Results 71 to 80 of about 1,271 (193)

Effect of Salt and pH Stress of Bioactive Metabolite Production in Geitlerinema carotinosum

International Journal of Secondary Metabolite, 2017
Cyanobacterial metabolites are natural products that have an important feature in pharmaceutical and medicinal industries. In this study, the presence of the secondary metabolite norharmane in the indole structure was determined in Geitlerinema ...
Tunay Karan, Ramazan Erenler
doaj   +1 more source

One‐Pot Synthesis of Novel β‐Carboline‐{α‐Acylaminoamide}‐Bisindole Derivatives: Antibacterial Evaluation, Molecular Docking, and Density Functional Theory Studies

ChemistryOpen, Volume 14, Issue 12, December 2025.
A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) employing an atom‐economical one‐pot Ugi four‐component reaction and their antibacterial testing alongside docking studies, is reported. A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) is designed and synthesized employing an atom‐economical one‐pot Ugi ...
Ankit Kumar Atri, Lavanya Khullar, Gobind Kumar, Sahil Mishra, Tamanna Dua, Vinay Singh, Kusum Harjai, Parvesh Singh, Vasundhara Singh   +8 more
wiley   +1 more source

Momordica charantia (Indian and Chinese Bitter Melon) Extracts Inducing Apoptosis in Human Lung Cancer Cell Line A549 via ROS‐Mediated Mitochodria Injury

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Lung cancer is the leading cause of cancer related deaths worldwide with about 40% occurring in developing countries. The two varieties of Momordica charantia, which are Chinese and Indian bitter melon, have been subjected to antiproliferative activity in human non‐small cell lung cells A549.
Siroshini Thiagarajan, Daryl J. Arapoc, Nurul Husna Shafie, Yong Yoke Keong, Hasnah Bahari, Zainah Adam, Thandar Ei, Silvia Wein   +7 more
wiley   +1 more source

The Mechanism Exploration of Traditional Chinese Medicine's “Different Treatments for Same Disease” Concept in Osteoporosis Therapy: A Serum Metabolomics Study

Journal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT The “different treatments for same disease” is an important concept of traditional Chinese medicine (TCM) therapy. In TCM, osteoporosis (OP) treatment is aimed at invigorating blood, strengthening spleen, and tonifying kidneys, and their typical herbs are Angelica sinensis (Oliv.) Diels (Danggui, DG), Poria cocos (Schw.) Wolf (Fuling, FL), and
Jingyuan Wen, Xuefeng Li, Zhen Wu, Liu Jiangyuan, Guanyin Wang, Xu Wang, Zhengsheng Bao, Yang Yu, Pinger Wang, Zhenyu Shi, Bing Xu, Yunhuo Cai, Hongting Jin, Jiali Chen   +13 more
wiley   +1 more source

Proteins recognized by anti-5-HTR1B and anti-5-HTR2B antibodies in Galleria mellonella haemocytes are affected by Conidiobolus coronatus infection and its fungal metabolites

The European Zoological Journal
Galleria mellonella is now a robust invertebrate model for host–pathogen interaction, neuroimmune responses, and immunomodulatory mechanisms. In this study, we investigated the expression of two proteins recognized by 5-HTR1B or 5-HTR2B antibodies, in ...
A. K. Wrońska, M. I. Boguś
doaj   +1 more source

Stability of tryptophan during food processing and storage: 2. A comparison of methods used for the measurement of tryptophan losses in processed foods [PDF]

, 2017
1. Tryptophan losses in stored milk powders and in different model systems representing the major reactions of food proteins during processing and storage were determined using four different chemical methods and in a rat assay. 2.
Hurrell, R. F., Klein, A., Nielsen, Henrik K.   +2 more
core  

Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules [PDF]

, 2018
Understanding the molecular mechanisms regulating cardiac cell proliferation during the embryonic, fetal and adult life holds a paramount importance in view of developing innovative strategies aimed at inducing myocardial regeneration after cardiac ...
Torrini, Consuelo
core   +1 more source

Recent Perspectives on Meat Consumption and Cancer Proliferation

Journal of Food Processing and Preservation, Volume 2025, Issue 1, 2025.
Red and processed meat consumption has been associated with a higher risk of developing several types of cancer such as colorectal, prostate, breast, lung, and pancreatic cancers according to a recent investigation by multiple in vivo and in vitro studies.
Ushna Momal, Hammad Naeem, Farhan Aslam, Muhammad Shahbaz, Muhammad Imran, Muzzamal Hussain, Awais Ahmad, Anjuman Gul Memon, Ahmed Mujtaba, Muhammad Atif, Tahir Mehmood, Tadesse Fenta Yehuala, Essam Hebishy   +12 more
wiley   +1 more source

Cooking with elaborate recipes can reduce the formation of mutagenic heterocyclic amines and promote comutagenic amines [PDF]

, 2019
Heterocyclic amines (HCAs) are foodborne carcinogens which formation is highly dependent on cooking conditions. HCAs have been commonly quantified in food items prepared with simple procedures.
[IARC] International Agency for Research on Cancer, Khan MR, Lluís Puignou, Mohammad Rizwan Khan, Mu Naushad, Rosa Busquets, Sadrieh N, Sinha R   +7 more
core   +2 more sources

Mechanism of action of “cistanche deserticola–Polygala” in treating Alzheimer's disease based on network pharmacology methods and molecular docking analysis

IET Systems Biology, Volume 18, Issue 6, Page 271-284, December 2024.
Differential expression of genes between AD patients and the normal population (a) Basic information of GSE5281 dataset. AD patient samples were labelled with green, while control group samples were labelled with purple. (b) Uniform manifold approximation and projection(UMAP) of differentially expressed gene (DEG) in GSE5281. (c) Expression density map
Shaoqiang Wang, Yifan Wang
wiley   +1 more source