Results 71 to 80 of about 700,501 (169)

First total synthesis of β-carboline alkaloid trigonostemine G and its derivatives

, 2019
The β-carboline core is the base structure of several biologically active natural and unnatural compounds. Herein, we report the first total synthesis of trigonostemine G, which is a newly isolated natural β-carboline alkaloid from the twigs of ...
Balázs Volk (2441869), Tímea Szabó (6750839), András Dancsó (6750842), Mátyás Milen (6750845)   +3 more
core   +1 more source

Chemical Constituents from the Flower of Hosta plantaginea with Cyclooxygenases Inhibition and Antioxidant Activities and Their Chemotaxonomic Significance

Molecules, 2017
Two new phenolic glucosides, hostaflavanone A (1) and anti-1-phenylpropane-1,2-diol-2-O-β-d-glucopyranoside (2), together with six known compounds, anti-1-phenylpropane-1,2-diol (3), phenethyl-O-β-d-glucopyranoside (4), phenethanol-β-d-gentiobioside (5),
Li Yang, Shu-Tai Jiang, Qin-Guang Zhou, Guo-Yue Zhong, Jun-Wei He   +4 more
doaj   +1 more source

Inhibitory Activity of Conferone on FAK Activity and Glutamine Metabolism in Human Colorectal Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Colorectal cancer (CRC) is a major global cause of death, with metastases and chemotherapy resistance contributing to poor outcomes. To identify natural compounds with anticancer potential against CRC and elucidate their action mechanisms, the cytotoxicity of 37 natural compounds was evaluated against the HCT116, leading to the identification ...
Hien Thi My Ong, Eda Ates, Jaeyong Jung, Jeong Soo Sung, Jae‐Chul Pyun, Min‐Jung Kang   +5 more
wiley   +1 more source

Synthesis and in vitro evaluation of ¹⁸F-β-carboline alkaloids as PET ligands

, 2008
A one-step 18F-labelling strategy was used to prepare four 18F-labelled analogues of 7-methoxy-1-methyl-9H-β-carboline (harmine): 7-(2-[18F]fluoroethoxy)-1-methyl-9H-β-carboline (5), 7-(3-[18F]fluoro-propoxy)-1-methyl-9H-β-carboline (6), 7-[2-(2-[18F ...
Eriksson, Olof,, Karimi, Farhad,, Blom, Elisabeth,, Långström, Bengt,, Hall, Håkan   +4 more
core   +1 more source

Effects of tryptophan derivatives and β -carboline alkaloids on radiation- and peroxide-induced transformations of ethanol

, 2014
The subject of this study was investigation of interactions of tryptophan and its derivatives, including structurally related β-carboline alkaloids with oxygen- and carbon-centered radicals being formed during radiation- and peroxide-induced ...
Brinkevich, S. D., Shadyro, O. I., Sverdlov, R. L.   +2 more
core   +1 more source

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of β-Carboline and Quinoline Alkaloids Derivatives from the Plants of Genus Peganum

Journal of Chemistry, 2013
It was reported that the main chemical constituents in plants of genus Peganum were a serial of β-carboline and quinoline alkaloids. These alkaloids were quantitatively assessed for selective inhibitory activities on acetylcholinesterase (AChE) and ...
Ting Zhao, Ke-min Ding, Lei Zhang, Xue-mei Cheng, Chang-hong Wang, Zheng-tao Wang   +5 more
doaj   +1 more source

Quality Assessment of Kumu Injection, a Traditional Chinese Medicine Preparation, Using HPLC Combined with Chemometric Methods and Qualitative and Quantitative Analysis of Multiple Alkaloids by Single Marker

Molecules, 2018
Kumu injection (KMI) is a common-used traditional Chinese medicine (TCM) preparation made from Picrasma quassioides (D. Don) Benn. rich in alkaloids.
Ning Wang, Zhi-Yong Li, Xiao-Li Zheng, Qiao Li, Xin Yang, Hui Xu   +5 more
doaj   +1 more source

Synthesis and Characterization of the Food-Derived Carcinogens 2-(Hydroxylamino)-α-carboline and 2-(Hydroxylamino)-3-methyl-α-carboline

, 2016
Synthesis and Characterization of the Food-Derived Carcinogens 2-(Hydroxylamino)-α-carboline and 2-(Hydroxylamino)-3-methyl-α ...
Shahrokh Kazerani (3008535), Michael Novak (1691365)   +1 more
core   +1 more source

β-carboline alkaloids from Stellaria dichotoma as anti-fibrotic therapeutics against chronic kidney disease

Industrial Crops and Products
β-Carboline alkaloids possess significant industrial value and considerable potential for drug development. In pursuit of potential therapeutic agents for chronic kidney disease (CKD), twenty-one β-carboline alkaloids (1–21), including seven new β ...
Bixuan Cao, Zengguang Zhang, Ye Kang, Hang Lv, Mimi Zhang, Ping Yi, Li Han, Zhongyuan Liu, Xueshi Huang   +8 more
doaj   +1 more source

Synthesis and Evaluation of New β-Carboline-3-(4-benzylidene)-<em>4H</em>-oxazol-5-one Derivatives as Antitumor Agents

Molecules, 2012
In the present work, we report the synthesis and<em> in vitro</em> anticancer and antimicrobial activity evaluation of a new series of 1-substituted-β-carboline derivatives<strong> </strong>bearing a 4-benzylidene-<em>4H-<
Maria Helena Sarragiotto, Emerson Meyer, Marta C. T. Duarte, Mauricio Ferreira da Rosa, João Ernesto de Carvalho, Ana Lúcia T. G. Ruiz, Mary Ann Foglio, Franciele Cristina Savariz   +7 more
doaj   +1 more source