3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents [PDF]
Pharmaceuticals, 2022 Herein, the synthesis and anticancer activity evaluation of a series of novel β-carbolines is reported. The reactivity of nitrosoalkenes towards indole was explored for the synthesis of novel tryptophan analogs where the carboxylic acid was replaced by a
João L. P. Ribeiro +4 more
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Bioactive β-Carbolines Harman and Norharman in Sesame Seed Oils in China [PDF]
Molecules, 2022 The β-carbolines in our diet, mainly including harman and norharman, are a group of biologically active, naturally occurring plant-derived alkaloids. Fragrant sesame seed oil is one of the most popular flavor edible oils in China. Considering that sesame
Wei Liu, Zhaoyu Yang, Lili Shi, Yun Li
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Degradation of β-Carbolines Harman and Norharman in Edible Oils during Heating [PDF]
Molecules, 2021 The β-carbolines, mainly including harman and norharman, are a group of naturally occurring, plant-derived alkaloids, and are also considered as nonpolar heterocyclic aromatic amines.
Wei Liu +4 more
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Monoamine Oxidase Inhibition by Plant-Derived β-Carbolines; Implications for the Psychopharmacology of Tobacco and Ayahuasca [PDF]
Frontiers in Pharmacology, 2022 The monoamine oxidases (MAOs) are flavin-containing amine oxidoreductases responsible for metabolism of many biogenic amine molecules in the brain and peripheral tissues.
Ilana Berlowitz +3 more
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The Simultaneous Formation of Acrylamide, β-carbolines, and Advanced Glycation End Products in a Chemical Model System: Effect of Multiple Precursor Amino Acids [PDF]
Frontiers in Nutrition, 2022 This study investigated the effect of multiple precursor amino acids on the simultaneous formation of acrylamide, β-carbolines (i. e., harmane and norharmane), and advanced glycation end products (AGEs) [i.e., Nε-(carboxymethyl)lysine and Nε ...
Cuyu Chen +8 more
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Photocatalytic Enantioselective Radical Cascade Multicomponent Minisci Reaction of β‐Carbolines Using Diazo Compounds as Radical Precursors [PDF]
Advanced ScienceHere, a photocatalytic asymmetric multicomponent cascade Minisci reaction of β‐carbolines with enamides and diazo compounds is reported, enabling an effective enantioselective radical C─H functionalization of β‐carbolines with high yields and ...
Yi‐Jie Gu +4 more
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Design and Synthesis of Fluorescent 1,3-Diaryl-β-carbolines and 1,3-Diaryl-3,4-dihydro-β-carbolines [PDF]
ACS Omega, 2021 JiYang Pu +5 more
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Synthesis and biological evaluation of novel N9-heterobivalent β-carbolines as angiogenesis inhibitors [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 A series of novel N9-heterobivalent β-carbolines has been synthesized. All the novel compounds were tested for their anticancer activity against six tumour cell lines in vitro.
Liang Guo +5 more
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An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin Y [PDF]
Beilstein Journal of Organic Chemistry, 2014 A novel synthetic methodology has been developed for the synthesis of dihydro-β-carboline derivatives employing oxidative amidation–Bischler–Napieralski reaction conditions using tryptamine and 2,2-dibromo-1-phenylethanone as key starting materials.
Suresh Babu Meruva +4 more
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Anti-inflammatory effects of Banisteriopsis caapi and beta-carbolines in neuronal cells: potential implications for neuro-COVID [PDF]
Frontiers in PharmacologyBackgroundNeuroinflammation plays a central role in neurodegenerative diseases such as Alzheimer’s and Parkinson’s, along with depression, anxiety, and infectious diseases including COVID-19.
Laura Seixas Bianco +12 more
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