Results 31 to 40 of about 10,553 (193)

Kiwifruit Extract Attenuates Tadalafil Induced Retinal Injury in Adult Male Albino Rats: A Histological and Immunohistochemical Study [PDF]

The Egyptian Journal of Histology, 2020
Background: Tadalafil is a one of the commonly prescribed drugs for treatment of erectile dysfunction. Several ocular side effects have been reported with tadalafil therapy.
Amira Kassab, Walaa Elwan
doaj   +1 more source

Tadalafil-loaded PLGA microspheres for pulmonary administration: preparation and evaluation

, 2019
Tadalafil, a long-acting PED-5 inhibitor, is commonly used for the treatment of pulmonary arterial hypertension (PAH). However, its efficacy and clinical application are severely limited by the poor water solubility, low bioavailability and a series ...
Liu Tian (12848781), Xiuping Zhang (334570), Guihua Huang (11757071), Longmei Wang (4333165), Zhenlei Yang (12848778)   +4 more
core   +1 more source

Single and combined toxicity of tadalafil (Cilais) and microplastic in Tilapia fish (Oreochromis niloticus)

Scientific Reports
The joint impact of tadalafil (Cilais) as a pharmaceutical residue and microplastics on fish is not well comprehended. The current study examined haematological, biochemical, and antioxidant parameters, along with immunohistochemical and histological ...
Mahmoud S. Sabra, Alaa El-Din H. Sayed, Shaimaa K. A. Idriss, Hamdy A. M. Soliman   +3 more
doaj   +1 more source

Health-Care Resource Utilization and Treatment Patterns in Men with Erectile Dysfunction and Benign Prostatic Hyperplasia-Associated Lower Urinary Tract Symptoms in the United States: A Retrospective Database Study

Patient Preference and Adherence, 2023
Irwin Goldstein,1 Tarek Hassan,2 Kelly Zou,3 Victoria Divino,4 Mitch DeKoven,4 Joseph Imperato,3 Vamshi Ruthwik Anupindi,4 Jim Li3 1Department of Sexual Medicine, Alvarado Hospital, San Diego, CA, USA; 2Department of Urology, Viatris Inc, Canonsburg, PA,
Goldstein I, Hassan T, Zou K, Divino V, DeKoven M, Imperato J, Anupindi VR, Li J   +7 more
doaj  

Simultaneous spectrophotometric determination of finasteride and tadalafil in recently FDA approved Entadfi™ capsules

BMC Chemistry, 2022
Entadfi™ is a recently FDA approved pharmaceutical combination capsule of finasteride and tadalafil. It was prescribed for the treatment of urinary tract disorders caused by benign prostatic hyperplasia in men.
Ahmed H. Abdelazim, Sherif Ramzy
doaj   +1 more source

Development of a skeleton-specific antibody and Au nanoparticle-based immunochromatographic sensor for simultaneous detection of various tadalafil adulterants in health food

Food and Agricultural Immunology, 2019
In this work, a rapid, convenient and sensitive Au nanoparticle-based immunochromatographic sensor (AuNPs-ICS) for simultaneous detection of various tadalafil adulterants in health food was established for the first time, based on one high affinity and ...
Fan He, Tingting Zou, Jinyi Yang, Hong Wang, Lihua Deng, Yuanxin Tian, Zhenlin Xu, Yuanming Sun, Hongtao Lei, Xuecai Tan, Yudong Shen   +10 more
doaj   +1 more source

First Occurrence of Fatal Intoxication Involving Methiodone (IC‐26) in Finland; a Medicolegal Autopsy Case Report

Drug Testing and Analysis, EarlyView.
ABSTRACT Methiodone (IC‐26) is a non‐fentanyl novel synthetic opioid which has recently been detected in drug seizures in Europe. There is still limited data about the drug in published toxicological case work, both in non‐fatal and fatal cases. We present a medicolegal autopsy case report on a fatal intoxication in an individual undergoing opioid ...
Lasse Pakanen, Raimo A. Ketola, Pirkko Kriikku   +2 more
wiley   +1 more source

Efficacy of Continuous Dosing of Tadalafil Once Daily vs Tadalafil On Demand in Clinical Subgroups of Men With Erectile Dysfunction: A Descriptive Comparison Using the Integrated Tadalafil Databases [PDF]

, 2016
IntroductionVarious factors play a role in the development of erectile dysfunction (ED).AimTo provide a descriptive comparison of erectile function response for tadalafil on-demand (PRN) and once-daily (OAD) dosing regimens in patients with common ...
Allen Seftel, Jane Barry, Ni, Xiao, Seftel, Allen, Xiao Ni, Mulhall, John, Oelke, Matthias, Barry, Jane, Gerald Brock, Matthias Oelke, Matt Rosenberg, D'Souza, Deborah, Rosenberg, Matt, Brock, Gerald, John Mulhall, Deborah D'Souza   +15 more
core   +1 more source

Synthesis of β‐ and γ‐Carbolinones Through a Fe(III)‐Mediated Radical 6‐Endo‐Trig Cyclization of Indole‐Based Ugi 4‐CR Adducts

European Journal of Organic Chemistry, EarlyView.
A practical strategy for synthesizing β‐ and γ‐carbolinones from indole‐based Ugi 4‐CR adducts through an intramolecular radical cyclization using Fe(III)–H species is presented. This approach enables the efficient synthesis of spiro‐carbolinones under mild reaction conditions and demonstrates the effectiveness of secondary radicals in both cyclization
María F. Olvera‐Granados, Luis A. Polindara‐García   +1 more
wiley   +1 more source

Protective effect of tadalafil in diabetic nephropathy induced rat model [PDF]

, 2017
Background: Among various mechanisms involved in the pathogenesis of diabetic nephropathy (DN), abnormalities in renal nitric oxide (NO) generation has attracted a lot of attention.
Omaima M. Abd Allah, Abdel Hamid M. Elhawary, Abd Allah, Omaima M., Elhawary, Abdel Hamid M.   +3 more
core   +1 more source