Results 21 to 30 of about 936,414 (160)

Synthesis of α- and β-carbolines by a etalation/Negishi cross-coupling/SNAr reaction sequence [PDF]

, 2022
A methodology for the synthesis of α- and β-carbolines from fluoropyridines and 2-haloanilines is reported. This procedure consists of a four-step directed ortho-lithiation, zincation, Negishi cross-coupling, and intramolecular nucleophilic aromatic ...
Sathiyalingam, Shainthavaan, Roesner, Stefan, Roesner, S, Stefan Roesner, Shainthavaan Sathiyalingam, Sathiyalingam, S   +5 more
core   +3 more sources

Mild and efficient ammonium chloride catalyzed Greener synthesis of tetrahydro-β-carboline

Current Research in Green and Sustainable Chemistry, 2022
This protocol involves the NH4Cl catalyzed Pictet−Spengler reactions of tryptamine and arylaldehydes in anhydrous MeOH solvent to gives corresponding tetrahydro-β-carbolines (THβC) with 90% yield. This methodology offers mild, efficient and green reagent
Milind V. Gaikwad, Sunil V. Gaikwad, Rahul D. Kamble   +2 more
doaj   +1 more source

Intramolecular C_sp²–C_sp² Friedel–Crafts Arylation: Substrate- and Condition-Controlled Divergent Synthesis of Fused-β-carbolines

, 2016
A triple cooperative catalysis-mediated multicomponent reaction between 1-formyl-N-substituted-β-carbolines, a terminal alkyne, and a secondary amine allows access to unprecedented polycyclic β-carbolines via sequential A3-coupling and an intramolecular ...
Sanjay Batra (1613422), Veena D. Yadav (3355610), Shashikant U. Dighe (1613434), Rohit Mahar (1896931), Sanjeev K. Shukla (1896934)   +4 more
core   +2 more sources

Rumors of Psychedelics, Psychotropics and Related Derivatives in Vachellia and Senegalia in Contrast with Verified Records in Australian Acacia

Plants, 2022
There are almost 1000 species of Acacia sensu stricto in Australia, while the 44 species and 4 subspecies in southern Africa were taxonomically revised in the year 2011 to Senegalia and Vachellia.
Nicholas J. Sadgrove
doaj   +1 more source

Morita–Baylis–Hillman reaction of 3-formyl-9H-pyrido[3,4-b]indoles and fluorescence studies of the products

Beilstein Journal of Organic Chemistry, 2022
β-Carboline is a privileged class of the alkaloid family and is associated with a broad spectrum of biological properties. 3-Formyl-9H-pyrido[3,4-b]indole is a such potent precursor belonging to this family which can be tailored for installing diversity ...
Nisha Devi, Virender Singh
doaj   +1 more source

Natural surfactants assisted an efficient synthesis of tetrahydro-β-carbolines

Results in Chemistry, 2021
An expeditious protocol for the synthesis of structurally diversified β-carboline derivatives has been reported using a readily available natural surfactant medium.
Somnath S. Gholap, Vinod R. Kadu
doaj   +1 more source

Biodiversity of β-Carboline Profile of Banisteriopsis caapi and Ayahuasca, a Plant and a Brew with Neuropharmacological Potential

Plants, 2020
Ayahuasca is a psychoactive infusion with a large pharmacological application normally prepared with Banisteriopsis caapi, which contains the monoamine oxidase inhibitors β-carbolines, and Psichotria virids, which contains the serotonin receptor agonist ...
Beatriz Werneck Lopes Santos, Regina Célia de Oliveira, Julia Sonsin-Oliveira, Christopher William Fagg, José Beethoven Figueiredo Barbosa, Eloisa Dutra Caldas   +5 more
doaj   +1 more source

Methodologies for the synthesis of β-carbolines [PDF]

β-Carbolines are an important class of heterocyclic compounds that are widely distributed in nature, being found in several families of naturally occurring alkaloids.
Boswood, Siobhan, Roesner, Stefan
core   +3 more sources

Diversity-oriented synthesis derived indole based spiro and fused small molecules kills artemisinin-resistant Plasmodium falciparum

Malaria Journal, 2021
Background Despite numerous efforts to eradicate the disease, malaria continues to remain one of the most dangerous infectious diseases plaguing the world. In the absence of any effective vaccines and with emerging drug resistance in the parasite against
Akshaykumar Nayak, Himani Saxena, Chandramohan Bathula, Tarkeshwar Kumar, Souvik Bhattacharjee, Subhabrata Sen, Ashish Gupta   +6 more
doaj   +1 more source

Carbenium catalysis toward β-carbolines [PDF]

, 2023
This preview highlights the findings of Liu, Jia, Loh, and co-workers, reported recently in Cell Reports Physical Science on the synthesis of β-carbolines in good to excellent yields, catalyzed by the [Ph3C]+[B(C6F5)4]− ion pair.
Richards, Emma, Melen, Rebecca L., Emma Richards, Rebecca L. Melen   +3 more
core   +1 more source