Synthesis and Herbicidal Activity Evaluation of Novel β-Carboline Derivatives
Molecules, 2012 Based on the original structure of harmine, several novel 1,2,3,4-tetrahydro-β-carboline, β-carboline and 1-substituted-β-carboline derivatives bearing a substituted carbohydrazide group at C-3 were designed and synthesized to investigate the structure ...
Qunfang Weng, Meiying Hu
exaly +4 more sources
Recent Advances in the Synthesis of β-Carboline Alkaloids
Molecules, 2021 β-Carboline alkaloids are a remarkable family of natural and synthetic indole-containing heterocyclic compounds and they are widely distributed in nature.
Timea SZABÓ +2 more
exaly +4 more sources
Synthesis and Biological Activities of C1-Substituted Acylhydrazone β-Carboline Analogues as Antifungal Candidates [PDF]
MoleculesIn our ongoing work to create potential antifungal agents, we synthesized and tested a group of C1-substituted acylhydrazone β-carboline analogues 9a–o and 10a–o for their effectiveness against Valsa mali, Fusarium solani, Fusarium oxysporum, and ...
Yujie Xu +5 more
doaj +3 more sources
Chemistry, 2022 β-carboline consists of a pyridine ring fused to an indole skeleton; it possesses numerous pharmacological activities, including anticancer. Previously, we reported a satisfactory 2D and 3D QSAR study on β-carboline derivatives. Based on QSAR studies, we
Ravindra Kumar Chourasiya +2 more
doaj +2 more sources
Studies on the syntheses of β-carboline alkaloids brevicarine and brevicolline [PDF]
Beilstein Journal of Organic ChemistryA new total synthesis of the β-carboline alkaloid brevicarine is disclosed. The synthesis was carried out starting from an aromatic triflate key intermediate, allowing the introduction of various substituents into position 4 of β-carboline by cross ...
Benedek Batizi +6 more
doaj +2 more sources
Synthesis, Antibacterial Activity, and Mechanism of C-6 Aminated β-Carboline Derivatives Against MRSA [PDF]
AntibioticsBackground: The escalating spread of drug-resistant bacteria is intensifying the antibiotic resistance crisis, necessitating the urgent development of novel antimicrobial agents to address the resulting high global mortality rates and significant ...
Qiuran Wei +9 more
doaj +2 more sources
β-Carboline Alkaloids in Soy Sauce and Inhibition of Monoamine Oxidase (MAO) [PDF]
Molecules, 2023 Monoamine oxidase (MAO) oxidizes neurotransmitters and xenobiotic amines, including vasopressor and neurotoxic amines such as the MPTP neurotoxin. Its inhibitors are useful as antidepressants and neuroprotectants.
Tomás Herraiz
doaj +2 more sources
1-Acetyl-β-Carboline from a Jeju Gotjawal Strain Lentzea sp. JNUCC 0626 and Its Melanogenic Stimulating Activity in B16F10 Melanoma Cells [PDF]
MoleculesThe genus Lentzea is a prolific source of bioactive and structurally diverse secondary metabolites. We isolated a novel strain, Lentzea sp. JNUCC 0626, from Hwasun Gotjawal on Jeju Island, Korea.
Kyung-A Hyun +3 more
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Natural surfactants assisted an efficient synthesis of tetrahydro-β-carbolines
Results in Chemistry, 2021 An expeditious protocol for the synthesis of structurally diversified β-carboline derivatives has been reported using a readily available natural surfactant medium.
Somnath S. Gholap, Vinod R. Kadu
doaj +1 more source
Results in Chemistry, 2022 β-Carbolines are of great interest due to their broad spectrum of biochemical effects and pharmaceutical functions, especially antitumor activity. The N9 position at β-carboline is a modification site for important antitumor activity. Several phenylfuran
Zhi Huang +9 more
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