Results 31 to 40 of about 9,923 (187)

Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension.

, 2011
Background: Tadalafil 40 mg orally once daily, was shown to be well-tolerated and efficacious for pulmonary arterial hypertension in a 16-week, double-blind, placebo (PBO)-controlled trial.
Simonneau G, Oudiz RJ, Brundage BH, Response to Tadalafil Study Group, Beardsworth A, Ghofrani HA, Barst RJ, Sundin DP, Pulmonary Arterial Hypertension, GALIE', NAZZARENO   +9 more
core   +2 more sources

An open-label, multicenter, randomized, crossover study comparing sildenafil citrate and tadalafil for treating erectile dysfunction in Chinese men naïve to phosphodiesterase 5 inhibitor therapy

Asian Journal of Andrology, 2015
The study was to compare treatment preference, efficacy, and tolerability of sildenafil citrate (sildenafil) and tadalafil for treating erectile dysfunction (ED) in Chinese men naοve to phosphodiesterase 5 (PDE5) inhibitor therapies.
Wen-Jun Bai, Hong-Jun Li, Yu-Tian Dai, Xue-You He, Yi-Ran Huang, Ji-Hong Liu, Sebastian Sorsaburu, Chen Ji, Jian-Jun Jin, Xiao-Feng Wang   +9 more
doaj   +1 more source

THE EFFECT OF COMBINED α1-ADRENERGIC BLOCKERS AND PDE-5 INHIBITORS THERAPY ON IPSS, IIEF-5, QMAX AND PVR PATIENTS BPH WITH LUTS AND ERECTILE DYSFUNCTION

Jurnal Urologi Indonesia, 2017
Purpose: Assess the efficacy of combined α1-adrenergic blocker (tamsulosin 0,4 mg) and PDE5 inhibitor (tadalafil 5 mg) therapy compared to tadalafil or tamsulosin alone in treating patient BPH with LUTS and ED.
Muhammad Ridha, Sunaryo Hardjowijoto, Johan Renaldo   +2 more
doaj   +1 more source

Effects of phosphodiesterase V inhibition alone and in combination with BNP on cardiovascular and renal response to volume load in human preclinical diastolic dysfunction

Physiological Reports, 2021
Preclinical diastolic dysfunction (PDD) results in impaired cardiorenal response to volume load (VL) which may contribute to the progression to clinical heart failure with preserved ejection fraction (HFpEF).
Siu‐Hin Wan, Paul M. McKie, Joshua P. Slusser, John C. Burnett Jr, David O. Hodge, Horng H. Chen   +5 more
doaj   +1 more source

Does the Daily Dose of Tadalafil for the Treatment of Erectile Dysfunction Increase Penile Sensation?

, 2023
Objective:To investigate the effect of tadalafil, used for treating erectile dysfunction (ED) at a daily dose of 5 mg for 12 weeks, on penile sensation.Materials and Methods:Our study included 30 male patients who applied to our andrology outpatient ...
Murat Savaş, Selim Taş, Ali Eren, Ekrem İslamoğlu   +3 more
core   +1 more source

Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Tadalafil in Colorectal Cancer

Frontiers in Pharmacology, 2022
The potential role of tadalafil, a PDE5 inhibitor, in anticancer activity and prolonged survival has been proposed. However, the systematic effects of tadalafil in colorectal cancer were not fully understood.
Pan Zhao, Yao Shen, Mengyang Li, Hanjun Dan, Zhiming Zhao, Jian Zhang   +5 more
doaj   +1 more source

Tadalafil [PDF]

pharma-kritik, 2005
Ein lang wirkender Phosphodiesterasehemmer zur Behandlung der erektilen Dysfunktion.
openaire   +2 more sources

Tadalafil Promotes the Recovery of Peripheral Neuropathy in Type II Diabetic Mice. [PDF]

PLoS ONE, 2016
We previously demonstrated that treatment of diabetic peripheral neuropathy with the short (4 hours) half-life phosphodiesterase 5 (PDE5) inhibitor, sildenafil, improved functional outcome in diabetic db/db mice.
Lei Wang, Michael Chopp, Alexandra Szalad, XueRong Lu, LongFei Jia, Mei Lu, Rui Lan Zhang, Zheng Gang Zhang   +7 more
doaj   +1 more source

Meta-Analysis of the Long-Term Efficacy and Tolerance of Tadalafil Daily Compared With Tadalafil On-Demand in Treating Men With Erectile Dysfunction

Sexual Medicine, 2019
Background: Erectile dysfunction (ED) is highly prevalent in aging men. Tadalafil daily and on-demand are widely used for the treatment of ED. Aim: We performed a meta-analysis to evaluate the efficacy and safety of tadalafil daily compared with ...
Zhongbao Zhou, MM, Hongyan Chen, MM, Jitao Wu, MD, Jipeng Wang, MM, Xuebao Zhang, MM, Jiajia Ma, MM, Yuanshan Cui, MD   +6 more
doaj   +1 more source

Endothelial Dysfunction in Patients With Erectile Dysfunction: A Double-Blind, Randomized-Control Trial Using Tadalafil

Sexual Medicine, 2019
Objective: To assess whether tadalafil improves endothelial dysfunction(EnD) in a placebo-controlled randomized-control trial. Methods: Erectile dysfunction and EnD were assessed by the International Index of Erectile Function (IIEF-5) and flow-mediated ...
Smita Pattanaik, DM, Pawan Kaundal, MS, Ravimohan S. Mavuduru, MCh, Shrawan K. Singh, MCh, Arup K. Mandal, MCh   +4 more
doaj   +1 more source