Results 31 to 40 of about 13,653 (252)
Tricyclic Imidazolidin-4-ones by Witkop Oxidation of Tetrahydro-β-carbolines
, 2020 1-Substituted and 1,1-disubstituted tetrahydro-β-carbolines undergo sodium periodate oxidative ring expansion in the presence of formaldehyde and other aldehydes to form 5,6-dihydro-7H-1,4-methanobenzo[e][1,4]diazonine-2,7(3H)-diones in 30–81% yield.
Douglas E. Stack (2429443) +6 more
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Bioactivity of selected materials for coffee substitute. [PDF]
PLoS ONE, 2018 Epidemiological studies have suggested that coffee consumption is negatively correlated with the incidence of Parkinson's disease. Coffee contains relatively high levels of β-carbolines, which have been ascribed neuroactive effects in humans however the ...
Renata Zawirska-Wojtasiak +4 more
doaj +1 more source
2-(2,5-Dimethoxyphenyl)pyrrole-3-carbonitrile
Molbank, 2023 The Cadogan reaction of 2-aryl-3-nitropyridines leads to δ-carbolines. The title compound is a side product in this reaction, generated via a ring opening of a nitrene and cyclization. A crystal structure analysis gives an enormous unit cell.
Yannic Grimm +2 more
doaj +1 more source
Acta Crystallographica Section C Crystal Structure Communications, 2011 The structure of β-carboline, also called norharman (systematic name: 9H-pyrido[3,4-b]indole), C(11)H(8)N(2), has been determined at 110 K. Norharman is prevalent in the environment and the human body and is of wide biological interest. The structure exhibits intermolecular N-H···N hydrogen bonding, which results in a one-dimensional herringbone motif.
Robert J, Thatcher +1 more
openaire +2 more sources
, 2023 Enantioconvergent iso-Pictet-Spengler reactions of chiral racemic ß-formyl esters and a ß-keto ester are reported, providing complex tetrahydro-γ-carbolines containing two contiguous stereocenters.
Jeffrey S. Johnson (1312380) +5 more
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, 2022 Chapter One opens with an overview of the role of pyridines in the pharmaceutical industry. This is followed by an in-depth survey of literature methods that have been reported for pyridine synthesis, including the Bohlmann-Rahtz reaction.
Tyler Nichols (4466107)
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Mild and efficient ammonium chloride catalyzed Greener synthesis of tetrahydro-β-carboline
Current Research in Green and Sustainable Chemistry, 2022 This protocol involves the NH4Cl catalyzed Pictet−Spengler reactions of tryptamine and arylaldehydes in anhydrous MeOH solvent to gives corresponding tetrahydro-β-carbolines (THβC) with 90% yield. This methodology offers mild, efficient and green reagent
Milind V. Gaikwad +2 more
doaj +1 more source
Frontiers in Nutrition, 2022 This study investigated the effect of multiple precursor amino acids on the simultaneous formation of acrylamide, β-carbolines (i. e., harmane and norharmane), and advanced glycation end products (AGEs) [i.e., Nε-(carboxymethyl)lysine and Nε ...
Cuyu Chen +8 more
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Journal of Spectroscopy, 1997 The reactions of carboline under various oxidative conditions are reported. The soft aerobic radiolysis, hydroxylation and rearrangement transformations are studied using isotopic labelling and GC–MS techniques.
Christophe Dardonville +3 more
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Electrochemical Oxidative Rearrangement of Tetrahydro-β-carbolines in Zero-gap Flow Cell [PDF]
, 2022 Oxidative rearrangement of tetrahydro-β-carbolines (THβCs) is one of the most widely used reactions for the synthesis of biologically active spirooxindoles (natural products and drug molecules).
Yiting, Zheng +8 more
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