Results 101 to 110 of about 792 (188)

Selective Retention of β-Carbolines and 7,12-Dimethylbenz[a]anthracene in the Brain : Role of Neuromelanin and Cytochrome P450 for Toxicity

, 2005
The ß-carbolines norharman and harman structurally resemble the synthetic compound 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) that is known for its ability to damage neuromelanin-containing dopaminergic neurons of the substantia nigra and ...
Östergren, Anna
core  

Comutagenic Action of Norharman and Harman

Proceedings of the Japan Academy, 1977
NAGAO, Minako, YAHAGI, Takie, KAWACHI, Takashi, SUGIMURA, Takashi, KOSUGE, Takuo, TSUJI, Kuniro, WAKABAYASHI, Keiji, MIZUSAKI, Shigenobu, MATSUMOTO, Takashi   +8 more
openaire   +2 more sources

Dual-pathway detoxification by <i>Dendrobium nobile</i> Lindl. Polysaccharide: concurrent suppression of bound heterocyclic amine release and heterocyclic amine-elicited cytotoxicity during gastrointestinal digestion. [PDF]

Food Chem X
Le Y, Zhang C, Xiao J, Lei H, Quan W, Zhu H, Xiong S, Sheng J, Sun P, Xu H, Xue C.   +10 more
europepmc   +1 more source

Commentary: Harmane potentiates nicotine reinforcement through MAO-A inhibition at the dose related to cigarette smoking. [PDF]

Front Mol Neurosci, 2023
Truman P.
europepmc   +1 more source

<i>Amomum villosum</i> Lour. Polyphenols extract: Effective inhibitors of heterocyclic aromatic amines in grilled beef patties. [PDF]

Food Chem X
Huang Y, Liu Y, Jia BZ, Xu ZL, Luo L.
europepmc   +1 more source

High affinity binding of β-carbolines to imidazoline I2B receptors and MAO-A in rat tissues: Norharman blocks the effect of morphine withdrawal on DOPA/noradrenaline synthesis in the brain

[eng] This study was designed to determine the affinity and binding profile of h-carbolines for imidazoline I2 receptors and catalytic sites of monoamine oxidase (MAO)-A/B in rat brain and liver. The aim was also directed to assess the in vivo effects of
Asensio Landa, Antonio José, García-Sevilla Jesús Andrés, Moranta Mesquida, David, Esteban Valdés, Susana Cristina, Miralles Socías, Antonio, Sastre-Coll, Antonio   +5 more
core  

Modulating Bile Acid Metabolism: The Role of Blautia coccoides in Acute Pancreatitis. [PDF]

Cell Mol Gastroenterol Hepatol
Lu G.
europepmc   +1 more source

Monoamine Oxidase Inhibitors Present in Tobacco Modulate Dopamine Balance Via the Dopamine Transporter. [PDF]

ACS Chem Neurosci
Saro G, Johne S, Latino DARS, Moine F, van der Toorn M, Mathis C, Veljkovic E.   +6 more
europepmc   +1 more source

Simultaneous determination of three β-carbolines alkaloids and Ephedrine in Pinellia Tuber by using LC/ESI(+)/MS/MS

, 2014
本研究是開發以液相層析串聯質譜術在電灑游離法正離子模式下偵測半夏與兩種炮製半夏及七種含半夏之中藥複方中生物鹼成分Ephedrine、Harman、Norharman、Harmine之定量分析之研究。在本篇研究中，成功地發展出快速具選擇性的LC/ESI/MS/MS的方法，對半夏中四個生物鹼類成分做定量分析之研究。定量結果顯示偵測極限(LODs)分別為Ephedrine：4.5 ng/g；Harman：2.5 ng/g；Norharman：1.5 ng/g；Harmine：4.2 ng/g ...
Liu, Yu-Min, 劉育閔
core  

Mitigation of heterocyclic amines, polycyclic aromatic hydrocarbons, and acrylamide in air-fried chicken and beef: effects of cooking methods and marinades. [PDF]

Food Sci Biotechnol
Kwon J, Kim I, Lee KW, Jung M, Lee H, Kim S, Moon B, Lee J.   +7 more
europepmc   +1 more source