Results 41 to 50 of about 8,115 (178)

Mechanistic insights into a BINOL-derived phosphoric acid-catalyzed asymmetric Pictet-Spengler reaction. [PDF]

open access: yes, 2015
The reaction of tryptamine and (2-oxocyclohexyl)acetic acid can be catalyzed by 3,3'-bis(triphenylsilyl)-1,1'-bi-2-naphthol phosphoric acid to give an asymmetric β-carboline. This reaction was first studied by Holloway et al. ( Org. Lett.
Goodman, Jonathan M   +3 more
core   +3 more sources

Dual Acid Responses of Stable Luminescent Diphenylpyridylmethyl Radicals With Additional Pyridyl Groups

open access: yesChemistry – A European Journal, EarlyView.
To expand the acid‐responsive behavior of diphenylpyridylmethyl stable luminescent radicals, additional pyridyl groups were introduced. Dual acid responsiveness was observed, involving both the newly incorporated pyridyl groups and the PyBTM moieties.
Yohei Hattori   +3 more
wiley   +1 more source

Review of β-carboline Alkaloids from the Genus

open access: yesNatural Product Communications, 2015
Plants belonging to the genus Aspidosperma , a member of the family Apocynaceae, provide a rich source of β-carboline alkaloids, which makes them potentially poisonous. However, some of these alkaloids possess antitumor and antimicrobial activity.
Tanya H. Layne   +2 more
doaj   +1 more source

Cytotoxic and Insecticidal Activities of Derivatives of Harmine, a Natural Insecticidal Component Isolated from Peganum harmala

open access: yesMolecules, 2010
In a continuing effort to develop novel β-carbolines endowed with better insecticidal activity, a simple high-yielding method for the synthesis of harmine compounds starting from L-tryptophan has been developed and a series of 1,3-substituted β-carboline
Guohua Zhong   +4 more
doaj   +1 more source

Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Interest in ayahuasca and its main component, N,N‐Dimethyltryptamine (DMT), has currently moved from historical and experimental use into modern clinical development. Yet, current evidence is fragmented, and systematic mapping of trial methods and design choices remains limited.
Tijana Stojanović   +4 more
wiley   +1 more source

Binding of harmane to human and bovine serum albumin: fluorescence and phosphorescence study [PDF]

open access: yes, 2012
The binding of harmane with human serum albumin (HSA) and bovine serum albumin (BSA) were studied by fluorescence and phosphorescence spectroscopic methods. Quenching of fluorescence of serum albumins by harmane was found to be a static quenching process.
Despotović, Biljana   +6 more
core  

Effect of hydrogen bonding and complexation with metal ions on the fluorescence of luotonin A [PDF]

open access: yes, 2013
Fluorescence characteristics of a biologically active natural alkaloid, luotonin A (LuA), were studied by steady-state and time-resolved spectroscopic methods.
Abraham   +45 more
core   +1 more source

Total Synthesis of rac‐Keramamine C Enabled by Intrinsic H‐Bond‐Induced Conformational Fixation of Amides

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The total synthesis of the manzamine alkaloid keramamine C (2) in its racemic form was achieved in 5 steps, with ring‐closing metathesis as the key step. The metathesis is strongly improved by an intramolecular H‐bond‐induced conformational fixation of the amide bond, inducing close proximity of the terminal double bonds in the precursor molecule.
Jana Ganzmann   +4 more
wiley   +1 more source

Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids

open access: yesNature Communications
Tetrahydro-β-carboline skeletons are prominent and ubiquitous in an extraordinary range of indole alkaloid natural products and pharmaceutical compounds. Powerful synthetic approaches for stereoselective synthesis of tetrahydro-β-carboline skeletons have
Xiaochen Tian   +9 more
doaj   +1 more source

Candida antarctica lipase-catalyzed synthesis and characterization of novel acrylic teroligomers [PDF]

open access: yes, 2018
The synthesis of three novel low molecular weight acrylic terpolymers, containing at random sequences of ethyl acrylate, acrylic acid and N-(2-hydroxyethyl)acrylamide, catalyzed by Candida antarctica lipase was successfully conducted in organic media ...
Baldessari, Alicia   +4 more
core  

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