Results 51 to 60 of about 792 (188)

Formation and Prediction of PhIP, Harman, and Norharman in Chemical Model Systems Containing Epicatechin under Various Reaction Conditions

, 2021
The aim of this study was to investigate the formation rules of 1-methyl-6-phenylimidazo­[4,5-b]-pyridine (PhIP), 1-methyl-9H-pyrido­[3,4-b]-indole (Harman), and 9H-pyrido­[3,4-b]-indole (Norharman) in chemical model systems containing epicatechin under ...
Huan Liu (281351), Ruixia Chen, Huan Liu, Teng Hui (132560), Dequan Zhang, Yanlei Li (5642705), Yanlei Li, Dequan Zhang (7494857), Ruixia Chen (11775633), Teng Hui, Xiaoyue Yang (1702618), Zhenyu Wang, Xiaoyue Yang, Zhenyu Wang (580934)   +13 more
core   +1 more source

Mass spectra of norharman (A) and harman (B).

, 2018
Mass spectra of norharman (A) and harman (B).
Anna Katarzyna Wrońska (4922722), Agata Kaczmarek (4922719), Mieczysława Irena Boguś (4922725), Michalina Kazek (4922728)   +3 more
core   +1 more source

Loss of flavonol 3‐O‐glucosyltransferase activity confers soybean resistance to leaf‐chewing insects

The Plant Journal, Volume 126, Issue 1, April 2026.
Significance Statement The loss of flavonol 3‐O‐glucosyltransferase activity in soybean reduces feeding damage from defoliating insects and is accompanied by a concomitant increase in proanthocyanidins (red arrowhead). Unraveling the biochemical and genetic basis of soybean resistance to leaf‐chewing insects facilitates the development of new ...
P. K. Prabhakar, M. A. Ortega, B.‐K. Ha, P. R. LaFayette, S. A. Harding, C. J. Tsai, B. R. Urbanowicz, H. R. Boerma, W. A. Parrott   +8 more
wiley   +1 more source

Additional file 1 of Tryptophan metabolite norharman secreted by cultivated Lactobacillus attenuates acute pancreatitis as an antagonist of histone deacetylases

, 2023
Additional file 1: Table S1. Primer sequences used for CHIP-qPCR assay. Table S2. Primer sequences used for qPCR assay. Fig. S1. The dose validation of tryptophan, LPS, and metabolites. Fig. S2.
Linlin Lv (5591369), Deshi Dong (11665594), Yu Wu (54264), Dawei Deng (1678783), Dong Shang (4990103), Qi Zhou (7408), Fangyue Guo (8597517), Xufeng Tao (5864738), Hong Xiang (16889810)   +8 more
core   +1 more source

Effect of Salt and pH Stress of Bioactive Metabolite Production in Geitlerinema carotinosum

International Journal of Secondary Metabolite, 2017
Cyanobacterial metabolites are natural products that have an important feature in pharmaceutical and medicinal industries. In this study, the presence of the secondary metabolite norharmane in the indole structure was determined in Geitlerinema ...
Tunay Karan, Ramazan Erenler
doaj   +1 more source

One‐Pot Synthesis of Novel β‐Carboline‐{α‐Acylaminoamide}‐Bisindole Derivatives: Antibacterial Evaluation, Molecular Docking, and Density Functional Theory Studies

ChemistryOpen, Volume 14, Issue 12, December 2025.
A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) employing an atom‐economical one‐pot Ugi four‐component reaction and their antibacterial testing alongside docking studies, is reported. A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) is designed and synthesized employing an atom‐economical one‐pot Ugi ...
Ankit Kumar Atri, Lavanya Khullar, Gobind Kumar, Sahil Mishra, Tamanna Dua, Vinay Singh, Kusum Harjai, Parvesh Singh, Vasundhara Singh   +8 more
wiley   +1 more source

Effect of topical application of harman and norharman on pupation of Galleria mellonella larvae.

, 2018
1H- harman 750 ppm, 2H- harman 1000 ppm, 3H- harman 1250 ppm. 1N- norharman 750 ppm, 2N- norharman 1000 ppm, 3N- norharman 1250 ppm. The day of administration of the alkaloids (final larval instar day 3) is marked with the arrow.
Anna Katarzyna Wrońska (4922722), Agata Kaczmarek (4922719), Mieczysława Irena Boguś (4922725), Michalina Kazek (4922728)   +3 more
core   +1 more source

The Mechanism Exploration of Traditional Chinese Medicine's “Different Treatments for Same Disease” Concept in Osteoporosis Therapy: A Serum Metabolomics Study

Journal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT The “different treatments for same disease” is an important concept of traditional Chinese medicine (TCM) therapy. In TCM, osteoporosis (OP) treatment is aimed at invigorating blood, strengthening spleen, and tonifying kidneys, and their typical herbs are Angelica sinensis (Oliv.) Diels (Danggui, DG), Poria cocos (Schw.) Wolf (Fuling, FL), and
Jingyuan Wen, Xuefeng Li, Zhen Wu, Liu Jiangyuan, Guanyin Wang, Xu Wang, Zhengsheng Bao, Yang Yu, Pinger Wang, Zhenyu Shi, Bing Xu, Yunhuo Cai, Hongting Jin, Jiali Chen   +13 more
wiley   +1 more source

Norharman-induced motoric impairment in mice: Neurodegeneration and glial activation in substantia nigra

, 2006
The beta-carboline norharman is present in cooked food and tobacco smoke and show structural resemblance to the neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Fredriksson, Anders,, Brittebo, Eva B,, Östergren, Anna,   +2 more
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Proteins recognized by anti-5-HTR1B and anti-5-HTR2B antibodies in Galleria mellonella haemocytes are affected by Conidiobolus coronatus infection and its fungal metabolites

The European Zoological Journal
Galleria mellonella is now a robust invertebrate model for host–pathogen interaction, neuroimmune responses, and immunomodulatory mechanisms. In this study, we investigated the expression of two proteins recognized by 5-HTR1B or 5-HTR2B antibodies, in ...
A. K. Wrońska, M. I. Boguś
doaj   +1 more source