Results 61 to 70 of about 3,969 (129)

Synthesis and Bioactivity of β-Carboline Derivatives

Natural Product Communications, 2010
The β-carboline alkaloids possess a wide diversity of important biochemical effects and pharmacological properties. A series of β-carboline derivatives were synthesized from L-tryptophan through the Pictet-Spengler reaction and oxidation of K 2 Cr 2 O 7 ...
Shengkun Li, Bing Yang, Qianliang Zhang, Jiwen Zhang, Junru Wang, Wenjun Wu   +5 more
doaj   +1 more source

Dual-pathway detoxification by Dendrobium nobile Lindl. Polysaccharide: concurrent suppression of bound heterocyclic amine release and heterocyclic amine-elicited cytotoxicity during gastrointestinal digestion

Food Chemistry: X
This study investigated Dendrobium nobile Lindl. polysaccharides (DNP) for their effects on bound heterocyclic amine (HAs) release in beef patties, myofibrillar protein (MP) and sarcoplasmic protein (SP) models.
Yi Le, Chenxia Zhang, Jinrun Xiao, Huirong Lei, Wei Quan, Hongkang Zhu, Siwei Xiong, Jun Sheng, Peiyuan Sun, Huanhuan Xu, Chaoyi Xue   +10 more
doaj   +1 more source

7-Bromo-1-ethyl-β-carboline, an Alkaloid from the New Zealand Marine Bryozoan

Natural Product Communications, 2013
A new alkaloid, 7-bromo-1-ethyl-β-carboline ( 1 ) has been isolated from the New Zealand marine bryozoan Pterocella vesiculosa (Lamarck, 1816). Structural elucidation was achieved through NMR spectroscopic and mass spectrometric analysis.
Michèle R. Prinsep, Mérine Dumté
doaj   +1 more source

Comprehensive phytochemical study of Galianthe thalictroides: isolation of three new compounds, structural revision of β-carbolines, and evaluation of cytotoxic and anti-wnt activities

Frontiers in Natural Products
IntroductionThe medicinal plant G. thalictroides (K. Schum.) E. L. Cabral has been traditionally used in Midwestern Brazil for cancer treatment and prevention.
Patrícia de Oliveira Figueiredo, Patrícia de Oliveira Figueiredo, Patrícia de Oliveira Figueiredo, Olivier August Kirchhoffer, Olivier August Kirchhoffer, Laurence Marcourt, Laurence Marcourt, Luis Quiros-Guerrero, Luis Quiros-Guerrero, Alexey Koval, Wilson Hino Kato Junior, Nídia Cristiane Yoshida, Fernanda Rodrigues Garcez, Walmir Silva Garcez, Vladimir L. Katanaev, Vladimir L. Katanaev, Jean-Luc Wolfender, Jean-Luc Wolfender, Emerson Ferreira Queiroz, Emerson Ferreira Queiroz   +19 more
doaj   +1 more source

β-carboline derivative Z86 alleviates pulmonary fibrosis via suppressing TGF-β/Smad signaling. [PDF]

Nat Prod Bioprospect
Wang Y, Zhang S, Geng R, Wang R, Huang Y, Xu G, Kong L, Li Y.   +7 more
europepmc   +1 more source

Synthesis of Tetrahydro-β-Carboline-Based Spirocyclic Peptides via Cascade N-Boc Deprotection and Pictet-Spengler Reaction of Tryptophan: Potent Anti-Inflammatory and Anti-Oxidant Activities. [PDF]

Drug Dev Res
Battula S, Kambhampati V, Andugulapati SB, Nayani K.   +3 more
europepmc   +1 more source

β‑Carboline Derivatives Tackling Malaria: Biological Evaluation and Docking Analysis

ACS Omega, 2020
Varun Gorki, Neha Sylvia Walter, Rahul Singh, Monika Chauhan, Neelima Dhingra, Deepak B. Salunke, Sukhbir Kaur   +6 more
doaj   +1 more source

Structural basis of regioselective double halogenation of the β-carboline tryptoline by the single-component halogenase AetF. [PDF]

Acta Crystallogr D Struct Biol
Bork S, Horstmeier HJ, Scharkowski B, Niemann HH.   +3 more
europepmc   +1 more source

A β-carboline natural product induces oxidative stress in <i>Fusarium graminearum</i> and limits the virulence of multiple fungal phytopathogens. [PDF]

mBio
Laflamme B, Blackman C, Ryder L, Loranger MEW, Ma W, Lee Y, Balcerzak M, MacAlpine J, Whitesell L, Talbot NJ, Yoshioka K, Subramaniam R, Robbins N, Cowen LE.   +13 more
europepmc   +1 more source

Design, synthesis, and anti-Toxoplasma gondii evaluation of β-carboline derivatives. [PDF]

Parasit Vectors
Liu Z, Li Y, Li Y, Han X, Qiu H, Qin C, Zhu Y, Liang W, Mo J, Yan Z, Gao W, Zhang J, Zheng J, Liang H, Zhang J.   +14 more
europepmc   +1 more source