Results 81 to 90 of about 8,115 (178)

BoneMicro-CT Assessments in an Orchidectomised RatModel Supplemented with Eurycoma longifolia [PDF]

, 2012
Recent studies suggested that Eurycoma longifolia, a herbal plant, may have the potential to treat osteoporosis in elderly male. This study aimed to determine the effects of Eurycoma longifolia supplementation on the trabecular bone microarchitecture ...
Khamis, Mohd Fadhli, Ramli, Rosmaliza, Shuid, Ahmad Nazrun   +2 more
core   +3 more sources

Orthoquinone, Cyclic, and Acyclic α‐Diketone Natural Products: From Food Applications to Pharmacotherapy

Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
The orthoquinone metabolites from plants have antimicrobial, antioxidant, antiviral, cytotoxic, and anti‐inflammatory effects. ABSTRACT The structural diversity of natural products is vast and fascinating, and they have been recognized as an enormously diverse source of new lead compounds.
Hidayat Hussain, Daijie Wang, Satyajit D. Sarker, Lutfun Nahar, Nilufar Z. Mamadalieva, Jianbo Xiao   +5 more
wiley   +1 more source

An Enzymatic Cyclopentyl[b]indole Formation Involved in Scytonemin Biosynthesis [PDF]

, 2014
Previous studies of the biosynthetic enzymes involved in the assembly of scytonemin (1), a cyanobacterial sunscreen, have identified β-ketoacid 2 as an important intermediate that is produced by ThDP-dependent enzyme ScyA.
Balskus, Emily Patricia, Walsh, Christopher T.   +1 more
core   +1 more source

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of β-Carboline and Quinoline Alkaloids Derivatives from the Plants of Genus Peganum

Journal of Chemistry, 2013
It was reported that the main chemical constituents in plants of genus Peganum were a serial of β-carboline and quinoline alkaloids. These alkaloids were quantitatively assessed for selective inhibitory activities on acetylcholinesterase (AChE) and ...
Ting Zhao, Ke-min Ding, Lei Zhang, Xue-mei Cheng, Chang-hong Wang, Zheng-tao Wang   +5 more
doaj   +1 more source

Quality Assessment of Kumu Injection, a Traditional Chinese Medicine Preparation, Using HPLC Combined with Chemometric Methods and Qualitative and Quantitative Analysis of Multiple Alkaloids by Single Marker

Molecules, 2018
Kumu injection (KMI) is a common-used traditional Chinese medicine (TCM) preparation made from Picrasma quassioides (D. Don) Benn. rich in alkaloids.
Ning Wang, Zhi-Yong Li, Xiao-Li Zheng, Qiao Li, Xin Yang, Hui Xu   +5 more
doaj   +1 more source

بررسی سميت سلولی عصاره دانه گياه اسفند و ارتباط آن با ميزان آلکالوئيدهای بتا ـ کاربولينی موجود در عصاره [PDF]

, 2002
عصاره دانه گياه اسفند ( Peganum harmala L. ) از جمله اجزای تشکيل دهنده يکی از فرآورده‌های گياهی بومی بکار رفته جهت درمان سرطان در ايران است. آلکالوئيدهای بتا ـ کاربولينی نظير هارمين و هارمالين قسمت اعظم ترکيبات فعال موجود در اسفند را تشکيل می‌دهند.
احمد ابراهيمی, سلطان, رهبر روشندل, ناهید, محموديان, مسعود, مددکارسبحانی, آرمین, هورمند, محمود   +4 more
core  

Clogging the Ubiquitin-Proteasome Machinery with Marine Natural Products: Last Decade Update. [PDF]

, 2018
The ubiquitin-proteasome pathway (UPP) is the central protein degradation system in eukaryotic cells, playing a key role in homeostasis maintenance, through proteolysis of regulatory and misfolded (potentially harmful) proteins.
Agriesti, F., Costantino, V., Della Sala, G., Mazzoccoli, C., Piccoli,, Tataranni, T.   +5 more
core   +1 more source

β-carboline alkaloids from Stellaria dichotoma as anti-fibrotic therapeutics against chronic kidney disease

Industrial Crops and Products
β-Carboline alkaloids possess significant industrial value and considerable potential for drug development. In pursuit of potential therapeutic agents for chronic kidney disease (CKD), twenty-one β-carboline alkaloids (1–21), including seven new β ...
Bixuan Cao, Zengguang Zhang, Ye Kang, Hang Lv, Mimi Zhang, Ping Yi, Li Han, Zhongyuan Liu, Xueshi Huang   +8 more
doaj   +1 more source

Synthesis and Evaluation of New β-Carboline-3-(4-benzylidene)-<em>4H</em>-oxazol-5-one Derivatives as Antitumor Agents

Molecules, 2012
In the present work, we report the synthesis and<em> in vitro</em> anticancer and antimicrobial activity evaluation of a new series of 1-substituted-β-carboline derivatives<strong> </strong>bearing a 4-benzylidene-<em>4H-<
Maria Helena Sarragiotto, Emerson Meyer, Marta C. T. Duarte, Mauricio Ferreira da Rosa, João Ernesto de Carvalho, Ana Lúcia T. G. Ruiz, Mary Ann Foglio, Franciele Cristina Savariz   +7 more
doaj   +1 more source

Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin. [PDF]

, 2017
Despite being an invaluable chemotherapeutic agent for several types of cancer, the clinical utility of doxorubicin is hampered by its age-related and dose-dependent cardiotoxicity.
Ashour, M.E., Atteya, R., El-Khamisy, S.F., Farag, M.A., Ibrahim, E.E.   +4 more
core   +1 more source