Antimicrobial Activity of Actinobacteria Isolated From Kratom (Mitragyna speciosa) Leaves: Secondary Metabolite Profiling and Genome Analysis of Micromonospora chersina NRAIS18 [PDF]
International Journal of MicrobiologyActinobacteria associated with medicinal plants are recognized as prolific sources of novel bioactive compounds. Kratom (Mitragyna speciosa) leaves have been reported to contain a diverse array of secondary metabolites with pharmacological activities ...
Nittaya Pitiwittayakul +3 more
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Trait Anxiety, Coping with Stress, and Norharman [PDF]
Psychological Reports, 1997 Plasma levels of the β-carboline norharman, concentration of platelet 5-HT, trait measures of anxiety, and measures of coping and defense mechanisms were compared for 15 patients with panic disorder and 24 healthy volunteers. Patients indicated that they made less use of the defense mechanism of principalization than control subjects.
Verheij, René +4 more
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The Effects of Prenatal Norharman Exposure on Seizure Severity in Rats [PDF]
The Journal of Qazvin University of Medical Sciences, 2021 Background: Norhraman is an alkaloid that can damage the nervous system. Objective: This experimental study aimed to investigate the effects of prenatal norharman exposure on seizure severity in adult rats.
Mohammad Hossein Esmaeili +2 more
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Harman and norharman, metabolites of entomopathogenic fungus Conidiobolus coronatus (Entomopthorales), disorganize development of Galleria mellonella (Lepidoptera) and affect serotonin-regulating enzymes. [PDF]
PLoS ONE, 2018 Naturally occurring entomopathogenic fungi such as Conidiobolus coronatus are important regulatory factors of insect populations. GC-MS analysis of fungal cell-free filtrates showed that C.
Anna Katarzyna Wrońska +3 more
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Cell & Bioscience, 2019 Background Although the β-carboline alkaloids harman and norharman are considered as plant metabolites, they can also be secreted by fungi such as the entomopathogen Conidiobolus coronatus. Norharman and harman are also known to be reversible competitive
Anna Katarzyna Wrońska +1 more
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Investigating of harmane, harmine, and norharman as inhibitors of MDR1 and MRP1 to overcome chemotherapy resistance in cancer cells [PDF]
Scientific ReportsMultidrug resistance efflux pumps are among the primary contributors to chemotherapy failure. Therefore, the identification of novel inhibitors with greater specificity and efficacy remains a critical objective.
Neda Abdi +5 more
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Acta Crystallographica Section C Crystal Structure Communications, 2011 The structure of β-carboline, also called norharman (systematic name: 9H-pyrido[3,4-b]indole), C(11)H(8)N(2), has been determined at 110 K. Norharman is prevalent in the environment and the human body and is of wide biological interest. The structure exhibits intermolecular N-H···N hydrogen bonding, which results in a one-dimensional herringbone motif.
Robert J, Thatcher +1 more
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Acylated anthocyanin inhibited the formation of heterocyclic amines in hybrid chemical model system and its underlying mechanism [PDF]
Food Chemistry: X, 2023 Enzymatic acylation was employed to synthesize acylated anthocyanin, and a hybrid chemical model system was used for the formation of heterocyclic amines.
Hui Teng +7 more
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Occurence and partition of the β-carboline norharman in rat organs [PDF]
Life Sciences, 1993 The beta-carboline norharman was determined in plasma, brain, liver, kidney, spleen, heart and lung of the rat using HPLC with fluorescence detection. In order to improve the speed and sensitivity of this assay an earlier published sample clean-up extraction procedure and HPLC method were adjusted. Norharman was found to be present in plasma as well as
D, Fekkes, W T, Bode
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Comparison of microwave and hot-air roasting on microstructure of sesame seed, aroma-active, hazardous components, and sensory perception of sesame oil [PDF]
Food Chemistry: X, 2023 The unclear effects of microwaves, as a greener alternative to hot air, on sensory perception, aroma, and hazardous components of sesame oil were investigated.
Wen-ting Yin +6 more
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