Antimicrobial Activity of Actinobacteria Isolated From Kratom (Mitragyna speciosa) Leaves: Secondary Metabolite Profiling and Genome Analysis of Micromonospora chersina NRAIS18 [PDF]
International Journal of MicrobiologyActinobacteria associated with medicinal plants are recognized as prolific sources of novel bioactive compounds. Kratom (Mitragyna speciosa) leaves have been reported to contain a diverse array of secondary metabolites with pharmacological activities ...
Nittaya Pitiwittayakul +3 more
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Bioactive β-Carbolines Harman and Norharman in Sesame Seed Oils in China
Molecules, 2022 The β-carbolines in our diet, mainly including harman and norharman, are a group of biologically active, naturally occurring plant-derived alkaloids. Fragrant sesame seed oil is one of the most popular flavor edible oils in China. Considering that sesame
Wei Liu, Zhaoyu Yang, Lili Shi, Yun Li
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The Effects of Prenatal Norharman Exposure on Seizure Severity in Rats [PDF]
The Journal of Qazvin University of Medical Sciences, 2021 Background: Norhraman is an alkaloid that can damage the nervous system. Objective: This experimental study aimed to investigate the effects of prenatal norharman exposure on seizure severity in adult rats.
Mohammad Hossein Esmaeili +2 more
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Harman and norharman, metabolites of entomopathogenic fungus Conidiobolus coronatus (Entomopthorales), disorganize development of Galleria mellonella (Lepidoptera) and affect serotonin-regulating enzymes. [PDF]
PLoS ONE, 2018 Naturally occurring entomopathogenic fungi such as Conidiobolus coronatus are important regulatory factors of insect populations. GC-MS analysis of fungal cell-free filtrates showed that C.
Anna Katarzyna Wrońska +3 more
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Cell & Bioscience, 2019 Background Although the β-carboline alkaloids harman and norharman are considered as plant metabolites, they can also be secreted by fungi such as the entomopathogen Conidiobolus coronatus. Norharman and harman are also known to be reversible competitive
Anna Katarzyna Wrońska +1 more
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Application of fused-grid-based CYP-Template systems for genotoxic substances to understand the metabolisms [PDF]
Genes and Environment, 2023 Understanding of metabolic processes is a key factor to evaluate biological effects of carcinogen and mutagens. Applicability of fused-grid Template* systems of CYP enzymes (Drug Metab Pharmacokinet 2019, 2020, 2021, and 2022) was tested for three ...
Yasushi Yamazoe +3 more
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Effects of Oil and Processing Conditions on Formation of Heterocyclic Amines and Polycyclic Aromatic Hydrocarbons in Pork Fiber [PDF]
Foods, 2023 Toxic compounds such as heterocyclic amines (HAs) and polycyclic aromatic hydrocarbons (PAHs) can be produced during food processing, especially meat products.
Yu-Wen Lai +2 more
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Secondary metabolites of Minutisphaera thailandensis and Hongkongmyces kokensis revealed by LC–QTOF–MS and their antimicrobial and cytotoxic activities [PDF]
Scientific ReportsThe mycelial extracts of two novel fungal species, Minutisphaera thailandensis and Hongkongmyces kokensis, were investigated for their antimicrobial, cytotoxic, and secondary metabolite profiles to assess their potential as sources of bioactive natural ...
Sarunpron Khruengsai +3 more
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Analysis of Polycyclic Aromatic Hydrocarbons via GC-MS/MS and Heterocyclic Amines via UPLC-MS/MS in Crispy Pork Spareribs for Studying Their Formation during Frying [PDF]
FoodsThis study aims to explore the effects of frying conditions on the formation of HAs and PAHs in crispy pork spareribs, a popular meat commodity sold on Taiwan’s market.
Yu-Wen Lai +2 more
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Development of a Novel, Simultaneous Determination Method for Heterocyclic Amines and Mycotoxins in Fried Food by UPLC-MS/MS Combined With QuEChERS. [PDF]
Food Sci Nutr• A novel QuEChERS‐UPLC‐MS/MS method was successfully developed for the simultaneous determination of two β‐carboline heterocyclic amines and seven mycotoxins in fried foods. ABSTRACT Dietary exposure to both processing contaminants and natural toxins in fried foods poses a potential health risk, but analytical methods for their simultaneous monitoring
Yang D +6 more
europepmc +2 more sources