Results 21 to 30 of about 867,980 (166)

Morita–Baylis–Hillman reaction of 3-formyl-9H-pyrido[3,4-b]indoles and fluorescence studies of the products

Beilstein Journal of Organic Chemistry, 2022
β-Carboline is a privileged class of the alkaloid family and is associated with a broad spectrum of biological properties. 3-Formyl-9H-pyrido[3,4-b]indole is a such potent precursor belonging to this family which can be tailored for installing diversity ...
Nisha Devi, Virender Singh
doaj   +1 more source

Regioselective Decarboxylative Transformations of Tetrahydro--carboline-1-carboxylic Acid: Reagent Controlled Selectivity toward Alkynylated or Enaminone Products

, 2023
A one-pot, regioselective decarboxylative alkynylation of tetrahydro-β-carboline-1-carboxylic acid under peroxide-free condition is reported. The reaction is highly selective for the 1-position over the 3-position of tetrahydro-β-carboline.
Subhendu Bhowmik, Md Imran Ahmed (17094096), Arka Das, Arka Das (16681594), Subhendu Bhowmik (1903357), Md Imran Ahmed, Christine Jonathan, Christine Jonathan (17094093), Rana Saha, Rana Saha (2040913)   +9 more
core   +1 more source

Increased β-Carboline 9N-Methyltransferase Activity in the Frontal Cortex in Parkinson's Disease

Neurobiology of Disease, 2000
Enzymatic β-carboline N-methyltransferase activities generate N-methylated β-carbolinium cations that are analogs of the parkinsonian-producing neurotoxin MPP+.
Debra A. Gearhart, Michael A. Collins, John M. Lee, Edward J. Neafsey   +3 more
doaj   +1 more source

Synthesis, In Vitro Antiproliferative And Anti-mycobacterium Tuberculosis Activities Of Novel β-carboline Derivatives [PDF]

, 2017
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)A series of β-carboline derivatives with amino or guanidinium were synthesized and evaluated in vitro against anti ...
Ruiz A.L.T.G., Moreira F.M.F., Sarragiotto M.H., Formagio A.S.N., Carvalho J.E., Croda J., Foglio M.A.   +6 more
core   +3 more sources

A new β-carboline-type alkaloid from the flowers of Calotropis gigantea (L.) W.T.Aiton

, 2023
In our antioxidant screening of some Vietnamese plant extracts, the CHCl3-soluble fraction from Calotropis gigantea (L.) W.T.Aiton flowers showed moderate DPPH free radical scavenging activity with an IC50 value of 55.8 μg/mL.
Tho H. Le (4067821), Mai T. T. Nguyen (7255331), Nhan T. Nguyen (4067830), Tu H. Tran (10317256), Phu H. Dang (4067818), Truong N. V. Do (7255328), Hai X. Nguyen (4067812)   +6 more
core   +1 more source

Preparative Separation of Alkaloids from Picrasma quassioides (D. Don) Benn. by Conventional and pH-Zone-Refining Countercurrent Chromatography

Molecules, 2014
Two high-speed countercurrent chromatography (HSCCC) modes were compared by separation of major alkaloids from crude extract of Picrasma quassioides. The conventional HSCCC separation was performed with a two-phase solvent system composed of petroleum ...
Qinghai Zhang, Xikai Shu, Feng Jing, Xiao Wang, Changhu Lin, Aiqin Luo   +5 more
doaj   +1 more source

Orthoscuticellines A–E, β-Carboline Alkaloids from the Bryozoan Orthoscuticella ventricosa Collected in Australia

, 2020
Antiplasmodial high-throughput screening of extracts derived from marine invertebrates collected from northern NSW, Australia, resulted in the methanol extract of the bryozoan Orthoscuticella ventricosa being identified as inhibitory toward the 3D7 ...
Kleks, Guy, Lucantoni, Leonardo, Carroll, Anthony R, Avery, Vicky M, Duffy, Sandra   +4 more
core   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +2 more sources

Synthesis and Antimicrobial Activities of 3-Methyl-β-Carboline Derivatives

Natural Product Communications, 2015
The β-carboline alkaloids possess a diverse range of important biochemical effects and pharmacological properties. Sixteen 3-methyl-β-carboline derivatives were synthesized from indole formaldehyde and nitroethane via the Henry reaction, LAH/THF ...
Jiwen Zhang, Longbo Li, Wenjia Dan, Jian Li, Qianliang Zhang, Hongjin Bai, Junru Wang   +6 more
doaj   +1 more source

Formation, Characterization, and Occurrence of β-Carboline Alkaloids Derived from α-Dicarbonyl Compounds and l-Tryptophan

, 2022
[Image: see text] β-Carbolines (βCs) are naturally occurring bioactive alkaloids, whereas α-dicarbonyl compounds are reactive substances generated in foods and in vivo.
Herraiz, Tomás, Herraiz, Marta, Marta Herraiz, Peña, Adriana, Tomás Herraiz, Haroll Mateo, Antonio Salgado, Mateo, Haroll, Salgado, Antonio, Herraiz Tomico, Tomás, Herraiz Carasa, Marta, Adriana Peña   +11 more
core   +1 more source