Results 91 to 100 of about 8,115 (178)

In Vitro and In Silico Studies on the Anti-H1N1 Activity of Bioactive Compounds from Marine-Derived Streptomyces ardesiacus

Marine Drugs
This study explores the potential anti-H1N1 Influenza A activity of bioactive compounds extracted from Streptomyces ardesiacus, a marine-derived microorganism known for producing diverse secondary metabolites.
Yung-Husan Chen, Cheng-Yang Hsieh, Chun-Tang Chiou, Engelo John Gabriel V. Caro, Lemmuel L. Tayo, Po-Wei Tsai   +5 more
doaj   +1 more source

A review study of therapeutic effects of Peganum harmala [PDF]

, 2016
Peganum harmala. belongs to Asian Origin and grows in the Middle East and in part of South mainly in India and Pakistan, is a plant of the family Nitrariaceae. It is a perennial plant which can grow to about 0.8 m tall.
Miraj, S.
core  

Alkaloids, Coumarins and Lignans from Haplophyllum Species [PDF]

, 2008
Although there are a number of Haplophyllum species in the world, H. acutifolium (DC.) G. Don, H. buxbaumii (Poiret) G.Don, H. buxbaumii (Poiret) G.Don, subsp. Buxbaumii, H. cappadocium Spach, H. glabrinum, H. hispanicum Sprach, H. myrtifolium Boiss., H.
Ayhan Ulubelen, Mehmet Öztürk
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Synthesis, Antibacterial Activity, and Mechanism of C-6 Aminated β-Carboline Derivatives Against MRSA

Antibiotics
Background: The escalating spread of drug-resistant bacteria is intensifying the antibiotic resistance crisis, necessitating the urgent development of novel antimicrobial agents to address the resulting high global mortality rates and significant ...
Qiuran Wei, Weida Liang, Hongda Qiu, Xing Zhao, Yang Li, Han Ouyang, Bowen Han, Lingling Zhao, Xiao Wang, Hongze Liang   +9 more
doaj   +1 more source

Seasonal changes in antioxidative/oxidative profile of mining and non-mining populations of Syrian beancaper as determined by soil conditions [PDF]

, 2017
Soil pollution by heavy metals/metalloids (HMMs) is a problem worldwide. To prevent dispersion of contaminated particles by erosion, the maintenance of a vegetative cover is needed.
Bueso Sánchez, María del Carmen, Calderón García, Antonio Asensio, Conesa Alcaraz, Héctor Miguel, Ferrer Ayala, María Ángeles, López Orenes, Antonio   +4 more
core   +2 more sources

The cyanobacterial alkaloid nostocarboline: an inhibitor of acetylcholinesterase and trypsin [PDF]

, 2018
Preselected cyanobacterial strains (available from culture collections and our own isolates), belonging primarily to the heterocystous cluster, were screened for inhibitors against butyrylcholinesterase.
Baumann, Heike, Becher, Paul, Gademann, Karl, Jüttner, Friedrich   +3 more
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Ethnomedicines and anti-parasitic activities of Pakistani medicinal plants against Plasmodia and Leishmania parasites [PDF]

, 2016
BACKGROUND: Leishmaniasis and malaria are the two most common parasitic diseases and responsible for large number of deaths per year particularly in developing countries like Pakistan. Majority of Pakistan population rely on medicinal plants due to their
Akash Tariq, Kaiwen Pan, Muhammad Adnan, Rahila Amber, Sakina Mussarat, Zabta Khan Shinwari   +5 more
core   +1 more source

Synthesis, ADME, and In Silico Molecular Docking Study of Novel N-Substituted β-Carboline Analogs as a Potential Anticancer Agent

Chemistry Proceedings
The present study designed and computationally optimized a series of novel β-carboline derivatives to investigate the interaction between designed ligands and selected proteins.
Sunil Gaikwad
doaj   +1 more source

A Facile Synthesis of 3-Substituted 9H-Pyrido[3,4-b]indol-1(2H)-one Derivatives from 3-Substituted β-Carbolines

Molecules, 2010
A mild and efficient two-step synthesis of 3-substituted β-carbolinone derivatives from 3-substituted β-carboline in good yields is described. A possible reaction mechanism for the formation of the skeleton of β-carbolin-1-one is proposed. The structures
Tao Lu, Jian Wang, Qingfa Zhou, Weifang Tang, Yue Wang, Guowu Lin   +5 more
doaj   +1 more source

Synthesis and biological evaluation of novel N9-heterobivalent β-carbolines as angiogenesis inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
A series of novel N9-heterobivalent β-carbolines has been synthesized. All the novel compounds were tested for their anticancer activity against six tumour cell lines in vitro.
Liang Guo, Qin Ma, Wei Chen, Wenxi Fan, Jie Zhang, Bin Dai   +5 more
doaj   +1 more source