Comprehensive review of β-carbolines from microbes and their biosynthesis
European Journal of Medicinal Chemistry Reportsβ-carbolines were historically known as plant-derived metabolites. They are known to exhibit a broad spectrum of biological activities with clinical and economic significance.
Mary Ayeko Twumasi +4 more
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An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin Y [PDF]
Beilstein Journal of Organic Chemistry, 2014 A novel synthetic methodology has been developed for the synthesis of dihydro-β-carboline derivatives employing oxidative amidation–Bischler–Napieralski reaction conditions using tryptamine and 2,2-dibromo-1-phenylethanone as key starting materials.
Suresh Babu Meruva +4 more
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Anti-inflammatory effects of Banisteriopsis caapi and beta-carbolines in neuronal cells: potential implications for neuro-COVID [PDF]
Frontiers in PharmacologyBackgroundNeuroinflammation plays a central role in neurodegenerative diseases such as Alzheimer’s and Parkinson’s, along with depression, anxiety, and infectious diseases including COVID-19.
Laura Seixas Bianco +12 more
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Tricyclic Imidazolidin-4-ones by Witkop Oxidation of Tetrahydro-β-carbolines. [PDF]
J Org Chem, 2020 1-Substituted and 1,1-disubstituted tetrahydro-β-carbolines undergo sodium periodate oxidative ring expansion in the presence of formaldehyde and other aldehydes to form 5,6-dihydro-7H-1,4-methanobenzo[e][1,4]diazonine-2,7(3H)-diones in 30–81% yield.
Leas DA +6 more
europepmc +3 more sources
β-Carbolines in Experiments on Laboratory Animals [PDF]
International Journal of Molecular Sciences, 2020 Agnieszka Fedoruk-Wyszomirska +2 more
exaly +2 more sources
Bioactive β-Carbolines in Food: A Review [PDF]
Nutrients, 2019 Paulina Piechowska +2 more
exaly +2 more sources
Design, Synthesis, Antiproliferative Evaluation, and Molecular Docking Studies of N‑(3-Hydroxyindole)-Appended β‑Carbolines/Tetrahydro-β-Carbolines Targeting Triple-Negative and Non-Triple-Negative Breast Cancer [PDF]
ACS Omega, 2020 Bharvi Sharma +7 more
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Effect of Chemical Refining on the Reduction of β-Carboline Content in Sesame Seed Oil
Molecules, 2023 β-carbolines (harman and norharman) are potentially mutagenic and have been reported in some vegetable oils. Sesame seed oil is obtained from roasted sesame seeds. During sesame oil processing, roasting is the key procedure to aroma enhancement, in which
Lili Shi, Ziyu Cui, Wei Liu
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Development in the Synthesis and Biological Activities of THβ-carboline and Its Analogs: Review
Ethiopian Journal of Science and Sustainable Development, 2022 1,2,3,4-Tetrahydro-β-carbolines (THβCs) are a large group of natural and synthetic indole alkaloids that possess a common tricyclic pyrido[3,4-b] indole scaffold that are widely distributed in nature.
Ayana Melaku Yadessa, Nigatu Bejigo
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Bioactivity of selected materials for coffee substitute. [PDF]
PLoS ONE, 2018 Epidemiological studies have suggested that coffee consumption is negatively correlated with the incidence of Parkinson's disease. Coffee contains relatively high levels of β-carbolines, which have been ascribed neuroactive effects in humans however the ...
Renata Zawirska-Wojtasiak +4 more
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