Results 11 to 20 of about 6,872 (221)

Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor [PDF]

open access: yesTremor and Other Hyperkinetic Movements, 2012
Background: Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature.
Adrian Handforth
doaj   +5 more sources

β-Carboline (norharman) [PDF]

open access: yesActa Crystallographica Section C Crystal Structure Communications, 2011
The structure of β-carboline, also called norharman (systematic name: 9H-pyrido[3,4-b]indole), C(11)H(8)N(2), has been determined at 110 K. Norharman is prevalent in the environment and the human body and is of wide biological interest. The structure exhibits intermolecular N-H···N hydrogen bonding, which results in a one-dimensional herringbone motif.
Robert J, Thatcher   +1 more
openaire   +2 more sources

Bioactivity of selected materials for coffee substitute. [PDF]

open access: yesPLoS ONE, 2018
Epidemiological studies have suggested that coffee consumption is negatively correlated with the incidence of Parkinson's disease. Coffee contains relatively high levels of β-carbolines, which have been ascribed neuroactive effects in humans however the ...
Renata Zawirska-Wojtasiak   +4 more
doaj   +1 more source

Monoamine Oxidase Inhibition by Plant-Derived β-Carbolines; Implications for the Psychopharmacology of Tobacco and Ayahuasca

open access: yesFrontiers in Pharmacology, 2022
The monoamine oxidases (MAOs) are flavin-containing amine oxidoreductases responsible for metabolism of many biogenic amine molecules in the brain and peripheral tissues.
Ilana Berlowitz   +3 more
doaj   +1 more source

2-(2,5-Dimethoxyphenyl)pyrrole-3-carbonitrile

open access: yesMolbank, 2023
The Cadogan reaction of 2-aryl-3-nitropyridines leads to δ-carbolines. The title compound is a side product in this reaction, generated via a ring opening of a nitrene and cyclization. A crystal structure analysis gives an enormous unit cell.
Yannic Grimm   +2 more
doaj   +1 more source

Cytotoxic Bis-3,4-dihydro-β-carbolines and Bis-β-carbolines [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2002
Ten bis-beta-carboline 1, 2 and bis-3,4-dihydro-beta-carboline 3, 4 derivatives, linked between carbons 1 and 1' by a polymethylene spacer, were synthesized from bistryptamine amides 9, 10. Some of them display a micromolar IC50 towards L-1210 cells.
Wei-Qun, Jiang   +6 more
openaire   +2 more sources

UVA photoactivation of harmol enhances its antifungal activity against the phytopathogens Penicillium digitatum and Botrytis cinerea [PDF]

open access: yes, 2017
Phytopathogenic fungi responsible for post-harvest diseases on fruit and vegetables cause important economic losses. We have previously reported that harmol (1-methyl-9H-pyrido[3,4-b]indol-7-ol) is active against the causal agents of green and gray molds
Cabrerizo, Franco Martín   +5 more
core   +1 more source

Inhibition of alpha oscillations through serotonin-2A receptor activation underlies the visual effects of ayahuasca in humans [PDF]

open access: yes, 2016
Ayahuasca is an Amazonian psychotropic plant tea typically obtained from two plants, Banisteriopsis caapi and Psychotria viridis. It contains the psychedelic 5-HT2A and sigma-1 agonist N,N-dimethyltryptamine (DMT) plus ß-carboline alkaloids with ...
Alonso, Joan Francesc   +12 more
core   +3 more sources

Alkaloids from marine ascidians [PDF]

open access: yes, 2011
About 300 alkaloid structures isolated from marine ascidians are discussed in term of their occurrence, structural type and reported pharmacol. activity.
FATTORUSSO, ERNESTO   +2 more
core   +3 more sources

Probing solute distribution and acid-base behaviour in water-in-oil microemulsions by fluorescence techniques [PDF]

open access: yes, 1993
The distribution and acid-base behaviour of the four solutes harmine, chromotropic acid (4,5-dihydroxynaphthalene-2,7-disulfonate, disodium salt), 2-naphthol and 5,10,15,20-tetrakis [4-trimethylammonium)phenyl]-21H,23H-porphine tetra-p-tosylate (TTMP ...
Miguel, Maria da Graça   +3 more
core   +5 more sources

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