Results 91 to 100 of about 792 (188)

CLXXXV.—Harmine and harmaline. Part V. The synthesis of norharman

J. Chem. Soc., Trans., 1921
n ...
Kermack, William Ogilvy, Perkin, William Henry, Robinson, Robert   +2 more
openaire   +2 more sources

Structure of DNA Adduct Formed with Aminophenylnorharman, Being Responsible for the Comutagenic Action of Norharman with Aniline

, 2016
A mutagenic heterocyclic amine (HCA), 9-(4‘-aminophenyl)-9H-pyrido[3,4-b]indole (aminophenylnorharman, APNH), is produced in the presence of S9 mix by the reaction of norharman and aniline, both of which are nonmutagenic and abundantly present in our ...
Rena Nishigaki (2667439), Keiji Wakabayashi (405453), Takeji Takamura-Enya (2337823), Yukari Totsuka (405452), Nobuo Kawahara (1647856), Takashi Sugimura (78970)   +5 more
core   +1 more source

Unveiling heterocyclic aromatic amines (HAAs) in thermally processed meat products: Formation, toxicity, and strategies for reduction - A comprehensive review. [PDF]

Food Chem X, 2023
Wang H, Chu X, Du P, He H, He F, Liu Y, Wang W, Ma Y, Wen L, Wang Y, Oz F, Abd El-Aty AM.   +11 more
europepmc   +1 more source

Identification and occurrence of β-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO)

, 2007
Monoamine oxidase (MAO) is a mitochondrial enzyme involved in the oxidative catabolism of neurotransmitters and xenobiotic amines, including vasopressor and neurotoxic amines, and a current target for antidepressant and neuroprotective drugs.
Herraiz Tomico, Tomás
core   +1 more source

Dietary fibres from Brassica vegetables bind heterocyclic amines in vitro (abstract only)

Czech Journal of Food Sciences, 2004
An association between the intake of heterocyclic amines (HAs) and development of cancer have been observed in epidemiological studies, while in other studies no such correlation has been found.
K. Skog, R. Maul, M. Nyman
doaj  

Evaluation of the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to toxic pyridinium cations by monoamine oxidase (MAO) enzymes and its use to search for new MAO inhibitors and protective agents

, 2013
Monoamine oxidase (MAO) enzymes catalyze the oxidative deamination of amines and neurotransmitters and inhibitors of MAO are useful as neuroprotectants. This work evaluates the human MAO-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Herraiz Tomico, Tomás
core   +1 more source

Effect of thermal treatments on the formation of heterocyclic aromatic amines in various meats

, 2014
Heterocyclic aromatic amines (HAAs), the potential mutagens/carcinogens, are formed during cooking meat at higher temperature. The current study was designed to evaluate the effects of various cooking methods, i.e., pan frying, deep frying, charcoal ...
Raza, A., Shabbir, M. A., Khan, M. I., Sultan, S., Suleria, H. A. R.   +4 more
core   +1 more source

Inhibitory effects of pomegranate seed extract on the formation of heterocyclic aromatic amines in beef and chicken meatballs after cooking by four different methods

, 2014
Beef and chicken meatballs with a 0.5% (w/w) pomegranate seed extract were cooked using four different cooking methods (oven roasting, pan cooking, charcoal-barbecue, and deep-fat frying) and six heterocyclic aromatic amines; IQ MeIQx, 4,8-DiMeIQx, PhIP,
Uren, Ali, Keskekoglu, Hasan
core   +1 more source

Selective Retention of β-Carbolines and 7,12-Dimethylbenz[a]anthracene in the Brain [Elektronisk resurs] : Role of Neuromelanin and Cytochrome P450 for Toxicity

, 2005
The ß-carbolines norharman and harman structurally resemble the synthetic compound 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) that is known for its ability to damage neuromelanin-containing dopaminergic neurons of the substantia nigra and ...
Lindquist, Nils Gunnar, Tjälve, Hans,, Svensson, Anne-Lie, Brittebo, Eva, Östergren, Anna,   +4 more
core  

Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells. [PDF]

Chem Res Toxicol, 2023
Bellamri M, Brandt K, Cammerrer K, Syeda T, Turesky RJ, Cannon JR.   +5 more
europepmc   +1 more source