Norharman and Harman in Human Urine.
It has been shown that norharman and harman, present in our environment, may act as genotoxic compounds in human body. In order to have an insight of the extents of exposure to these β-carbolines, we measured their levels in human urine. Samples of 24-hr urine were collected from ten healthy volunteers eating a normal diet and three patients receiving ...
Hirofumi USHIYAMA +5 more
openaire +2 more sources
Mutagenic and/or carcinogenic compounds in meat and meat products: Heterocyclic aromatic amines perspective [PDF]
Meat and meat products, which have a very important place in terms of nutrition, can endanger human health if they are not properly prepared and preserved. Meat and meat products except for products such as sushi, which are deliberately consumed raw, are
E. Oz, F. Oz, F. Oz, Е. Oz
core +2 more sources
The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development [PDF]
Chorioamnionitis is associated with adverse neurodevelopmental outcomes in preterm infants. Ureaplasma spp. are the microorganisms most frequently isolated from the amniotic fluid of women diagnosed with chorioamnionitis.
Barre, F.P.Y. +16 more
core +4 more sources
Transfer hydrogenation and antiproliferative activity of tethered half-sandwich organoruthenium catalysts [PDF]
We report the synthesis and characterization of four neutral organometallic tethered complexes, [Ru(η6-Ph(CH2)3-ethylenediamine-N-R)Cl], where R = methanesulfonyl (Ms, 1), toluenesulfonyl (Ts, 2), 4-trifluoromethylbenzenesulfonyl (Tf, 3), and 4 ...
Brabec, Viktor +10 more
core +3 more sources
Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation [PDF]
Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS).
Alain Simon +8 more
core +1 more source
Sympathoadrenergic modulation of hematopoiesis: a review of available evidence and of therapeutic perspectives [PDF]
Innervation of the bone marrow (BM) has been described more than one century ago, however the first in vivo evidence that sympathoadrenergic fibers have a role in hematopoiesis dates back to less than 25 years ago.
Afan +103 more
core +2 more sources
Addictiveness and sttractiveness of tobacco additives [PDF]
SCENIHR (Scientific Committee on Emerging and Newly Identified Health Risks): et al.The Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) has been asked to evaluate the role of tobacco additives in the addictiveness and ...
Rodríguez-Farré, Eduard +1 more
core +2 more sources
Influence of amino acids on the formation of mutagenic/carcinogenic heterocydic amines in a model system [PDF]
Mixtures of creatinine, glucose and various single amino acids were heated at 180°C for 10 min in an aqueous model system. The heated mixtures all showed mutagenic activity, ranging from 80 to 2400 TA98 revertant colonies/μmol creatinine with metabolic ...
Fay, Laurent B. +4 more
core
Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives [PDF]
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).Abstract: Marine sponges belonging to the phylum Porifera (Metazoa ...
Franco, Christopher Milton +3 more
core +2 more sources
Loss of flavonol 3‐O‐glucosyltransferase activity confers soybean resistance to leaf‐chewing insects
Significance Statement The loss of flavonol 3‐O‐glucosyltransferase activity in soybean reduces feeding damage from defoliating insects and is accompanied by a concomitant increase in proanthocyanidins (red arrowhead). Unraveling the biochemical and genetic basis of soybean resistance to leaf‐chewing insects facilitates the development of new ...
P. K. Prabhakar +8 more
wiley +1 more source

