Synthesis and Antimicrobial Activities of 3-Methyl-β-Carboline Derivatives
Natural Product Communications, 2015 The β-carboline alkaloids possess a diverse range of important biochemical effects and pharmacological properties. Sixteen 3-methyl-β-carboline derivatives were synthesized from indole formaldehyde and nitroethane via the Henry reaction, LAH/THF ...
Jiwen Zhang +6 more
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Inhibiting β-Catenin by β-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy
Frontiers in Pharmacology, 2018 The β-catenin and MDM2 oncoproteins are overexpressed and constitutively activated in human pancreatic cancer and contribute to its initiation, progression, and metastasis.
Jiang-Jiang Qin +7 more
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Frontiers in Immunology, 2022 β-Carbolines are potentially strong alkaloids with a wide range of bioactivities, and their dimers exhibit stronger antitumor activity other than the monomers. However, the detailed mechanisms of the β-carboline dimers in inhibiting sarcoma (SARC) remain
Huiya Ma +9 more
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Production of Induced Secondary Metabolites by a Co-Culture of Sponge-Associated Actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163 [PDF]
, 2014 Two sponge-derived actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163, were grown in co-culture and the presence of induced metabolites monitored by ¹H NMR.
Abdelmohsen, Usama +4 more
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LC/MS/MS analysis of the endogenous dimethyltryptamine hallucinogens, their precursors, and major metabolites in rat pineal gland microdialysate [PDF]
, 2013 We report a qualitative liquid chromatography–tandem mass spectrometry (LC/MS/MS) method for the simultaneous analysis of the three known N , N ‐dimethyltryptamine endogenous hallucinogens, their precursors and metabolites, as well as melatonin and its ...
Barker, Steven A. +3 more
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Heliyon, 2020 Leishmaniasis is the most widespread pathogenic disease in several countries. Currently, no effective vaccines are available, and the control of Leishmaniasis primarily relies on decade-old chemotherapy.
Karan Kumar Banoth +4 more
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Cholinesterase Enzymes Inhibitors from the Leaves of Rauvolfia Reflexa and Their Molecular Docking Study [PDF]
, 2013 molecule
A. Hadi +5 more
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Bulletin of Faculty of Pharmacy Cairo University, 2011 An efficient in vitro production of biomass hairy root cultures and elicitation of β-carboline alkaloids of Peganum harmala was established from P. harmala seedlings. Hairy root culture was arised by inoculation of the excised seedling with Agrobacterium
Rawia Zayed
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Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action. [PDF]
, 2013 The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this review, following the format used in the 1998–2008 reviews of this series.
A. D. Rodriguez +3 more
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Current Research in Food Science, 2023 The effect of quercetin and oil water separation system on the formation of heterocyclic amines (HAs) was investigated during the frying process of braised chicken drumsticks.
Xuefei Li +5 more
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