Bioactive β-Carbolines Harman and Norharman in Sesame Seed Oils in China [PDF]
Molecules, 2022 The β-carbolines in our diet, mainly including harman and norharman, are a group of biologically active, naturally occurring plant-derived alkaloids. Fragrant sesame seed oil is one of the most popular flavor edible oils in China. Considering that sesame
Wei Liu, Zhaoyu Yang, Lili Shi, Yun Li
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Monoamine Oxidase Inhibition by Plant-Derived β-Carbolines; Implications for the Psychopharmacology of Tobacco and Ayahuasca [PDF]
Frontiers in Pharmacology, 2022 The monoamine oxidases (MAOs) are flavin-containing amine oxidoreductases responsible for metabolism of many biogenic amine molecules in the brain and peripheral tissues.
Ilana Berlowitz +3 more
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Degradation of β-Carbolines Harman and Norharman in Edible Oils during Heating [PDF]
Molecules, 2021 The β-carbolines, mainly including harman and norharman, are a group of naturally occurring, plant-derived alkaloids, and are also considered as nonpolar heterocyclic aromatic amines.
Wei Liu +4 more
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3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents [PDF]
Pharmaceuticals, 2022 Herein, the synthesis and anticancer activity evaluation of a series of novel β-carbolines is reported. The reactivity of nitrosoalkenes towards indole was explored for the synthesis of novel tryptophan analogs where the carboxylic acid was replaced by a
João L. P. Ribeiro +4 more
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The Simultaneous Formation of Acrylamide, β-carbolines, and Advanced Glycation End Products in a Chemical Model System: Effect of Multiple Precursor Amino Acids [PDF]
Frontiers in Nutrition, 2022 This study investigated the effect of multiple precursor amino acids on the simultaneous formation of acrylamide, β-carbolines (i. e., harmane and norharmane), and advanced glycation end products (AGEs) [i.e., Nε-(carboxymethyl)lysine and Nε ...
Cuyu Chen +8 more
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Photocatalytic Enantioselective Radical Cascade Multicomponent Minisci Reaction of β‐Carbolines Using Diazo Compounds as Radical Precursors [PDF]
Advanced ScienceHere, a photocatalytic asymmetric multicomponent cascade Minisci reaction of β‐carbolines with enamides and diazo compounds is reported, enabling an effective enantioselective radical C─H functionalization of β‐carbolines with high yields and ...
Yi‐Jie Gu +4 more
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A Structure–Activity Relationship Study of Trypargine and Opacaline β-Carbolines [PDF]
Marine DrugsThe marine environment represents a rich source of novel antimicrobial compounds. This study investigated the isolation and synthesis of antimicrobial agents from the New Zealand ascidian Pseudodistoma opacum to identify natural products and derivatives ...
Dan Chen +4 more
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A β-carboline natural product induces oxidative stress in Fusarium graminearum and limits the virulence of multiple fungal phytopathogens [PDF]
mBioThe emergence of fungicide-resistant pathogens of many agronomically important crop species necessitates the development of novel strategies for controlling diseases caused by fungi.
Bradley Laflamme +13 more
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Design and Synthesis of Fluorescent 1,3-Diaryl-β-carbolines and 1,3-Diaryl-3,4-dihydro-β-carbolines [PDF]
ACS Omega, 2021 JiYang Pu +5 more
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Synthesis and biological evaluation of novel N9-heterobivalent β-carbolines as angiogenesis inhibitors [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 A series of novel N9-heterobivalent β-carbolines has been synthesized. All the novel compounds were tested for their anticancer activity against six tumour cell lines in vitro.
Liang Guo +5 more
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