Results 1 to 10 of about 1,643,257 (174)
β-Carboline Alkaloids in Soy Sauce and Inhibition of Monoamine Oxidase (MAO) [PDF]
Monoamine oxidase (MAO) oxidizes neurotransmitters and xenobiotic amines, including vasopressor and neurotoxic amines such as the MPTP neurotoxin. Its inhibitors are useful as antidepressants and neuroprotectants.
Tomás Herraiz
doaj +3 more sources
Recent Advances in the Synthesis of β-Carboline Alkaloids
β-Carboline alkaloids are a remarkable family of natural and synthetic indole-containing heterocyclic compounds and they are widely distributed in nature.
Balázs Volk +2 more
exaly +4 more sources
Vaginal lactobacilli produce anti-inflammatory β-carboline compounds. [PDF]
The vaginal microbiome is a lactobacilli-dominant, human-adapted community consistently found in people around the world. Presence of lactobacilli-dominant vaginal microbial communities, apart from Lactobacillus iners, is associated with reduced vaginal ...
Glick VJ +19 more
europepmc +2 more sources
Studies on the syntheses of β-carboline alkaloids brevicarine and brevicolline [PDF]
A new total synthesis of the β-carboline alkaloid brevicarine is disclosed. The synthesis was carried out starting from an aromatic triflate key intermediate, allowing the introduction of various substituents into position 4 of β-carboline by cross ...
Benedek Batizi +6 more
doaj +2 more sources
Newcastle disease virus (NDV) is one of the highly contagious pathogens causing devastating economic effects on the global poultry industry. In the present study, three 1-formyl-β-carboline derivatives (compounds 6, 7, and 9) were found to be potent ...
Chongyang Wang +13 more
doaj +2 more sources
Synthesis, Antibacterial Activity, and Mechanism of C-6 Aminated β-Carboline Derivatives Against MRSA [PDF]
Background: The escalating spread of drug-resistant bacteria is intensifying the antibiotic resistance crisis, necessitating the urgent development of novel antimicrobial agents to address the resulting high global mortality rates and significant ...
Qiuran Wei +9 more
doaj +2 more sources
Synthesis and Herbicidal Activity Evaluation of Novel β-Carboline Derivatives
Based on the original structure of harmine, several novel 1,2,3,4-tetrahydro-β-carboline, β-carboline and 1-substituted-β-carboline derivatives bearing a substituted carbohydrazide group at C-3 were designed and synthesized to investigate the structure ...
Qunfang Weng, Meiying Hu
exaly +3 more sources
β‑Carboline Derivatives Tackling Malaria: Biological Evaluation and Docking Analysis
Increasing resistance to presently available antimalarial drugs urges the need to look for new promising compounds. The β-carboline moiety, present in several biologically active natural products and drugs, is an important scaffold for antimalarial drug ...
Varun Gorki +6 more
doaj +2 more sources
Leishmaniasis is the most widespread pathogenic disease in several countries. Currently, no effective vaccines are available, and the control of Leishmaniasis primarily relies on decade-old chemotherapy.
Karan Kumar Banoth +4 more
doaj +2 more sources
1-Acetyl-β-Carboline from a Jeju Gotjawal Strain Lentzea sp. JNUCC 0626 and Its Melanogenic Stimulating Activity in B16F10 Melanoma Cells [PDF]
The genus Lentzea is a prolific source of bioactive and structurally diverse secondary metabolites. We isolated a novel strain, Lentzea sp. JNUCC 0626, from Hwasun Gotjawal on Jeju Island, Korea.
Kyung-A Hyun +3 more
doaj +2 more sources

