Results 51 to 60 of about 890 (147)

MOESM2 of Harman and norharman, metabolites of the entomopathogenic fungus Conidiobolus coronatus (Entomophthorales), affect the serotonin levels and phagocytic activity of hemocytes, insect immunocompetent cells, in Galleria mellonella (Lepidoptera)

open access: yes, 2019
Additional file 2: Table S2. Phagocytic activity of G. mellonella hemocytes after application of norharman and harman—raw data. The data are expressed as the percentage of phagocytosis compared with control values (100%).
Anna Wrońska (6505937)   +1 more
core   +1 more source

Heat‐Induced Toxicants: Sensory Appeal Distracts Consumers' Attention From Potential Toxicological Risks of Thermally Processed Foods

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
The central paradox of thermal processing of foods. (A) The application of heat (e.g., frying, baking, grilling) to food initiates complex chemical reactions, most notably the Maillard reaction and thermal degradation of protein, lipids, and carbohydrate. (B) These reactions create a desirable sensory experience characterized by enticing aromas, golden‐
Joachim Dotto Matondo   +1 more
wiley   +1 more source

Loss of flavonol 3‐O‐glucosyltransferase activity confers soybean resistance to leaf‐chewing insects

open access: yesThe Plant Journal, Volume 126, Issue 1, April 2026.
Significance Statement The loss of flavonol 3‐O‐glucosyltransferase activity in soybean reduces feeding damage from defoliating insects and is accompanied by a concomitant increase in proanthocyanidins (red arrowhead). Unraveling the biochemical and genetic basis of soybean resistance to leaf‐chewing insects facilitates the development of new ...
P. K. Prabhakar   +8 more
wiley   +1 more source

Effect of topical application of harman and norharman on pupation of Galleria mellonella larvae.

open access: yes, 2018
1H- harman 750 ppm, 2H- harman 1000 ppm, 3H- harman 1250 ppm. 1N- norharman 750 ppm, 2N- norharman 1000 ppm, 3N- norharman 1250 ppm. The day of administration of the alkaloids (final larval instar day 3) is marked with the arrow.
Anna Katarzyna Wrońska (4922722)   +3 more
core   +1 more source

Effect of Salt and pH Stress of Bioactive Metabolite Production in Geitlerinema carotinosum

open access: yesInternational Journal of Secondary Metabolite, 2017
Cyanobacterial metabolites are natural products that have an important feature in pharmaceutical and medicinal industries. In this study, the presence of the secondary metabolite norharmane in the indole structure was determined in Geitlerinema ...
Tunay Karan, Ramazan Erenler
doaj   +1 more source

Occurrence and partition of the β-carboline norharman in rat organs

open access: yes, 1993
The β-carboline norharman was determined in plasma, brain, liver, kidney, spleen, heart and lung of the rat using HPLC with fluorescence detection.
Bode, W.T. (Willem), Fekkes, D. (Durk)
core   +1 more source

One‐Pot Synthesis of Novel β‐Carboline‐{α‐Acylaminoamide}‐Bisindole Derivatives: Antibacterial Evaluation, Molecular Docking, and Density Functional Theory Studies

open access: yesChemistryOpen, Volume 14, Issue 12, December 2025.
A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) employing an atom‐economical one‐pot Ugi four‐component reaction and their antibacterial testing alongside docking studies, is reported. A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) is designed and synthesized employing an atom‐economical one‐pot Ugi ...
Ankit Kumar Atri   +8 more
wiley   +1 more source

Proteins recognized by anti-5-HTR1B and anti-5-HTR2B antibodies in Galleria mellonella haemocytes are affected by Conidiobolus coronatus infection and its fungal metabolites

open access: yesThe European Zoological Journal
Galleria mellonella is now a robust invertebrate model for host–pathogen interaction, neuroimmune responses, and immunomodulatory mechanisms. In this study, we investigated the expression of two proteins recognized by 5-HTR1B or 5-HTR2B antibodies, in ...
A. K. Wrońska, M. I. Boguś
doaj   +1 more source

The Mechanism Exploration of Traditional Chinese Medicine's “Different Treatments for Same Disease” Concept in Osteoporosis Therapy: A Serum Metabolomics Study

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT The “different treatments for same disease” is an important concept of traditional Chinese medicine (TCM) therapy. In TCM, osteoporosis (OP) treatment is aimed at invigorating blood, strengthening spleen, and tonifying kidneys, and their typical herbs are Angelica sinensis (Oliv.) Diels (Danggui, DG), Poria cocos (Schw.) Wolf (Fuling, FL), and
Jingyuan Wen   +13 more
wiley   +1 more source

SBSE(EG-Silicone)-UFLC-MS/MS and HPLC-Flu Analysis of Norharman in Passiflora edulis Rinds

open access: yes, 2019
Previous studies on Passiflora edulis (sour passion fruit) rinds reported some biological activities and there is a growing interest on rinds flour as a possible functional food, but its alkaloid composition was not detailed investigated.
Vítor F. Freire (4985603)   +2 more
core   +1 more source

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