible.
Oluwatofunmi E. Odutayo +4 more
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Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor [PDF]
, 2012 Background: Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature. This drug-induced action tremor has been proposed as a model of
Handforth, Adrian
core +4 more sources
Norharmane rhenium(
Dalton Transactions, 2015 Novel Re(i) polypyridyl complexes with norharmane as a ligand were obtained and characterized by different techniques. The nature of the electronic transitions was established by TD-DFT calculations.
Maisuls, Iván +7 more
openaire +4 more sources
Foods, 2022 The present study was conducted to explore the impact of novel water–oil mixed frying and traditional oil frying methods on the soybean oil quality and formation of trans fatty acids (TFAs) and heterocyclic amines (HCAs) in fried duck breast and skin ...
Muneer Ahmed Jamali +3 more
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Food Frontiers, Volume 1, Issue 2, Page 134-151, June 2020., 2020 Some spice/herbs are applied to inhibit heterocyclic aromatic amines (HAAs) formation Abstract Thermal processing is the most important and popular domestic cooking method. More than 30 heterocyclic aromatic amines have been identified in cooked meat using various methods. This review highlights preventive potential and mechanism of dietary polyphenols
Hui Cao +10 more
wiley +1 more source
Fermentation products of solvent tolerant marine bacterium Moraxella spp. MB1 and its biotechnological applications in salicylic acid bioconversion. [PDF]
PLoS ONE, 2013 As part of a proactive approach to environmental protection, emerging issues with potential impact on the environment is the subject of ongoing investigation. One emerging area of environmental research concerns pharmaceuticals like salicylic acid, which
Solimabi Wahidullah +2 more
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Integration of pharmacochemistry, pharmacodynamics and metabolomics to reveal active ingredients and mechanism of Nan Bao detox capsule alleviating methamphetamine addiction. [PDF]
Addict BiolExperimental flowchart: NBDC is composed of various medicinal materials such as ginseng, astragalus and polygala. UPLC‐MS is used to analyse the components of NBDC. MA addiction rats is administered with NBDC. Blood samples are subjected to metabolomic analysis.
Zhang B +5 more
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